J Rheumatol:12个月内减少步行速度个体24个月内患骨关节炎的风险研究

2017-06-05 xiangting MedSci原创

使用20米步行测试评估12个月内的速度变化可能有助于识别在随后的24个月内发展rKOA风险增加的个体。

这项研究为了评估12个月内步行速度的变化和24个月内发展成为影像学膝骨关节炎(rKOA)风险之间的关联。

研究人员从骨关节炎倡议中纳入没有rKOA的参与者。步行速度的改变通过20米步行评估来确定,使用12个月随访的步行速度减去基线速度,和/或24个月随访行走速度减去12个月的速度。偶发rKOA被定义为在24个月内(即12至36 mos或24和48 mos之间的发生率)Kellgren-Lawrence关节炎分级进展到≥2。期间自我报告的重大膝盖损伤、年龄、体重指数(BMI)和老年人体力活动量表(PASE)评分为了分析进行了调整。

在1460名参与者(58%女性,年龄59±9岁,范围45-79岁)中进行了2638次观察。12个月的步行速度平均变化为0.001±0.13m / s(范围-0.6271-1.4968)。大约5%的样本(n=122)在24个月内发展为rKOA。在控制重大膝盖损伤、年龄、BMI和PASE评分后,发现在12个月内步行速度每下降0.1米/秒,发展rKOA风险相对增加8%(风险比为1.08,95% CI 1.00-1.15,p=0.05)。

使用20米步行测试评估12个月内的速度变化可能有助于识别在随后的24个月内发展rKOA风险增加的个体。识别患rKOA风险高的个体可使医院实施早期干预措施,以促进关节健康。

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    2018-05-10 yuanming15
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    2017-11-20 lisa438
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    2017-06-07 lmm397

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