神经科

订阅

MedSci主页 / 所有栏目 / 神经科

Elife：消除睡眠障碍？可能需要求助肌肉而非大脑

2017-08-06 张翼轸 生物探索

睡眠障碍肌肉大脑
关注

过去关于睡眠问题的对策研究一直集中在大脑方面，不过近期一项研究的结果要改变人们对大脑“掌控一切睡眠问题”的印象了

过去关于睡眠问题的对策研究一直集中在大脑方面，不过近期一项研究的结果要改变人们对大脑“掌控一切睡眠问题”的印象了。

这项由德州大学西南医学中心Peter O’Donnell Jr.脑研究所与其他两家医疗中心共同参与的研究指出，要解决过度嗜睡等问题，肌肉组织蛋白质可能是除大脑之外的另一个突破口。

这篇发布在eLife上的文章称，研究者在小鼠身上发现了一种能够调节其睡眠长度和睡眠习惯的物质——BMAL1生物钟蛋白质。实验结果显示，肌肉内高BMAL1蛋白质含量能够帮助小鼠较快地从睡眠剥夺中恢复；相反地，肌肉内缺乏BMAL1蛋白质时，小鼠会表现出嗜睡、睡眠剥夺后难以恢复等状况。与之在小鼠肌肉中明显的作用效果相比较，BMAL1蛋白质在小鼠大脑中几乎没有产生影响。

此项发现，让兼任西南医学中心神经科学主席及霍华德·休斯医学研究所研究员的Dr. Joseph Takahashi很兴奋：“肌肉组织中的某些因素能向大脑传递影响睡眠的信号，这一发现完全出乎意料，改变了我们对睡眠控制方式的认识。如果人体存在类似的传递途径，那么将会有新的药物靶点来治疗睡眠障碍。”

研究人员表示，新发现最终可能带来新疗法。对于飞行员、军人等需要在工作中长时间保持清醒的人来说，这或许是解决他们睡眠问题的利好消息。

原始出处：
Ehlen JC, Brager AJ, Baggs J,et al.Bmal1 function in skeletal muscle regulates sleep.Elife. 2017 Jul 20;6. pii: e26557. doi: 10.7554/eLife.26557. [Epub ahead of print]

版权声明：
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料，版权均属于梅斯医学所有。非经授权，任何媒体、网站或个人不得转载，授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章，或“梅斯号”自媒体发布的文章，仅系出于传递更多信息之目的，本站仅负责审核内容合规，其内容不代表本站立场，本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系，我们将立即进行删除处理。
在此留言
评论区 (27)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=2068512, encodeId=7b6220685126d, content=<a href='/topic/show?id=59371088215' target=_blank style='color:#2F92EE;'>#Life#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10882, encryptionId=59371088215, topicName=Life)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fc8528, createdName=clmlylxy, createdTime=Wed Feb 14 02:11:00 CST 2018, time=2018-02-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1973011, encodeId=b94319e301128, content=<a href='/topic/show?id=72d566e3a6' target=_blank style='color:#2F92EE;'>#eLife#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6673, encryptionId=72d566e3a6, topicName=eLife)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/C2EFD5CFB07FE291138AD4FD0C98E3DE/100, createdBy=e3d52500031, createdName=膀胱癌, createdTime=Wed Dec 27 00:11:00 CST 2017, time=2017-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=234617, encodeId=b59723461e03, content=消除睡眠障特。, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Fri Aug 18 07:47:40 CST 2017, time=2017-08-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233980, encodeId=28f923398003, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Wed Aug 16 07:17:52 CST 2017, time=2017-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233687, encodeId=171f23368ebf, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Tue Aug 15 06:40:53 CST 2017, time=2017-08-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233313, encodeId=cf5523331304, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Mon Aug 14 00:54:06 CST 2017, time=2017-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232981, encodeId=bf15232981d1, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Sun Aug 13 00:08:17 CST 2017, time=2017-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232688, encodeId=8208232688cf, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Sat Aug 12 05:17:40 CST 2017, time=2017-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232326, encodeId=ff1b232326c6, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Fri Aug 11 06:30:26 CST 2017, time=2017-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232022, encodeId=a35d23202284, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Thu Aug 10 06:28:28 CST 2017, time=2017-08-10, status=1, ipAttribution=)]
    2018-02-14 clmlylxy

