JACC:乳头状弹力纤维瘤的手术切除和超声心动图检测

2015-06-03 崔倩 译 MedSci原创

背景:乳头状弹力纤维瘤(PFE)是良性的肿瘤,而且很少有可用的结果数据。    意义:本研究旨在描述手术切除PFE和超声心动图检测PFE(但不手术)的频率和临床过程。    方法:研究人员对梅奥诊所病理及超声心动图数据库(1995年1月1日到2010年12月31日)进行了查询,结果显示在511例患者中:第1组(n=185),包括手术切除,

背景:乳头状弹力纤维瘤(PFE)是良性的肿瘤,而且很少有可用的结果数据。
    
意义:本研究旨在描述手术切除PFE和超声心动图检测PFE(但不手术)的频率和临床过程。
    
方法:研究人员对梅奥诊所病理及超声心动图数据库(1995年1月1日到2010年12月31日)进行了查询,结果显示在511例患者中:第1组(n=185),包括手术切除,病理证实PFE的患者;1a组(n=94;51%)在初次手术切除PFE的患者;1b组(n=91;49%)在另一次心脏手术的时切除PFE的患者。第2组(n=326)有PFE的超声心动图的表明,但无心脏手术切除PFE的患者。
    
结果:第1组平均年龄为63±14岁(116名女性[63%])。在研究期间,研究人员通过病理数据库确定了112例心脏黏液瘤患者,超声心动图数据库确定142例。第2组平均年龄为67±14岁(女性162名[50%])。PFE最常发生在心脏瓣膜(n=400[78%])。在第1组中,58例(32%)患者的症状是短暂性脑缺血发作或中风。随着手术切除瓣膜PFE,92例(98%)保存了心脏瓣膜。3例(1.6%)患者有复发记录。在1年时,随访中风风险在1,1a和1b组中分别为2%,0%和4%;在5年时,分别为8%,5%和11%。第2组在1年和5年时脑血管意外风险分别是6%和13%。
    
结论:超声心动图疑似PFE但不接受手术切除的患者,脑血管意外发生率和死亡率增加。


    
对疑似乳头状弹力纤维瘤(PFE)患者,这个决策树评论管理选项。AO =主动脉回声;超声心动图;LA = 左心房;SBE亚急性细菌性心内膜炎;SLE=系统性红斑狼疮。

原始出处:

Syahidah S. Tamin, MBBS∗; Joseph J. Maleszewski, MD∗; Christopher G. Scott, MS‡; S.K. Khan, MBBS§; William D. Edwards, MD∗; Charles J. Bruce, MD∗; Jae K. Oh, MD∗; Patricia A. Pellikka, MD∗; Kyle W. Klarich, MD∗,Prognostic and Bioepidemiologic Implications of Papillary Fibroelastomas,JACC,2015.6.2

