Eur J Radiol:增强CT在诊断结直肠肝转移患者化疗后肝窦阻塞综合征的价值:影像-病理相关性分析

2017-08-05 shaosai MedSci原创

肝窦阻塞综合征(SOS)是由于肝窦内皮细胞损害致肝窦流出道阻塞所引起的肝内窦性门脉高压。SOS的临床表现为疼痛性肝肿大、腹水形成等,严重的可进展为非门脉性肝硬化。摄入吡咯双烷类生物碱与器官移植是引起SOS的两大常见原因。

肝窦阻塞综合征(SOS)是由于肝窦内皮细胞损害致肝窦流出道阻塞所引起的肝内窦性门脉高压。SOS的临床表现为疼痛性肝肿大、腹水形成等,严重的可进展为非门脉性肝硬化。摄入吡咯双烷类生物碱与器官移植是引起SOS的两大常见原因。腹部增强CT或MRI检查在门脉期与延迟期可清楚显示造影受阻于门脉分支末端区而未能进入肝叶、段静脉,导致肝静脉不显影,具有诊断价值。肝组织学的表现为肝组织淤血,肝窦扩张,尤其是肝小静脉壁增厚、纤维化、管腔狭窄甚至闭塞,这是该病的典型表现。SOS可为结直肠肝转移(CRLM)的并发症。本研究旨在评估CT诊断CRLM术前接受新辅助化疗(NC)患者SOS的价值,并与病理结果相对照,并将结果发表在Eur J Radiol上。本研究纳入了自2011-201667例在CRLM肝切除术前接受NC的患者并行CT增强扫描。阳性诊断和SOS的程度结果是建立在3位病理科医生对切片达成共识之上的。由两位放射科医生独立对术前CT图像进行分析,并对SOS的征象进行总结。利用单变量分析和多变量logistic回归分析CT征象和病理结果的相关性,从而得出SOS的典型征象。结果为,共有29例患者(43%)并

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    2018-06-26 tomyang96
  4. 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  5. 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  6. 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  7. 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createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzaiabIFicf63hKvVMjL6aJlx4yX4UcXmzX9DyibCRcicq0QtCRWMaQKh8MYjE1D3EKUBopgiaGWYuqbeR/0, createdBy=0c2b1999806, createdName=三生有幸9135, createdTime=Sat Aug 05 15:46:12 CST 2017, time=2017-08-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=230368, encodeId=5f6f23036877, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Sat Aug 05 12:58:29 CST 2017, time=2017-08-05, status=1, ipAttribution=)]
    2017-08-05 三生有幸9135

    学习一下谢谢分享

    0

  10. 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01:08:00 CST 2017, time=2017-08-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1523541, encodeId=120615235418a, content=<a href='/topic/show?id=f6f1e2533e3' target=_blank style='color:#2F92EE;'>#相关性分析#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72533, encryptionId=f6f1e2533e3, topicName=相关性分析)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ad8f11536374, createdName=anminleiryan, createdTime=Mon Aug 07 01:08:00 CST 2017, time=2017-08-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=230378, encodeId=a3e72303e82b, content=学习一下谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzaiabIFicf63hKvVMjL6aJlx4yX4UcXmzX9DyibCRcicq0QtCRWMaQKh8MYjE1D3EKUBopgiaGWYuqbeR/0, createdBy=0c2b1999806, createdName=三生有幸9135, createdTime=Sat Aug 05 15:46:12 CST 2017, time=2017-08-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=230368, encodeId=5f6f23036877, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Sat Aug 05 12:58:29 CST 2017, time=2017-08-05, status=1, ipAttribution=)]
    2017-08-05 清风拂面

    学习了,谢谢分享

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