Allergy Asthma Clin Immunol:5种草花粉提取混合物舌下免疫治疗的观察性群体研究

2018-10-12 AlexYang MedSci原创

过敏性鼻炎影响着西方欧洲人口群体的四分之一之多。预防过敏源免疫疗法在减少急性症状发作(花粉过敏)中是有效的。到目前为止,一种5种草花粉提取混合物舌下免疫治疗(5GPE-SLIT)被用来治疗花粉过敏的过敏性鼻炎。最近,有研究人员描述了真实世界中5GPE-SLIT的治疗情况。研究包括了280名成年人和203名儿童。处方信息包括了82.5%的成年人和86.7%的儿童。研究人员对所有的患者进行了皮刺测试。

过敏性鼻炎影响着西方欧洲人口群体的四分之一之多。预防过敏源免疫疗法在减少急性症状发作(花粉过敏)中是有效的。到目前为止,一种5种草花粉提取混合物舌下免疫治疗(5GPE-SLIT)被用来治疗花粉过敏的过敏性鼻炎。最近,有研究人员描述了真实世界中5GPE-SLIT的治疗情况。

研究包括了280名成年人和203名儿童。处方信息包括了82.5%的成年人和86.7%的儿童。研究人员对所有的患者进行了皮刺测试。研究人员在花粉季节开始之前的3-5个月,对85.3%的患者开始进行了5GPE-SLIT。在11%的患者中,治疗在花粉季节开始时中,主要是因为副作用的出现。研究发现,在成年人和儿童中的平均治疗时间分别为5.2个月和5.6个月。在跟踪调查末期,花粉季节中症状的出现在75%的成年人和85.7%的儿童中是间断的,并且程度分别在61.8%的成年人和66.0%的儿童中是较轻的。在5GPE-SLIT期间,多于50%的患者没有出现之前1年的症状,这些症状包括鼻塞、鼻溢、重复性打喷嚏、鼻窦炎和鼻瘙痒。

最后,研究人员指出,5GPE-SLIT的使用与处方的信息是一致的,并且与AR严重度的改善相关,并且消除了大约一半患者的主要AR症状。

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    2019-07-21 skhzy
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    2018-12-15 xjy13
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    2018-10-14 膀胱癌
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