    #Life#

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=2068512, encodeId=7b6220685126d, content=<a href='/topic/show?id=59371088215' target=_blank style='color:#2F92EE;'>#Life#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10882, encryptionId=59371088215, topicName=Life)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fc8528, createdName=clmlylxy, createdTime=Wed Feb 14 02:11:00 CST 2018, time=2018-02-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1973011, encodeId=b94319e301128, content=<a href='/topic/show?id=72d566e3a6' target=_blank style='color:#2F92EE;'>#eLife#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6673, encryptionId=72d566e3a6, topicName=eLife)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/C2EFD5CFB07FE291138AD4FD0C98E3DE/100, createdBy=e3d52500031, createdName=膀胱癌, createdTime=Wed Dec 27 00:11:00 CST 2017, time=2017-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=234617, encodeId=b59723461e03, content=消除睡眠障特。, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Fri Aug 18 07:47:40 CST 2017, time=2017-08-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233980, encodeId=28f923398003, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Wed Aug 16 07:17:52 CST 2017, time=2017-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233687, encodeId=171f23368ebf, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Tue Aug 15 06:40:53 CST 2017, time=2017-08-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233313, encodeId=cf5523331304, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Mon Aug 14 00:54:06 CST 2017, time=2017-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232981, encodeId=bf15232981d1, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Sun Aug 13 00:08:17 CST 2017, time=2017-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232688, encodeId=8208232688cf, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Sat Aug 12 05:17:40 CST 2017, time=2017-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232326, encodeId=ff1b232326c6, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Fri Aug 11 06:30:26 CST 2017, time=2017-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232022, encodeId=a35d23202284, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Thu Aug 10 06:28:28 CST 2017, time=2017-08-10, status=1, ipAttribution=)]
    2017-12-27 膀胱癌

    #eLife#

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=2068512, encodeId=7b6220685126d, content=<a href='/topic/show?id=59371088215' target=_blank style='color:#2F92EE;'>#Life#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10882, encryptionId=59371088215, topicName=Life)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fc8528, createdName=clmlylxy, createdTime=Wed Feb 14 02:11:00 CST 2018, time=2018-02-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1973011, encodeId=b94319e301128, content=<a href='/topic/show?id=72d566e3a6' target=_blank style='color:#2F92EE;'>#eLife#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6673, encryptionId=72d566e3a6, topicName=eLife)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/C2EFD5CFB07FE291138AD4FD0C98E3DE/100, createdBy=e3d52500031, createdName=膀胱癌, createdTime=Wed Dec 27 00:11:00 CST 2017, time=2017-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=234617, encodeId=b59723461e03, content=消除睡眠障特。, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Fri Aug 18 07:47:40 CST 2017, time=2017-08-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233980, encodeId=28f923398003, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Wed Aug 16 07:17:52 CST 2017, time=2017-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233687, encodeId=171f23368ebf, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Tue Aug 15 06:40:53 CST 2017, time=2017-08-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233313, encodeId=cf5523331304, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Mon Aug 14 00:54:06 CST 2017, time=2017-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232981, encodeId=bf15232981d1, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Sun Aug 13 00:08:17 CST 2017, time=2017-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232688, encodeId=8208232688cf, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Sat Aug 12 05:17:40 CST 2017, time=2017-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232326, encodeId=ff1b232326c6, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Fri Aug 11 06:30:26 CST 2017, time=2017-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232022, encodeId=a35d23202284, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Thu Aug 10 06:28:28 CST 2017, time=2017-08-10, status=1, ipAttribution=)]
    2017-08-18 jyzxjiangqin

