Obesity:强化生活方式干预可获得长期减肥效果(look AHEAD研究评估)

2014-02-18 佚名 丁香园

来自美国宾夕法尼亚大学的Wadden教授及其团队,对Look AHEAD(Action for Health in Diabetes)研究中强化生活方式干预的减肥效果进行了评估,评估结果发表在近期的Obesity杂志上。【原文下载】 Look Ahead研究共纳入5145例超重/肥胖的成年2型糖尿病患者,随机分配到强化干预组和常规教育组,评估了减肥对心血管发病率和死亡

来自美国宾夕法尼亚大学的Wadden教授及其团队,对Look AHEAD(Action for Health in Diabetes)研究中强化生活方式干预的减肥效果进行了评估,评估结果发表在近期的Obesity杂志上。【原文下载】

Look Ahead研究共纳入5145例超重/肥胖的成年2型糖尿病患者,随机分配到强化干预组和常规教育组,评估了减肥对心血管发病率和死亡率的影响。强化干预组接受8年全方位的减肥咨询,包括饮食、锻炼,常规治疗组仅接受定期的健康教育。

试验中,超过88%的受试者完成了8年的结果评价。强化干预组和常规教育组的体重分别下降了4.7%和2.1%.其中,体重下降≥5%的受试者分别占50.3和35.7%,体重下降≥10%的分别占26.9%和17.2%.与常规教育组相比,强化干预组8年期间在体重控制的关键措施上实践更多,比如高强度的体育锻炼、减少卡路里的摄取量、频繁而规律的体重监测。此外,强化干预组体重下降≥10%的受试人群中,关键措施实施到位的患者体重保持较好,反弹人数较少。

通过8年强化生活方式干预,50%的2型糖尿病患者减肥效果显著(体重下降≥5%),建议该强化干预用于肥胖其他相关并发症的管理。

原始出处:

Look AHEAD Research Group.Eight-year weight losses with an intensive lifestyle intervention: The look AHEAD study.Obesity (Silver Spring). 2014 Jan;22(1):5-13. doi: 10.1002/oby.20662.【原文下载】

相关阅读:

Obesity:Look AHEAD研究,减肥者的新希望?

ADA 2013:2型糖尿病患者强化生活方式干预无心血管获益(Look AHEAD研究)

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    2014-07-28 智慧医人
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    2014-04-27 nymo
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    2014-04-16 117.136.8.100

    核心可能不是强化,而是持续!8年持续干预获益是惊人的,全方位的

    0

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    2014-02-20 lingaifan
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    2014-02-20 skhzy

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Obesity:Look AHEAD研究,减肥者的新希望?

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