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    2016-04-23 hbwxf
  5. [GetPortalCommentsPageByObjectIdResponse(id=2023195, encodeId=4c7d2023195bf, content=<a href='/topic/show?id=a5f45008190' target=_blank style='color:#2F92EE;'>#弹力纤维瘤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50081, encryptionId=a5f45008190, topicName=弹力纤维瘤)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=395f25, createdName=bioon1, createdTime=Wed Aug 26 07:16:00 CST 2015, time=2015-08-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2044964, encodeId=55992044964d3, content=<a href='/topic/show?id=a4d02358610' target=_blank style='color:#2F92EE;'>#乳头状#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23586, encryptionId=a4d02358610, topicName=乳头状)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ce5632, createdName=jianjun66, createdTime=Thu Oct 01 13:16:00 CST 2015, time=2015-10-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1650996, encodeId=6fc1165099636, content=<a href='/topic/show?id=2aa35090181' target=_blank style='color:#2F92EE;'>#心动图#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50901, encryptionId=2aa35090181, topicName=心动图)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8a7624121693, createdName=zhu_jun9845, createdTime=Fri Apr 08 14:16:00 CST 2016, time=2016-04-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1853354, encodeId=12fd185335446, content=<a href='/topic/show?id=48351020537' target=_blank style='color:#2F92EE;'>#JACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=19, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10205, encryptionId=48351020537, topicName=JACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, createdName=hbwxf, createdTime=Sat Apr 23 17:16:00 CST 2016, time=2016-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1325044, encodeId=2ba01325044c4, content=<a href='/topic/show?id=96c71804b7' target=_blank style='color:#2F92EE;'>#ACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1804, encryptionId=96c71804b7, topicName=ACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e452500029, createdName=12498568m50暂无昵称, createdTime=Fri Jun 05 05:16:00 CST 2015, time=2015-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1387692, encodeId=2a01138e692e3, content=<a href='/topic/show?id=f210e72532e' target=_blank style='color:#2F92EE;'>#纤维瘤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=77253, encryptionId=f210e72532e, topicName=纤维瘤)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5fc62500009, createdName=12498474m30暂无昵称, createdTime=Fri Jun 05 05:16:00 CST 2015, time=2015-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1429402, encodeId=e00e142940231, content=<a href='/topic/show?id=bb015438221' target=_blank style='color:#2F92EE;'>#手术切除#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54382, encryptionId=bb015438221, topicName=手术切除)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cfdd4195665, createdName=s_pl2009, createdTime=Fri Jun 05 05:16:00 CST 2015, time=2015-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=25841, encodeId=f3df25841f0, content=吧, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=98961625316, createdName=12368, createdTime=Wed Jun 03 15:18:00 CST 2015, time=2015-06-03, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=2023195, encodeId=4c7d2023195bf, content=<a href='/topic/show?id=a5f45008190' target=_blank style='color:#2F92EE;'>#弹力纤维瘤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50081, encryptionId=a5f45008190, topicName=弹力纤维瘤)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=395f25, createdName=bioon1, createdTime=Wed Aug 26 07:16:00 CST 2015, time=2015-08-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2044964, encodeId=55992044964d3, content=<a href='/topic/show?id=a4d02358610' target=_blank style='color:#2F92EE;'>#乳头状#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23586, encryptionId=a4d02358610, topicName=乳头状)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ce5632, createdName=jianjun66, createdTime=Thu Oct 01 13:16:00 CST 2015, time=2015-10-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1650996, encodeId=6fc1165099636, content=<a href='/topic/show?id=2aa35090181' target=_blank style='color:#2F92EE;'>#心动图#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50901, encryptionId=2aa35090181, topicName=心动图)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8a7624121693, createdName=zhu_jun9845, createdTime=Fri Apr 08 14:16:00 CST 2016, time=2016-04-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1853354, encodeId=12fd185335446, content=<a href='/topic/show?id=48351020537' target=_blank style='color:#2F92EE;'>#JACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=19, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10205, encryptionId=48351020537, topicName=JACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, createdName=hbwxf, createdTime=Sat Apr 23 17:16:00 CST 2016, time=2016-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1325044, encodeId=2ba01325044c4, content=<a href='/topic/show?id=96c71804b7' target=_blank style='color:#2F92EE;'>#ACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1804, encryptionId=96c71804b7, topicName=ACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e452500029, createdName=12498568m50暂无昵称, createdTime=Fri Jun 05 05:16:00 CST 2015, time=2015-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1387692, encodeId=2a01138e692e3, content=<a href='/topic/show?id=f210e72532e' target=_blank style='color:#2F92EE;'>#纤维瘤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=77253, encryptionId=f210e72532e, topicName=纤维瘤)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5fc62500009, createdName=12498474m30暂无昵称, createdTime=Fri Jun 05 05:16:00 CST 2015, time=2015-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1429402, encodeId=e00e142940231, content=<a href='/topic/show?id=bb015438221' target=_blank style='color:#2F92EE;'>#手术切除#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54382, encryptionId=bb015438221, topicName=手术切除)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cfdd4195665, createdName=s_pl2009, createdTime=Fri Jun 05 05:16:00 CST 2015, time=2015-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=25841, encodeId=f3df25841f0, content=吧, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=98961625316, createdName=12368, createdTime=Wed Jun 03 15:18:00 CST 2015, time=2015-06-03, status=1, ipAttribution=)]
