J Thromb Haemost:妊娠期或产后早期胸部CT对早发乳腺癌风险的影响!

2018-02-19 xing.T MedSci原创

由此可见,在妊娠期或产后期暴露于胸部CT与母亲乳腺癌短期风险增加无关。而长期风险需要进一步研究。

妊娠期或产后期直接暴露于胸部计算机断层扫描(CT)辐射会增加患乳腺癌的风险。近日,血栓和凝血疾病权威杂志Journal of Thrombosis and Haemostasis上发表了一篇研究文章,研究人员旨在评估了这些时期胸部CT暴露后对母体乳腺癌的短期风险。

研究人员采用加拿大安大略全民保健数据库确定了1995-2014年期间所有分娩患者进行了一项回顾性队列研究。该研究的主要暴露因素为在妊娠期间或产后≤42天进行的胸部CT。每一个参与者都与未经胸部CT或VQ扫描的妊娠女性相比较。该研究的主要结局为分娩后366天后新诊断的乳腺癌。

该研究共有5859名妊娠女性暴露于胸部CT,4075名妊娠女性暴露于VQ扫描,1292059名妊娠女性均未暴露。从分娩后一年起,随访的中位时间分别为5.9、7.3和11.1年。共有10129名妇女被诊断为乳腺癌,其中9039例(89.2%)≤50岁。暴露于胸部CT女性有27例乳腺癌新发病例(7.1例每10000人每年) vs. 未暴露女性有10080例乳腺癌新发病例(7例每10000人每年),调整后的风险比为1.17(95%可信区间为0.80-1.70)。继VQ扫描暴露,乳腺癌的发病率为7例每10000人每年,调整后的风险比为1.23(95%可信区间为0.81-1.87),相比于未暴露的队列。

由此可见,在妊娠期或产后期暴露于胸部CT与母亲乳腺癌短期风险增加无关。而长期风险需要进一步研究。

原始出处:


Kirsteen R. Burton,et al. Risk of early onset breast cancer among women exposed to thoracic computed tomography in pregnancy or early postpartum.Journal of Thrombosis and Haemostasis.2018. http://onlinelibrary.wiley.com/doi/10.1111/jth.13980/full

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    2018-11-29 changfy
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createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/o7RpnhFvZBIzqjGrBgqI0uzRLOMECqe0mUpMfFjUzOgITVyDyibNibupQsIC9cX2wJO3c8HCDxjD21MIQxtbI9Lg/132, createdBy=f64d2300444, createdName=lq1768, createdTime=Wed Feb 21 13:35:00 CST 2018, time=2018-02-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1251103, encodeId=7268125110387, content=<a href='/topic/show?id=90494486837' target=_blank style='color:#2F92EE;'>#妊娠期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44868, encryptionId=90494486837, topicName=妊娠期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0b7c20, createdName=wjcjjian, createdTime=Wed Feb 21 13:35:00 CST 2018, time=2018-02-21, status=1, ipAttribution=)]
    2018-04-26 sjq027
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    2018-05-06 zwjnj2

    好好学习认真学习天天向上

    0

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createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/o7RpnhFvZBIzqjGrBgqI0uzRLOMECqe0mUpMfFjUzOgITVyDyibNibupQsIC9cX2wJO3c8HCDxjD21MIQxtbI9Lg/132, createdBy=f64d2300444, createdName=lq1768, createdTime=Wed Feb 21 13:35:00 CST 2018, time=2018-02-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1251103, encodeId=7268125110387, content=<a href='/topic/show?id=90494486837' target=_blank style='color:#2F92EE;'>#妊娠期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44868, encryptionId=90494486837, topicName=妊娠期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0b7c20, createdName=wjcjjian, createdTime=Wed Feb 21 13:35:00 CST 2018, time=2018-02-21, status=1, ipAttribution=)]
    2018-04-22 zwjnj2

    好好学习学习天天向上

    0

  6. 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    2018-03-04 1e145228m78(暂无匿称)

    学习了.谢谢作者分享!

    0

  7. 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    2018-02-26 zwjnj2

    好好好好学习学习学习

    0

  9. 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    2018-02-21 lq1768
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    2018-02-21 wjcjjian

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