Eur Respir J:机械通气的社区获得性肺炎患者急性呼吸窘迫综合征!

2018-04-04 xing.T MedSci原创

由此可见,ARDS作为CAP的并发症发生于29%的机械通气患者中,但与病因或死亡率无关。

近日,呼吸疾病领域权威杂志Eur Respir J上发表了一篇研究文章,研究人员的目的是使用柏林定义来评估入住重症监护病房(ICU)的社区获得性肺炎(CAP)患者急性呼吸窘迫综合征(ARDS)的发病率、特征、病因、危险因素和死亡率。

研究人员前瞻性地纳入了连续就诊的机械通气的成年入住ICU的CAP患者,并将其与没有ARDS的机械通气患者进行比较。主要结局为30天的死亡率。

在5334例住院的CAP患者中,930例(17%)患者入住ICU,432例患者需要机械通气;125例(29%)病例符合柏林ARDS标准。 2%的住院患者和13%的ICU患者存在ARDS。根据基线动脉氧分压/吸入氧分数的比值,分别有60例(48%)、49例(40%)和15例(12%)轻度、中度和重度ARDS患者。肺炎链球菌是最常见的病原体,组间病因无显著差异。多变量分析显示器官系统功能障碍和既往使用抗生素是ARDS的独立危险因素,而既往吸入糖皮质激素与较低风险独立相关。经过倾向调整的多变量分析证实,有和无ARDS患者的30天死亡率相似(25% vs. 30%,P=0.25)。

由此可见,ARDS作为CAP的并发症发生于29%的机械通气患者中,但与病因或死亡率无关。

原始出处:

Catia Cilloniz,,et al. Acute respiratory distress syndrome in mechanically ventilated patients with community-acquired pneumonia.Eur Respir J. 2018. http://erj.ersjournals.com/content/51/3/1702215

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    2018-04-06 秀红

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为了更好的落实国家医改要求,发挥区域性三甲医院的辐射带动作用,1月20日,由西安医学院第一附属医院与省呼吸病预防与诊治工程研究中心承办的“紧密医联体下重症呼吸诊治建设启动会”成功召开。标志着由该院牵头组建的机械通气协作中心联盟正式成立。该联盟由17位省内呼吸领域的专家组成员,27家医院组成。北京协和医院MICU主任杜斌教授、卫生部中日医院对外交流联络处贾存波处长、东南大学附属中大医院谢剑锋博士、西