  7. [GetPortalCommentsPageByObjectIdResponse(id=2023195, encodeId=4c7d2023195bf, content=<a href='/topic/show?id=a5f45008190' target=_blank style='color:#2F92EE;'>#弹力纤维瘤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50081, encryptionId=a5f45008190, topicName=弹力纤维瘤)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=395f25, createdName=bioon1, createdTime=Wed Aug 26 07:16:00 CST 2015, time=2015-08-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2044964, encodeId=55992044964d3, content=<a href='/topic/show?id=a4d02358610' target=_blank style='color:#2F92EE;'>#乳头状#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23586, encryptionId=a4d02358610, topicName=乳头状)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ce5632, createdName=jianjun66, createdTime=Thu Oct 01 13:16:00 CST 2015, time=2015-10-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1650996, encodeId=6fc1165099636, content=<a href='/topic/show?id=2aa35090181' target=_blank style='color:#2F92EE;'>#心动图#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50901, encryptionId=2aa35090181, topicName=心动图)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8a7624121693, createdName=zhu_jun9845, createdTime=Fri Apr 08 14:16:00 CST 2016, time=2016-04-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1853354, encodeId=12fd185335446, content=<a href='/topic/show?id=48351020537' target=_blank style='color:#2F92EE;'>#JACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=19, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10205, encryptionId=48351020537, topicName=JACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, createdName=hbwxf, createdTime=Sat Apr 23 17:16:00 CST 2016, time=2016-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1325044, encodeId=2ba01325044c4, content=<a href='/topic/show?id=96c71804b7' target=_blank style='color:#2F92EE;'>#ACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1804, encryptionId=96c71804b7, topicName=ACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e452500029, createdName=12498568m50暂无昵称, createdTime=Fri Jun 05 05:16:00 CST 2015, time=2015-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1387692, encodeId=2a01138e692e3, content=<a href='/topic/show?id=f210e72532e' target=_blank style='color:#2F92EE;'>#纤维瘤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=77253, encryptionId=f210e72532e, topicName=纤维瘤)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5fc62500009, createdName=12498474m30暂无昵称, createdTime=Fri Jun 05 05:16:00 CST 2015, time=2015-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1429402, encodeId=e00e142940231, content=<a href='/topic/show?id=bb015438221' target=_blank style='color:#2F92EE;'>#手术切除#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54382, encryptionId=bb015438221, topicName=手术切除)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cfdd4195665, createdName=s_pl2009, createdTime=Fri Jun 05 05:16:00 CST 2015, time=2015-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=25841, encodeId=f3df25841f0, content=吧, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=98961625316, createdName=12368, createdTime=Wed Jun 03 15:18:00 CST 2015, time=2015-06-03, status=1, ipAttribution=)]
  8. [GetPortalCommentsPageByObjectIdResponse(id=2023195, encodeId=4c7d2023195bf, content=<a href='/topic/show?id=a5f45008190' target=_blank style='color:#2F92EE;'>#弹力纤维瘤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50081, encryptionId=a5f45008190, topicName=弹力纤维瘤)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=395f25, createdName=bioon1, createdTime=Wed Aug 26 07:16:00 CST 2015, time=2015-08-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2044964, encodeId=55992044964d3, content=<a href='/topic/show?id=a4d02358610' target=_blank style='color:#2F92EE;'>#乳头状#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23586, encryptionId=a4d02358610, topicName=乳头状)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ce5632, createdName=jianjun66, createdTime=Thu Oct 01 13:16:00 CST 2015, time=2015-10-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1650996, encodeId=6fc1165099636, content=<a href='/topic/show?id=2aa35090181' target=_blank style='color:#2F92EE;'>#心动图#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50901, encryptionId=2aa35090181, topicName=心动图)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8a7624121693, createdName=zhu_jun9845, createdTime=Fri Apr 08 14:16:00 CST 2016, time=2016-04-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1853354, encodeId=12fd185335446, content=<a href='/topic/show?id=48351020537' target=_blank style='color:#2F92EE;'>#JACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=19, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10205, encryptionId=48351020537, topicName=JACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, createdName=hbwxf, createdTime=Sat Apr 23 17:16:00 CST 2016, time=2016-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1325044, encodeId=2ba01325044c4, content=<a href='/topic/show?id=96c71804b7' target=_blank style='color:#2F92EE;'>#ACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1804, encryptionId=96c71804b7, topicName=ACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e452500029, createdName=12498568m50暂无昵称, createdTime=Fri Jun 05 05:16:00 CST 2015, time=2015-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1387692, encodeId=2a01138e692e3, content=<a href='/topic/show?id=f210e72532e' target=_blank style='color:#2F92EE;'>#纤维瘤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=77253, encryptionId=f210e72532e, topicName=纤维瘤)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5fc62500009, createdName=12498474m30暂无昵称, createdTime=Fri Jun 05 05:16:00 CST 2015, time=2015-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1429402, encodeId=e00e142940231, content=<a href='/topic/show?id=bb015438221' target=_blank style='color:#2F92EE;'>#手术切除#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54382, encryptionId=bb015438221, topicName=手术切除)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cfdd4195665, createdName=s_pl2009, createdTime=Fri Jun 05 05:16:00 CST 2015, time=2015-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=25841, encodeId=f3df25841f0, content=吧, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=98961625316, createdName=12368, createdTime=Wed Jun 03 15:18:00 CST 2015, time=2015-06-03, status=1, ipAttribution=)]
    2015-06-03 12368

    0