Lancet子刊:互联网CBT疗法是否能给抑郁症患者带来更好的疗效?

2021-06-01 MedSci原创 MedSci原创

认知行为疗法(CBT)是旨在改善心理健康的一种心理社会干预 。

认知行为疗法(CBT)是旨在改善心理健康的一种心理社会干预 。CBT专注于挑战和改变无助的认知扭曲(例如思想,信念和态度)和行为,改善情绪调节,以及针对解决当前问题的个人应对策略的发展。

最初,它被设计用于治疗抑郁症,但其用途已扩展到包括治疗许多心理健康状况,包括焦虑症。CBT包括使用基于证据的技术和策略来治疗已定义的心理病理的许多认知或行为心理治疗。

随着网络的普及,互联网认知行为疗法(iCBT)逐渐被认为是一种可行的治疗抑郁症的CBT实施形式。然而,iCBT方案包括通过不同的传递方式进行广泛的认知和行为技能的训练,目前仍不清楚这些内容中哪些更有效,对谁更有效。

近日,来自日本东京大学的专家对iCBT治疗抑郁症的试验进行系统回顾,结果发表在Lancet Psychiatry杂志上。研究人员在PubMed、PsycINFO、Embase和Cochrane图书馆搜索了到2019年1月1日发表的随机对照试验(RCTs),这些试验比较了任何形式的iCBT与另一种或对照条件在成人抑郁症急性治疗中的情况。

共确定了76项RCTs,包括48项提供个体参与者数据的试验(11704名参与者)和28项提供总体数据的试验(6474名参与者)。参与者的平均年龄为42.0岁,12406人(71%)为女性。

总得来说,证据表明,行为激活可能是有益的(iMD-1.83[95% CrI: -2.90至-0-80]),但放松可能是有害的(1. 20[95%CrI: 0.17至2.27])。其中,基线严重程度成为终点抑郁症的最强预后因素。

人工和自动鼓励的结合减少了治疗的退出。在大多数纳入的研究中,随机化过程、结果数据缺失或报告结果选择的偏倚风险较低,偏离预期干预措施的风险不确定,结果测量的偏倚风险较高。各项研究及其组成部分之间存在着中度至高度的异质性。

由此可见,iCBT套餐的潜在帮助、较少帮助或有害的成分和交付形式。旨在有效和高效的iCBT套餐可能会选择包括有益的成分,并排除可能有害的成分。网络应用可以促进治疗师和患者共同决策,选择他们喜欢的iCBT套餐。

 

参考文献:

Dismantling, optimising, and personalising internet cognitive behavioural therapy for depression: a systematic review and component network meta-analysis using individual participant data. DOI:https://doi.org/10.1016/S2215-0366(21)00077-8

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    2022-04-21 howi
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  5. [GetPortalCommentsPageByObjectIdResponse(id=2068724, encodeId=3b8a2068e246f, content=<a href='/topic/show?id=c907241315a' target=_blank style='color:#2F92EE;'>#互联网CBT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=24131, encryptionId=c907241315a, topicName=互联网CBT)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=19ad38, createdName=lq1767, createdTime=Mon Mar 14 19:11:19 CST 2022, time=2022-03-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1988611, encodeId=778b1988611f0, content=<a href='/topic/show?id=1fe2549e72e' target=_blank style='color:#2F92EE;'>#抑郁症患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54977, encryptionId=1fe2549e72e, topicName=抑郁症患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ce68183, createdName=xiongke010, createdTime=Wed Aug 25 15:11:19 CST 2021, time=2021-08-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1831195, encodeId=27d51831195c2, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Thu Apr 21 23:11:19 CST 2022, time=2022-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1274365, encodeId=133012e4365df, content=<a href='/topic/show?id=04fd241222d' target=_blank style='color:#2F92EE;'>#互联网#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=24122, encryptionId=04fd241222d, topicName=互联网)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2726119, createdName=july_975, createdTime=Thu Jun 03 14:11:19 CST 2021, time=2021-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1534032, encodeId=f95f1534032c4, content=<a href='/topic/show?id=354a4186d9' target=_blank style='color:#2F92EE;'>#CBT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4186, encryptionId=354a4186d9, topicName=CBT)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=517912514553, createdName=gds2013, createdTime=Thu Jun 03 14:11:19 CST 2021, time=2021-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1032945, encodeId=9b9e10329459b, content=谢谢梅斯提供这么好的信息,学到很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=内科新手, createdTime=Wed Jun 02 02:11:19 CST 2021, time=2021-06-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1034344, encodeId=a323103434459, content=顶刊就是不一样,质量很高,内容精彩!学到很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=goodbing, createdTime=Wed Jun 02 02:11:19 CST 2021, time=2021-06-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=970189, encodeId=1dcc9e0189d8, content=棒棒, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=aa065439405, createdName=ms7000001745072248, createdTime=Tue Jun 01 23:16:32 CST 2021, time=2021-06-01, status=1, ipAttribution=)]
    2021-06-03 gds2013
  6. [GetPortalCommentsPageByObjectIdResponse(id=2068724, encodeId=3b8a2068e246f, content=<a href='/topic/show?id=c907241315a' target=_blank style='color:#2F92EE;'>#互联网CBT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=24131, encryptionId=c907241315a, topicName=互联网CBT)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=19ad38, createdName=lq1767, createdTime=Mon Mar 14 19:11:19 CST 2022, time=2022-03-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1988611, encodeId=778b1988611f0, content=<a href='/topic/show?id=1fe2549e72e' target=_blank style='color:#2F92EE;'>#抑郁症患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54977, encryptionId=1fe2549e72e, topicName=抑郁症患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ce68183, createdName=xiongke010, createdTime=Wed Aug 25 15:11:19 CST 2021, time=2021-08-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1831195, encodeId=27d51831195c2, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Thu Apr 21 23:11:19 CST 2022, time=2022-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1274365, encodeId=133012e4365df, content=<a href='/topic/show?id=04fd241222d' target=_blank style='color:#2F92EE;'>#互联网#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=24122, encryptionId=04fd241222d, topicName=互联网)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2726119, createdName=july_975, createdTime=Thu Jun 03 14:11:19 CST 2021, time=2021-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1534032, encodeId=f95f1534032c4, content=<a href='/topic/show?id=354a4186d9' target=_blank style='color:#2F92EE;'>#CBT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4186, encryptionId=354a4186d9, topicName=CBT)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=517912514553, createdName=gds2013, createdTime=Thu Jun 03 14:11:19 CST 2021, time=2021-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1032945, encodeId=9b9e10329459b, content=谢谢梅斯提供这么好的信息,学到很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=内科新手, createdTime=Wed Jun 02 02:11:19 CST 2021, time=2021-06-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1034344, encodeId=a323103434459, content=顶刊就是不一样,质量很高,内容精彩!学到很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=goodbing, createdTime=Wed Jun 02 02:11:19 CST 2021, time=2021-06-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=970189, encodeId=1dcc9e0189d8, content=棒棒, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=aa065439405, createdName=ms7000001745072248, createdTime=Tue Jun 01 23:16:32 CST 2021, time=2021-06-01, status=1, ipAttribution=)]
    2021-06-02 内科新手

