Nat Bio Engin :准确测试细胞年龄的新方法,把疾病扼杀在摇篮里!

2017-07-12 Heather_z727 来宝网

人们都知道自己的年龄,但是细胞的年龄呢?他们与实际年龄相同吗,更老还是更年期,这重要吗?



预测细胞年龄的准确方法,帮助预防老年疾病】人们都知道自己的年龄,但是细胞的年龄呢?他们与实际年龄相同吗,更老还是更年期,这重要吗?

来自约翰霍普金斯大学的研究小组展开了研究,他们开发了一种方法能够准确确定细胞功能,此举可以帮助临床医生评估和推荐延迟衰老的方法,以及改善一些疾病的治疗方法,包括皮肤匹配移植,伤口愈合预测等。

此次研究是一项跨学科的研究,来自约翰霍普金斯大学,耶鲁大学和美国国家癌症研究所的美国国立卫生研究院的研究人员们设计一个系统,通过计算分析可以测量细胞和分子功能的各种因素。从这些信息中,研究人员可以更准确测量细胞年龄。完整的研究报告发表于最新一期的《自然生物医学》杂志上。报道中详细描述了细胞老化的过程。此次研究结果表明,细胞的生物物理特性,如细胞运动和结构特点。

研究人员表示:“我们结合一些经典的生物分子老化的特点,试图进一步阐明衰老细胞的生物物理特性的作用,试图理解衰老DNA遗传特征。”-

此次研究的目的旨在纠正细胞生物物理属性的遗漏,包括因素细胞的能力,保持灵活性的能力等,这一研究对理解与年龄增长有关的生理层面变化,如肺活量的减少,握力和动脉中平均压力的变化等,都有着积极的作用。比如,通过细胞年龄的准确判断来推测伤口愈合的速度。

原始出处:

Jude M. Phillip et al, Biophysical and biomolecular determination of cellular age in humans, Nature Biomedical Engineering (2017). DOI: 10.1038/s41551-017-0093.

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    2017-09-26 liye789132251
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    2018-01-17 spoonycyy
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    2017-10-12 sunylz
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  6. [GetPortalCommentsPageByObjectIdResponse(id=1882280, encodeId=da131882280f6, content=<a href='/topic/show?id=3b2112532d8' target=_blank style='color:#2F92EE;'>#Nat#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12532, encryptionId=3b2112532d8, topicName=Nat)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2e6f107, createdName=liye789132251, createdTime=Tue Sep 26 23:58:00 CST 2017, time=2017-09-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2081383, encodeId=9daa20813830c, content=<a href='/topic/show?id=57406e8506' target=_blank style='color:#2F92EE;'>#Eng#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6785, encryptionId=57406e8506, topicName=Eng)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3516494, createdName=spoonycyy, createdTime=Wed Jan 17 04:58:00 CST 2018, time=2018-01-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1785345, encodeId=c6751e8534540, content=<a href='/topic/show?id=0a9c6e87ef' target=_blank style='color:#2F92EE;'>#Engin#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6787, encryptionId=0a9c6e87ef, topicName=Engin)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3fc52500170, createdName=12498cbcm00(暂无昵称), createdTime=Tue Jan 23 18:58:00 CST 2018, time=2018-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1917566, encodeId=8672191e566ca, content=<a href='/topic/show?id=4f26341994' target=_blank style='color:#2F92EE;'>#Bio#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3419, encryptionId=4f26341994, topicName=Bio)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=12de429, createdName=sunylz, createdTime=Thu Oct 12 01:58:00 CST 2017, time=2017-10-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1903245, encodeId=5aed1903245d4, content=<a href='/topic/show?id=e1b0583884b' target=_blank style='color:#2F92EE;'>#新方法#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58388, encryptionId=e1b0583884b, topicName=新方法)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c22f171, createdName=kord1982, createdTime=Sun May 06 22:58:00 CST 2018, time=2018-05-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=221533, encodeId=bc5722153314, content=实时紧跟科技前沿,小编们辛苦了, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5KynZWiaZcw1J0lWhzLtT6ukInjVSRV4un6UrPrs68caGt3cNk2qhwctOqMFPWlvwF4wkvtn7bTIOQ/0, createdBy=cca998055, createdName=nannanxyy, createdTime=Wed Jul 12 22:18:24 CST 2017, time=2017-07-12, status=1, ipAttribution=)]
    2017-07-12 nannanxyy

    实时紧跟科技前沿,小编们辛苦了

    0