J Interv Card Electrophysiol:半数起搏器植入术后患者TnT会短暂升高,对预后无明显影响

2017-04-26 朱柳媛 中国循环杂志

在临床实践中,可能有医生会发现,有些患者在植入永久起搏器后心脏肌钙蛋白T(TnT)水平会升高。这是否代表心脏有受损?是否需要处理?

临床实践中,可能有医生会发现,有些患者在植入永久起搏器后心脏肌钙蛋白T(TnT)水平会升高。这是否代表心脏有受损?是否需要处理?

近期,复旦大学附属中山医院陈学颖等公布的一项研究表明,55.6%的患者在起搏器植入术后6 h出现肌钙蛋白T升高,但这种升高是一过性的,24 h小时左右可恢复正常,并不会导致并发症或严重心脏事件风险增加。

在该研究中,374例植入永久起搏器的患者中,208例(55.6%)在术后6小时出现肌钙蛋白T升高,其中29例(7.8%)的患者肌钙蛋白T仅达到微小心肌损伤阈值,即>0.09 ng/ml。

所有患者术前的中位肌钙蛋白T水平为0.012 ng/ml,术后6小时达到0.032 ng/ml,但术后24小时时即已经降至0.019 ng/ml。

研究者对患者进行为期1年的随访后发现,在术后6小时出现肌钙蛋白T升高的患者中,导线移位、囊袋感染、气胸、血胸和静脉血栓形成等并发症的发生风险并未增加,因心衰、冠心病、心律失常住院和心血管死亡等严重心脏不良事件风险也未升高。

Logistic回归分析显示,校正年龄、起搏器类型、右室导线位置(RVA或RVOT)、心功能和左室收缩末期内径等因素后,性别、基线N末端B型利钠肽原(NT-pro-BNP)水平、左室射血分数、估算肾小球滤过率(eGFR)和透视时间都是肌钙蛋白T升高的独立预测因素。

原始出处:

Chen X, Yu Z, Bai J, et al. TroponinT elevation after permanent pacemaker implantation. J Interv Card Electrophysiol. 2017 Apr 18.

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    2017-04-28 HNYYM
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    2017-04-28 jiyangfei
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    2017-04-26 1e1a50a1m36(暂无匿称)

    患者在植入永久起搏器后心脏肌钙蛋白T(TnT)水平会升高

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