    谢谢梅斯提供这么好的信息,学到很多

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=2068724, encodeId=3b8a2068e246f, content=<a href='/topic/show?id=c907241315a' target=_blank style='color:#2F92EE;'>#互联网CBT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=24131, encryptionId=c907241315a, topicName=互联网CBT)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=19ad38, createdName=lq1767, createdTime=Mon Mar 14 19:11:19 CST 2022, time=2022-03-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1988611, encodeId=778b1988611f0, content=<a href='/topic/show?id=1fe2549e72e' target=_blank style='color:#2F92EE;'>#抑郁症患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54977, encryptionId=1fe2549e72e, topicName=抑郁症患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ce68183, createdName=xiongke010, createdTime=Wed Aug 25 15:11:19 CST 2021, time=2021-08-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1831195, encodeId=27d51831195c2, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Thu Apr 21 23:11:19 CST 2022, time=2022-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1274365, encodeId=133012e4365df, content=<a href='/topic/show?id=04fd241222d' target=_blank style='color:#2F92EE;'>#互联网#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=24122, encryptionId=04fd241222d, topicName=互联网)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2726119, createdName=july_975, createdTime=Thu Jun 03 14:11:19 CST 2021, time=2021-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1534032, encodeId=f95f1534032c4, content=<a href='/topic/show?id=354a4186d9' target=_blank style='color:#2F92EE;'>#CBT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4186, encryptionId=354a4186d9, topicName=CBT)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=517912514553, createdName=gds2013, createdTime=Thu Jun 03 14:11:19 CST 2021, time=2021-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1032945, encodeId=9b9e10329459b, content=谢谢梅斯提供这么好的信息,学到很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=内科新手, createdTime=Wed Jun 02 02:11:19 CST 2021, time=2021-06-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1034344, encodeId=a323103434459, content=顶刊就是不一样,质量很高,内容精彩!学到很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=goodbing, createdTime=Wed Jun 02 02:11:19 CST 2021, time=2021-06-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=970189, encodeId=1dcc9e0189d8, content=棒棒, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=aa065439405, createdName=ms7000001745072248, createdTime=Tue Jun 01 23:16:32 CST 2021, time=2021-06-01, status=1, ipAttribution=)]
    2021-06-02 goodbing

    顶刊就是不一样,质量很高,内容精彩!学到很多

    0

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    2021-06-01 ms7000001745072248

    棒棒

    0

拓展阅读

Am J Gastroenterol:互联网CBT治疗可以改善青少年IBS

本研究的目的是,评估基于行为暴露的互联网认知行为疗法(CBT)对青少年肠易激综合征(IBS)的疗效。 符合罗马III标准的肠易激综合征青少年患者随机分为互联网CBT或对照组。主要结果是针对IBS的胃肠道症状评定量表(GSRS-IBS)总分。次要结果包括青少年和家长的相关生活质量,以及家长评分的胃肠道症状。 研究纳入了101名青少年IBS患者(13–17岁),失访率低(6%),基于混合效