Diabetes Care:2型糖尿病合并抑郁症和焦虑症状对死亡率风险有何影响?

2017-01-15 xing.T MedSci原创

焦虑症状可以独立于抑郁症症状,除了减弱抑郁症状和这些个体死亡率之间相关性的抑郁症症状外,影响2型糖尿病患者的死亡率风险。

抑郁症与2型糖尿病患者死亡率增加密切相关。尽管焦虑和抑郁症同时出现的发生率较高,但是对于2型糖尿病患者共患焦虑症相关的死亡风险知之甚少。近日,糖尿病领域权威杂志Diabetes Care发表了一篇研究文章,这项研究旨在明确过量的死亡率风险与2型糖尿病伴发的抑郁和/或焦虑症状相关。

研究人员使用来自于Nord-Trøndelag健康研究(HUNT 2)的64177名挪威人的数据,该研究与挪威死亡原因登记中心相联系。研究人员评估了在1995年至2013年期间参与调查人群的全因死亡率。研究者使用Cox比例风险模型评估了18岁以上与2型糖尿病相关的死亡率风险,以及对基线水平存在的伴发情感症状进行评估。

在该研究结果中,研究人员得出三中清晰的模式,首先,糖尿病患者在存在抑郁症或焦虑,或两者均有的情况下,死亡率风险明显增加。其次,伴有焦虑症状的患者死亡率风险最低,共患有抑郁和焦虑的患者死亡率风险较高,抑郁症患者死亡率风险最高。最后,与抑郁症和焦虑相关的过量死亡风险在男性糖尿病患者中可以观察到,而在女性中没有观察到。在只有抑郁症症状的男性糖尿病患者中死亡的风险最高(风险比为3.47,95%可信区间为1.96-6.14)。

该研究提供的证据表明,焦虑症状可以独立于抑郁症症状,除了减弱抑郁症状和这些个体死亡率之间相关性的抑郁症症状外,影响2型糖尿病患者的死亡率风险。

原始出处:


Kiyuri Naicker, et al. Type 2 Diabetes and Comorbid Symptoms of Depression and Anxiety: Longitudinal Associations With Mortality Risk. Diabetes Care .2017 Jan. 

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    2017-01-16 三生有幸9135

    明确过量的死亡率风险与2型糖尿病伴发的抑郁和/或焦虑症状相关。

    0

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    2017-01-16 thlabcde

    好东西学习了!

    0

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    2017-01-16 yafeiliutjh

    差的远呀

    0

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