Hypertension:限钠和DASH饮食中血压变化的时间过程

2017-11-03 吴星 环球医学

2017年11月,发表在《Hypertension》的一项由美国科学家进行的研究,考察了限钠和DASH饮食中血压变化的时间过程。

2017年11月,发表在《Hypertension》的一项由美国科学家进行的研究,考察了限钠和DASH饮食中血压变化的时间过程。

限钠和饮食法降压(Dietary Approaches to Stop Hypertension,DASH)膳食均可以降低血压(BP);然而,它们对BP随时间变化的影响模式未知。

在DASH-钠试验中,高血压前期/1期、未使用降压药物的成人被随机分配至典型美国饮食组(对照组)或DASH组。在他们被分配的饮食中,参与者在4周的时间内随机吃3种不同水平的钠(50、100和150 mmol/d,2100 kcal)。每周测量BP,为期12周;纳入412例受试者(57%为女性;57%为黑人;平均年龄,48岁;平均收缩压[SBP]/舒张压[DBP],135/86 mm Hg)。

对于对照组而言,高钠膳食1至4周的SBP/DBP无改变(周变化,-0.04/0.06 mm Hg/周)vs低钠膳食的BP有进行性降低(-0.94/-0.70 mm Hg/周;SBP和DBP时间与钠相互作用P<0.001)。对于DASH组而言,高钠膳食组SBP/DBP变化为-0.60/-0.16 mm Hg/周vs低钠膳食组为-0.42/-0.54 mm Hg/周(SBP时间与钠相互作用P=0.56,DBP时间与钠相互作用P=0.10)。DASH组与对照组相比,1周后DASH改变SBP/DBP -4.36/-1.07 mm Hg,此时观察到的效果占比最大,而SBP(相互作用P=0.97)或DBP(相互作用P=0.70)的每周改变率无显着差异。

在典型美国饮食环境下,低钠饮食降低血压而无停滞期,表明4周时未完全达到低钠的全部效果。相反,与对照组相比,DASH在1周内降低BP,之后无进一步效果

原始出处:

Juraschek SP, Woodward M, Sacks FM,et al. Time Course of Change in Blood Pressure From Sodium Reduction and the DASH Diet. Hypertension. 2017 Nov;70(5):923-929. doi: 10.1161/HYPERTENSIONAHA.117.10017.

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    2018-04-24 tm10051981
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    2018-03-28 feather89
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    2017-11-05 kksonne
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    2017-11-04 清风拂面

    谢谢分享.学习了

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=1784095, encodeId=ddb01e8409571, content=<a href='/topic/show?id=82d25e154b' target=_blank style='color:#2F92EE;'>#DASH#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5715, encryptionId=82d25e154b, topicName=DASH)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=76fa353, createdName=tm10051981, createdTime=Tue Apr 24 23:47:00 CST 2018, time=2018-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2038776, encodeId=c7f42038e76dd, content=<a href='/topic/show?id=b45d1e274e8' target=_blank style='color:#2F92EE;'>#TENS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17274, encryptionId=b45d1e274e8, topicName=TENS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3b172500206, createdName=12498ebem19暂无昵称, createdTime=Mon Sep 24 18:47:00 CST 2018, time=2018-09-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1709688, encodeId=d1171e096888e, content=<a href='/topic/show?id=4cc58893ea0' target=_blank style='color:#2F92EE;'>#血压变化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=88937, encryptionId=4cc58893ea0, topicName=血压变化)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f1b531772449, createdName=ms1467340776200723, createdTime=Fri Mar 09 18:47:00 CST 2018, time=2018-03-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1726846, encodeId=cf441e26846a6, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Wed Mar 28 15:47:00 CST 2018, time=2018-03-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2042086, encodeId=1ff720420862f, content=<a href='/topic/show?id=74685e1614' target=_blank style='color:#2F92EE;'>#DASH饮食#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5716, encryptionId=74685e1614, topicName=DASH饮食)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d275294, createdName=andy2087, createdTime=Tue Aug 28 15:47:00 CST 2018, time=2018-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1301190, encodeId=d3e51301190df, content=<a href='/topic/show?id=38e32852fe' target=_blank style='color:#2F92EE;'>#ASH#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2852, encryptionId=38e32852fe, topicName=ASH)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=39a0295, createdName=kksonne, createdTime=Sun Nov 05 05:47:00 CST 2017, time=2017-11-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1501221, encodeId=e8aa1501221eb, content=<a href='/topic/show?id=f2db9238f9' target=_blank style='color:#2F92EE;'>#Hypertension#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9238, encryptionId=f2db9238f9, topicName=Hypertension)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=11ff9497046, createdName=jambiya, createdTime=Sun Nov 05 05:47:00 CST 2017, time=2017-11-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=258591, encodeId=646d2585919e, content=谢谢分享.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Sat Nov 04 11:54:25 CST 2017, time=2017-11-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=258364, encodeId=ba6225836419, content=学习了.获益匪浅!感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/07/17/0ed05bbc4eb124766d2a39104932ec4e.jpg, createdBy=5afd2091871, createdName=情途末路, createdTime=Fri Nov 03 14:53:05 CST 2017, time=2017-11-03, status=1, ipAttribution=)]
    2017-11-03 情途末路

    学习了.获益匪浅!感谢分享

    0

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