Eur Heart J:比较ATRIA, CHADS2, 和HA2DS2-VASc卒中风险评分

2016-03-09 MedSci MedSci原创

    <span style="font-family:"微软雅黑","sans-serif";mso-ascii-font-family: Tahoma;mso-hansi-font-family:Tahoma">原始出处: Aspberg S ,Chang Y, Atterman A,et al,Comp

更好的卒中风险预测对于优化房颤患者的抗凝选择是有必要的。ATRIA 卒中风险评分(ATRIA)经两个大型的加利福利亚社区房颤组开发并证实。我们通过瑞典国家房颤人群(SAF)比较了ATRIA, CHADS2,和 CHA2DS2-VASc评分的表现。


我们检查了所有瑞典住院病人,或随访了医院门诊从2005年7月到2010年12月诊断的房颤患者。从综合国家数据库确定变量。通过C指数(C)和净重新分类指数(NRI)评估风险评分。总共观察到11053例急性缺血性卒中,平均发生率为3.2%/年,高于加利福利亚人群的2%/年。使用整点分数, ATRIA有良好的C指数,0.708 (0.704-0.713),显著优于CHADS2 0.690 (0.685-0.695) 或 CHA2DS2-VASc 0.694(0.690-0.700)。使用分割点表示低/中/高的风险,C指数下降,但ATRIA仍最高。净重新分类指数支持ATRIA 0.16 (0.14-0.17) vs. CHADS2 and 0.21
(0.20-0.23) vs. CHA2DS2-VASc。当选择分割点来更好的匹配人群卒中比例时,净重新分类指数下降。

在这个SAF中,ATRIA评分预测缺血性卒中风险优于CHADS2 或 CHA2DS2-VASc。

原始出处:

Aspberg S ,Chang Y, Atterman A,et al,Comparison
of the ATRIA, CHADS2, and HA2DS2-VASc stroke risk scores in
predicting ischaemic stroke in a large Swedish cohort of patients with atrial
fibrillation.
Eur Heart J. 2016 Mar 3. pii: ehw077.


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    2016-07-26 quxin068
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    2016-03-22 1de304d2m86(暂无匿称)

    学习了,好

    0

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    2016-03-11 zhaojie88
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    2016-03-11 slcumt
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    2016-03-10 dhzzm

    学习了,有意思

    0