    消除睡眠障特。

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=2068512, encodeId=7b6220685126d, content=<a href='/topic/show?id=59371088215' target=_blank style='color:#2F92EE;'>#Life#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10882, encryptionId=59371088215, topicName=Life)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fc8528, createdName=clmlylxy, createdTime=Wed Feb 14 02:11:00 CST 2018, time=2018-02-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1973011, encodeId=b94319e301128, content=<a href='/topic/show?id=72d566e3a6' target=_blank style='color:#2F92EE;'>#eLife#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6673, encryptionId=72d566e3a6, topicName=eLife)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/C2EFD5CFB07FE291138AD4FD0C98E3DE/100, createdBy=e3d52500031, createdName=膀胱癌, createdTime=Wed Dec 27 00:11:00 CST 2017, time=2017-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=234617, encodeId=b59723461e03, content=消除睡眠障特。, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Fri Aug 18 07:47:40 CST 2017, time=2017-08-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233980, encodeId=28f923398003, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Wed Aug 16 07:17:52 CST 2017, time=2017-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233687, encodeId=171f23368ebf, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Tue Aug 15 06:40:53 CST 2017, time=2017-08-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233313, encodeId=cf5523331304, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Mon Aug 14 00:54:06 CST 2017, time=2017-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232981, encodeId=bf15232981d1, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Sun Aug 13 00:08:17 CST 2017, time=2017-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232688, encodeId=8208232688cf, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Sat Aug 12 05:17:40 CST 2017, time=2017-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232326, encodeId=ff1b232326c6, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Fri Aug 11 06:30:26 CST 2017, time=2017-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232022, encodeId=a35d23202284, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Thu Aug 10 06:28:28 CST 2017, time=2017-08-10, status=1, ipAttribution=)]
    2017-08-16 ffffffffff

    谢谢分享谢谢分享

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=2068512, encodeId=7b6220685126d, content=<a href='/topic/show?id=59371088215' target=_blank style='color:#2F92EE;'>#Life#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10882, encryptionId=59371088215, topicName=Life)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fc8528, createdName=clmlylxy, createdTime=Wed Feb 14 02:11:00 CST 2018, time=2018-02-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1973011, encodeId=b94319e301128, content=<a href='/topic/show?id=72d566e3a6' target=_blank style='color:#2F92EE;'>#eLife#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6673, encryptionId=72d566e3a6, topicName=eLife)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/C2EFD5CFB07FE291138AD4FD0C98E3DE/100, createdBy=e3d52500031, createdName=膀胱癌, createdTime=Wed Dec 27 00:11:00 CST 2017, time=2017-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=234617, encodeId=b59723461e03, content=消除睡眠障特。, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Fri Aug 18 07:47:40 CST 2017, time=2017-08-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233980, encodeId=28f923398003, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Wed Aug 16 07:17:52 CST 2017, time=2017-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233687, encodeId=171f23368ebf, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Tue Aug 15 06:40:53 CST 2017, time=2017-08-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233313, encodeId=cf5523331304, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Mon Aug 14 00:54:06 CST 2017, time=2017-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232981, encodeId=bf15232981d1, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Sun Aug 13 00:08:17 CST 2017, time=2017-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232688, encodeId=8208232688cf, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Sat Aug 12 05:17:40 CST 2017, time=2017-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232326, encodeId=ff1b232326c6, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Fri Aug 11 06:30:26 CST 2017, time=2017-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232022, encodeId=a35d23202284, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Thu Aug 10 06:28:28 CST 2017, time=2017-08-10, status=1, ipAttribution=)]
    2017-08-15 ffffffffff

