Stroke: 预测卒中后早期死亡的新量表:mSOAR

2015-11-24 MedSci MedSci原创

背景和目的:脑卒中类型,OCSP分类,年龄,及卒中前mRS分数是急性卒中后预测早期死亡的量表。研究者旨在评估最初卒中严重程度(NHISS和mSOAR)是否能改善预测的准确性。方法:使用Anglia卒中与心脏临床网络数据,研究者应用ROC曲线评估了2008年到2011年SOAR和mSOAR对住院死亡率的表现。研究者应用Glasgow独立队列数据评估应用SOAR和mSOAR对预后预测的外部效度。研究者

背景和目的:脑卒中类型,OCSP分类,年龄,及卒中前mRS分数是急性卒中后预测早期死亡的量表。研究者旨在评估最初卒中严重程度(NHISS和mSOAR)是否能改善预测的准确性。

方法:使用Anglia卒中与心脏临床网络数据,研究者应用ROC曲线评估了2008年到2011年SOAR和mSOAR对住院死亡率的表现。研究者应用Glasgow独立队列数据评估应用SOAR和mSOAR对预后预测的外部效度。研究者应用Hosmer-Lemeshow拟合优度描述标度。

结果:在这个队列试验中,共有1002名患者,105例(10.5%)死亡。SOAR和mSOAR评估早期死亡的的ROC曲线为0.79(95%CI ,0.75-0.84)和0.83(95%CI,0.79-0.86)。外部效度数据集中共有1012名卒中患者,其中,121例(12%)在90天内死亡。mSOAR分数识别早期死亡的概率从3%到42%。mSOAR分数外在效度验证早期死亡的ROC曲线面积0.84(95%CI:0
.82-0.88)。标度良好(Hosmer-Lemeshow检验P = 0.70)。

结论:增加NHISS分数重建一个新量表mSOAR分数改善预测预后的效度。临床上可能应用mSOAR预测死亡。

原文出处:

Abdul-Rahim AH, Quinn TJ, et al. Derivation and Validation of a Novel Prognostic Scale (Modified-Stroke Subtype, Oxfordshire Community Stroke Project Classification, Age, and Prestroke Modified Rankin) to Predict Early Mortality in Acute Stroke. Stroke. 2015 Nov 17.

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