JAHA:我国的颈动脉粥样硬化情况!

2018-04-07 xing.T MedSci原创

由此可见,在中国的中老年人群中CA普遍存在。这一结果显示关注动脉粥样硬化进展的一级预防具有潜在的临床重要性。

颈动脉粥样硬化(CA)可反映全身血管疾病相关的全身动脉粥样硬化标志。在一个全国性的具有代表性的人群样本中,数据仅限于颈动脉病变的流行病学。近日,心血管疾病领域权威杂志JAHA上发表了一篇研究文章,研究人员的目的是基于中国的一项全国调查来评估通过颈动脉超声检查发现的CA患病率及相关危险因素。

研究人员共纳入了107095名来自于中国国家卒中预防项目的超过40岁的且接受颈动脉超声检查居民。进行过颈动脉内膜切除术或颈动脉支架置入术的患者以及发生卒中或冠心病患者排除在外。来自于84880名参与者的数据被纳入分析。CA被定义为–颈动脉内膜中层厚度(IMT)增厚≥1mm或存在斑块。

在84880名参与者中,46.4%为男性,平均年龄为60.7±10.3岁。CA的标准化患病率总体为36.2%,随着年龄的增长而增加,男性高于女性。居住在农村地区的参与者CA的患病率高于城市地区。约26.5%的受试者IMT增加,13.9%的受试者存在斑块。IMT增厚、斑块和狭窄的患者存在年龄相关的增加。在多元logistic回归分析中,老年、男性、农村居民、吸烟、饮酒、身体活动较少、肥胖、高血压糖尿病和血脂异常与CA有关。

由此可见,在中国的中老年人群中CA普遍存在。这一结果显示关注动脉粥样硬化进展的一级预防具有潜在的临床重要性。

原始出处:


Xiaojun Wang,et al. Carotid Atherosclerosis Detected by Ultrasonography: A National Cross‐Sectional Study, JAHA.2018. https://doi.org/10.1161/JAHA.118.008701

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    2018-04-09 周周人

    学习.一

    0

  4. 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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Sat Apr 07 18:09:30 CST 2018, time=2018-04-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=303614, encodeId=dcc9303614e6, content=不容乐观啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKibA62IFMeUJEmSyIe8DvYFeERuOsfrRd8iano7nENqQU1dRR3tqeQOUL3eqgYgEZRT2t2iaEsib0JEw/132, createdBy=66771693911, createdName=易水河, createdTime=Sat Apr 07 17:46:20 CST 2018, time=2018-04-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=303599, encodeId=1e9d30359999, content=认真学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLCSnicyibWfBTADUOjice1wnN8fal65AictjJzXuPFfriafV33NLPOQ6DiahyynUTFBZIrsPTAKwxp2ZbwlshWlCPTEvKiaaibEmr478vA/0, createdBy=3a912053405, createdName=137****8002, createdTime=Sat Apr 07 15:40:09 CST 2018, time=2018-04-07, status=1, ipAttribution=)]
    2018-04-09 zhaohui6731
  5. 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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Sat Apr 07 18:09:30 CST 2018, time=2018-04-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=303614, encodeId=dcc9303614e6, content=不容乐观啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKibA62IFMeUJEmSyIe8DvYFeERuOsfrRd8iano7nENqQU1dRR3tqeQOUL3eqgYgEZRT2t2iaEsib0JEw/132, createdBy=66771693911, createdName=易水河, createdTime=Sat Apr 07 17:46:20 CST 2018, time=2018-04-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=303599, encodeId=1e9d30359999, content=认真学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLCSnicyibWfBTADUOjice1wnN8fal65AictjJzXuPFfriafV33NLPOQ6DiahyynUTFBZIrsPTAKwxp2ZbwlshWlCPTEvKiaaibEmr478vA/0, createdBy=3a912053405, createdName=137****8002, createdTime=Sat Apr 07 15:40:09 CST 2018, time=2018-04-07, status=1, ipAttribution=)]
  6. 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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Sat Apr 07 18:09:30 CST 2018, time=2018-04-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=303614, encodeId=dcc9303614e6, content=不容乐观啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKibA62IFMeUJEmSyIe8DvYFeERuOsfrRd8iano7nENqQU1dRR3tqeQOUL3eqgYgEZRT2t2iaEsib0JEw/132, createdBy=66771693911, createdName=易水河, createdTime=Sat Apr 07 17:46:20 CST 2018, time=2018-04-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=303599, encodeId=1e9d30359999, content=认真学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLCSnicyibWfBTADUOjice1wnN8fal65AictjJzXuPFfriafV33NLPOQ6DiahyynUTFBZIrsPTAKwxp2ZbwlshWlCPTEvKiaaibEmr478vA/0, createdBy=3a912053405, createdName=137****8002, createdTime=Sat Apr 07 15:40:09 CST 2018, time=2018-04-07, status=1, ipAttribution=)]
    2018-04-07 lofter

    学习了感谢分享

    0

  7. 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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Sat Apr 07 18:09:30 CST 2018, time=2018-04-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=303614, encodeId=dcc9303614e6, content=不容乐观啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKibA62IFMeUJEmSyIe8DvYFeERuOsfrRd8iano7nENqQU1dRR3tqeQOUL3eqgYgEZRT2t2iaEsib0JEw/132, createdBy=66771693911, createdName=易水河, createdTime=Sat Apr 07 17:46:20 CST 2018, time=2018-04-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=303599, encodeId=1e9d30359999, content=认真学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLCSnicyibWfBTADUOjice1wnN8fal65AictjJzXuPFfriafV33NLPOQ6DiahyynUTFBZIrsPTAKwxp2ZbwlshWlCPTEvKiaaibEmr478vA/0, createdBy=3a912053405, createdName=137****8002, createdTime=Sat Apr 07 15:40:09 CST 2018, time=2018-04-07, status=1, ipAttribution=)]
    2018-04-07 131****1460