    谢谢分享谢谢分享

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=2068512, encodeId=7b6220685126d, content=<a href='/topic/show?id=59371088215' target=_blank style='color:#2F92EE;'>#Life#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10882, encryptionId=59371088215, topicName=Life)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fc8528, createdName=clmlylxy, createdTime=Wed Feb 14 02:11:00 CST 2018, time=2018-02-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1973011, encodeId=b94319e301128, content=<a href='/topic/show?id=72d566e3a6' target=_blank style='color:#2F92EE;'>#eLife#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6673, encryptionId=72d566e3a6, topicName=eLife)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/C2EFD5CFB07FE291138AD4FD0C98E3DE/100, createdBy=e3d52500031, createdName=膀胱癌, createdTime=Wed Dec 27 00:11:00 CST 2017, time=2017-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=234617, encodeId=b59723461e03, content=消除睡眠障特。, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Fri Aug 18 07:47:40 CST 2017, time=2017-08-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233980, encodeId=28f923398003, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Wed Aug 16 07:17:52 CST 2017, time=2017-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233687, encodeId=171f23368ebf, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Tue Aug 15 06:40:53 CST 2017, time=2017-08-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233313, encodeId=cf5523331304, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Mon Aug 14 00:54:06 CST 2017, time=2017-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232981, encodeId=bf15232981d1, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Sun Aug 13 00:08:17 CST 2017, time=2017-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232688, encodeId=8208232688cf, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Sat Aug 12 05:17:40 CST 2017, time=2017-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232326, encodeId=ff1b232326c6, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Fri Aug 11 06:30:26 CST 2017, time=2017-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232022, encodeId=a35d23202284, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Thu Aug 10 06:28:28 CST 2017, time=2017-08-10, status=1, ipAttribution=)]
    2017-08-14 ffffffffff

    谢谢分享谢谢分享

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=2068512, encodeId=7b6220685126d, content=<a href='/topic/show?id=59371088215' target=_blank style='color:#2F92EE;'>#Life#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10882, encryptionId=59371088215, topicName=Life)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fc8528, createdName=clmlylxy, createdTime=Wed Feb 14 02:11:00 CST 2018, time=2018-02-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1973011, encodeId=b94319e301128, content=<a href='/topic/show?id=72d566e3a6' target=_blank style='color:#2F92EE;'>#eLife#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6673, encryptionId=72d566e3a6, topicName=eLife)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/C2EFD5CFB07FE291138AD4FD0C98E3DE/100, createdBy=e3d52500031, createdName=膀胱癌, createdTime=Wed Dec 27 00:11:00 CST 2017, time=2017-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=234617, encodeId=b59723461e03, content=消除睡眠障特。, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Fri Aug 18 07:47:40 CST 2017, time=2017-08-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233980, encodeId=28f923398003, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Wed Aug 16 07:17:52 CST 2017, time=2017-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233687, encodeId=171f23368ebf, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Tue Aug 15 06:40:53 CST 2017, time=2017-08-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233313, encodeId=cf5523331304, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Mon Aug 14 00:54:06 CST 2017, time=2017-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232981, encodeId=bf15232981d1, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Sun Aug 13 00:08:17 CST 2017, time=2017-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232688, encodeId=8208232688cf, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Sat Aug 12 05:17:40 CST 2017, time=2017-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232326, encodeId=ff1b232326c6, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Fri Aug 11 06:30:26 CST 2017, time=2017-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232022, encodeId=a35d23202284, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Thu Aug 10 06:28:28 CST 2017, time=2017-08-10, status=1, ipAttribution=)]
    2017-08-13 ffffffffff