    学习了受益匪浅

    0

  8. 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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Sat Apr 07 18:09:30 CST 2018, time=2018-04-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=303614, encodeId=dcc9303614e6, content=不容乐观啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKibA62IFMeUJEmSyIe8DvYFeERuOsfrRd8iano7nENqQU1dRR3tqeQOUL3eqgYgEZRT2t2iaEsib0JEw/132, createdBy=66771693911, createdName=易水河, createdTime=Sat Apr 07 17:46:20 CST 2018, time=2018-04-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=303599, encodeId=1e9d30359999, content=认真学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLCSnicyibWfBTADUOjice1wnN8fal65AictjJzXuPFfriafV33NLPOQ6DiahyynUTFBZIrsPTAKwxp2ZbwlshWlCPTEvKiaaibEmr478vA/0, createdBy=3a912053405, createdName=137****8002, createdTime=Sat Apr 07 15:40:09 CST 2018, time=2018-04-07, status=1, ipAttribution=)]
    2018-04-07 1ddf0692m34(暂无匿称)

    学习了.谢谢分享

    0

  9. 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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Sat Apr 07 18:09:30 CST 2018, time=2018-04-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=303614, encodeId=dcc9303614e6, content=不容乐观啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKibA62IFMeUJEmSyIe8DvYFeERuOsfrRd8iano7nENqQU1dRR3tqeQOUL3eqgYgEZRT2t2iaEsib0JEw/132, createdBy=66771693911, createdName=易水河, createdTime=Sat Apr 07 17:46:20 CST 2018, time=2018-04-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=303599, encodeId=1e9d30359999, content=认真学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLCSnicyibWfBTADUOjice1wnN8fal65AictjJzXuPFfriafV33NLPOQ6DiahyynUTFBZIrsPTAKwxp2ZbwlshWlCPTEvKiaaibEmr478vA/0, createdBy=3a912053405, createdName=137****8002, createdTime=Sat Apr 07 15:40:09 CST 2018, time=2018-04-07, status=1, ipAttribution=)]
    2018-04-07 易水河

    不容乐观啊

    0

  10. 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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Sat Apr 07 18:09:30 CST 2018, time=2018-04-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=303614, encodeId=dcc9303614e6, content=不容乐观啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKibA62IFMeUJEmSyIe8DvYFeERuOsfrRd8iano7nENqQU1dRR3tqeQOUL3eqgYgEZRT2t2iaEsib0JEw/132, createdBy=66771693911, createdName=易水河, createdTime=Sat Apr 07 17:46:20 CST 2018, time=2018-04-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=303599, encodeId=1e9d30359999, content=认真学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLCSnicyibWfBTADUOjice1wnN8fal65AictjJzXuPFfriafV33NLPOQ6DiahyynUTFBZIrsPTAKwxp2ZbwlshWlCPTEvKiaaibEmr478vA/0, createdBy=3a912053405, createdName=137****8002, createdTime=Sat Apr 07 15:40:09 CST 2018, time=2018-04-07, status=1, ipAttribution=)]
    2018-04-07 137****8002

    认真学习了!

    0

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由此可见,亚临床颈动脉粥样硬化与阿尔茨海默病高危人群认知障碍相关。针对动脉粥样硬化早期的干预可能会改变认知老化。

ATVB:家族性血脂异常患者血清总胆红素水平与颈动脉粥样硬化的关系!

由此可见,在家族性和非家族性血脂异常患者中,TB与颈动脉斑块负担呈独立的负相关。这些发现支持使用TB作为动脉粥样硬化高危人群的生物标记物。

JAHA:镉、颈动脉粥样硬化与缺血性卒中发生率之间的相关性分析!

由此可见,血浆中镉浓度与缺血性卒中的发生既独立相关,又可与颈动脉斑块协同作用对其产生影响。这支持了镉促进颈动脉斑块易损性的假设,从而增加了斑块破裂和缺血性卒中的风险。

Int J Cardiol:牙周病或可导致颈动脉粥样硬化的发生——meta分析

关于牙周病与颈动脉粥样硬化之间的关系主要限于单中心研究,而且牙周病是否是颈动脉粥样硬化的一个独立危险因素仍尚未清楚。该项荟萃分析旨在评估牙周病与颈动脉粥样硬化之间的关系。

Eur J Prev Cardiol:可怕!这么高比例的中国成年人有颈动脉斑块

过去几十年,尽管中国人的寿命大幅增长,但心血管疾病死亡率也在增在。研究中国人群的颈动脉粥样硬化流行病学对未来了解心血管疾病风险意义重大。2017年4月,发表在《Eur J Prev Cardiol》的一项研究显示,大约三分之一的中国成年人有颈动脉斑块。同欧洲人群相比,中国人的颈动脉粥样硬化进展率随年龄增加更快。请看本期多学科讨论组临床药师各抒己见为您梳理本文看点——背景:基于人群的颈动脉粥样硬化超

Stroke:蔬菜硝酸盐摄入量与老年妇女颈动脉粥样硬化及缺血性脑血管病的关系!

独立于其他危险因素,较高的蔬菜硝酸盐摄入量与较低的CCA-IMT和较低的缺血性脑血管病事件风险相关。