    谢谢分享谢谢分享

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=2068512, encodeId=7b6220685126d, content=<a href='/topic/show?id=59371088215' target=_blank style='color:#2F92EE;'>#Life#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10882, encryptionId=59371088215, topicName=Life)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fc8528, createdName=clmlylxy, createdTime=Wed Feb 14 02:11:00 CST 2018, time=2018-02-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1973011, encodeId=b94319e301128, content=<a href='/topic/show?id=72d566e3a6' target=_blank style='color:#2F92EE;'>#eLife#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6673, encryptionId=72d566e3a6, topicName=eLife)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/C2EFD5CFB07FE291138AD4FD0C98E3DE/100, createdBy=e3d52500031, createdName=膀胱癌, createdTime=Wed Dec 27 00:11:00 CST 2017, time=2017-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=234617, encodeId=b59723461e03, content=消除睡眠障特。, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Fri Aug 18 07:47:40 CST 2017, time=2017-08-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233980, encodeId=28f923398003, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Wed Aug 16 07:17:52 CST 2017, time=2017-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233687, encodeId=171f23368ebf, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Tue Aug 15 06:40:53 CST 2017, time=2017-08-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233313, encodeId=cf5523331304, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Mon Aug 14 00:54:06 CST 2017, time=2017-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232981, encodeId=bf15232981d1, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Sun Aug 13 00:08:17 CST 2017, time=2017-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232688, encodeId=8208232688cf, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Sat Aug 12 05:17:40 CST 2017, time=2017-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232326, encodeId=ff1b232326c6, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Fri Aug 11 06:30:26 CST 2017, time=2017-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232022, encodeId=a35d23202284, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Thu Aug 10 06:28:28 CST 2017, time=2017-08-10, status=1, ipAttribution=)]
    2017-08-12 ffffffffff

    谢谢分享谢谢分享

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=2068512, encodeId=7b6220685126d, content=<a href='/topic/show?id=59371088215' target=_blank style='color:#2F92EE;'>#Life#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10882, encryptionId=59371088215, topicName=Life)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fc8528, createdName=clmlylxy, createdTime=Wed Feb 14 02:11:00 CST 2018, time=2018-02-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1973011, encodeId=b94319e301128, content=<a href='/topic/show?id=72d566e3a6' target=_blank style='color:#2F92EE;'>#eLife#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6673, encryptionId=72d566e3a6, topicName=eLife)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/C2EFD5CFB07FE291138AD4FD0C98E3DE/100, createdBy=e3d52500031, createdName=膀胱癌, createdTime=Wed Dec 27 00:11:00 CST 2017, time=2017-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=234617, encodeId=b59723461e03, content=消除睡眠障特。, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Fri Aug 18 07:47:40 CST 2017, time=2017-08-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233980, encodeId=28f923398003, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Wed Aug 16 07:17:52 CST 2017, time=2017-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233687, encodeId=171f23368ebf, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Tue Aug 15 06:40:53 CST 2017, time=2017-08-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233313, encodeId=cf5523331304, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Mon Aug 14 00:54:06 CST 2017, time=2017-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232981, encodeId=bf15232981d1, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Sun Aug 13 00:08:17 CST 2017, time=2017-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232688, encodeId=8208232688cf, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Sat Aug 12 05:17:40 CST 2017, time=2017-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232326, encodeId=ff1b232326c6, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Fri Aug 11 06:30:26 CST 2017, time=2017-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232022, encodeId=a35d23202284, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Thu Aug 10 06:28:28 CST 2017, time=2017-08-10, status=1, ipAttribution=)]
    2017-08-11 ffffffffff

    谢谢分享谢谢分享

    0

  10. [GetPortalCommentsPageByObjectIdResponse(id=2068512, encodeId=7b6220685126d, content=<a href='/topic/show?id=59371088215' target=_blank style='color:#2F92EE;'>#Life#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10882, encryptionId=59371088215, topicName=Life)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fc8528, createdName=clmlylxy, createdTime=Wed Feb 14 02:11:00 CST 2018, time=2018-02-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1973011, encodeId=b94319e301128, content=<a href='/topic/show?id=72d566e3a6' target=_blank style='color:#2F92EE;'>#eLife#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6673, encryptionId=72d566e3a6, topicName=eLife)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/C2EFD5CFB07FE291138AD4FD0C98E3DE/100, createdBy=e3d52500031, createdName=膀胱癌, createdTime=Wed Dec 27 00:11:00 CST 2017, time=2017-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=234617, encodeId=b59723461e03, content=消除睡眠障特。, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Fri Aug 18 07:47:40 CST 2017, time=2017-08-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233980, encodeId=28f923398003, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Wed Aug 16 07:17:52 CST 2017, time=2017-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233687, encodeId=171f23368ebf, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Tue Aug 15 06:40:53 CST 2017, time=2017-08-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233313, encodeId=cf5523331304, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Mon Aug 14 00:54:06 CST 2017, time=2017-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232981, encodeId=bf15232981d1, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Sun Aug 13 00:08:17 CST 2017, time=2017-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232688, encodeId=8208232688cf, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Sat Aug 12 05:17:40 CST 2017, time=2017-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232326, encodeId=ff1b232326c6, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Fri Aug 11 06:30:26 CST 2017, time=2017-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232022, encodeId=a35d23202284, content=谢谢分享谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160823/IMG57BBA4F88B06B5498.jpg, createdBy=29f71719637, createdName=ffffffffff, createdTime=Thu Aug 10 06:28:28 CST 2017, time=2017-08-10, status=1, ipAttribution=)]
    2017-08-10 ffffffffff

    谢谢分享谢谢分享

    0

以上为热门评论，梅斯医学App还有更多内容

相关资讯

盘点：近期睡眠障碍相关研究进展

睡眠量不正常以及睡眠中出现异常行为的表现﹐也是睡眠和觉醒正常节律性交替紊乱的表现。可由多种因素引起，常与躯体疾病有关，包括睡眠失调和异态睡眠。睡眠与人的健康息息相关。【1】J Pediatr：过敏性疾病或睡眠障碍患儿更容易久坐不动根据研究结果，包括哮喘、湿疹和枯草热在内的严重的特应性疾病，联合睡眠障碍与儿童更高风险的久坐行为有关。西北大学费因伯格医学院的Mark A. Strom和Jonath

半梦半醒之时，大脑可能经历什么？

睡眠麻痹，中国俗称“鬼压床”，是一种颇带神秘色彩的生理现象。通常发生在半睡半醒之时。据统计，50%的一生中都至少发生过一次睡眠麻痹。睡眠麻痹病理机制不明确。压力，焦虑，紧张，疲惫，失眠都可能诱发睡眠麻痹……

Sleep Med： 听力损失可以调节睡眠障碍呼吸中的执行功能损伤

由于共有的扁桃体肥大病因，睡眠障碍呼吸（SDB）与传导性听力损失在早期儿童时期往往是共同的病因。听力损失与执行功能的损伤和行为障碍独立相关。最近，有研究人员假设了患有SDB的儿童也许可以通过听力损失调节。研究包括了58名儿童，其中37名打鼾并等待增殖腺扁桃体切除术，还有21名非打鼾的对照，年龄在3到5岁。研究人员对他们进行了纯音听觉、长处和困难（SDQ）、执行功能行为速度（BRIEF-P）和儿童中

J Rheumatol：银屑病的睡眠障碍：流行病学及相关因素

银屑病患者睡眠质量差。睡眠差与疲劳、焦虑和EQ-5D降低相关。PsA患者中睡眠差与活动性关节炎有关。

Neurology：睡眠障碍与认知正常成人淀粉样变性的脑脊液生物标志物有关！

由此可见，自我报告的睡眠不佳与认知正常的AD风险患者更大的AD相关的病理学异常相关。改善睡眠的有效策略是可行的；因此，睡眠健康可能是早期干预以减轻AD发病的一个容易实现的目标。

J Gastroen Hepatol：睡眠障碍与胃食道反流之间的关系

胃食道反流病与焦虑以及现阶段抑郁显著相关，其相关性部分是由于睡眠障碍引起的。对于胃食道反流病患者应同时进行心理健康评估以识别潜在的混杂因素，实现对症状的有效控制