FASEB:空气污染增加肥胖风险

2016-02-23 QQduhp 译 MedSci原创

研究人员进行了一项实验,他们将怀孕小鼠随机分为两组,一组暴露于北京户外空气,另一组小鼠所处环境中含有一个空气过滤器,可去除大部分的空气污染颗粒。研究人员饲喂3-8周后即出现变化。 仅19天后,暴露于北京户外空气的怀孕小鼠的肺和肝脏体积增大,且显示组织炎症的出现。相比暴露于含有空气过滤器的小鼠而言,暴露于北京户外的小鼠血液中低密度脂蛋白胆固醇增加50%、甘油三酯增加46%、总胆固醇增加97%。此外,

研究人员进行了一项实验,他们将怀孕小鼠随机分为两组,一组暴露于北京户外空气,另一组小鼠处于含有一个空气过滤器(可去除大部分的空气污染颗粒)的环境中。研究人员饲喂3-8周后即出现变化。 


仅19天后,暴露于北京户外空气的怀孕小鼠的肺和肝脏体积增大,且显示组织炎症的出现。相对于暴露于含有空气过滤器的小鼠而言,暴露于北京户外的小鼠血液中低密度脂蛋白胆固醇增加50%、甘油三酯增加46%、总胆固醇增加97%。此外,还出现了胰岛素抵抗,这是出现2型糖尿病的前兆。这项研究的结论是,民众处于空气污染的环境下会导致机体出现代谢障碍,这是民众出现肥胖的征兆。此外,在同样饮食的条件下,暴露于北京室外的小鼠明显较另一组小鼠肥胖。该组小鼠的后代出现了同样的表现。

然而,相比饲喂8周的小鼠,饲喂3周的小鼠面临的空气污染负面影响不太明显。长期暴露空气污染的条件下可导致小鼠出现炎症和代谢变化,最终导致体重的增加。相比暴露于清洁空气下8周的小鼠而言,暴露于污染空气条件下的雌性和雄性小鼠体重分别增加10%和18%。 

既往研究也指出空气污染会增加机体的胰岛素抵抗并改变脂肪组织。

慢性炎症被认为是导致肥胖和代谢性疾病的原因之一。研究结果充分表明,长期暴露在空气污染条件下会增加民众患肥胖症的风险。民众和政府需要行动起来,共同营造一片蓝色天空。

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    2016-06-17 gracezdd
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    2016-03-09 段段

    增加投入治理空气污染

    0

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    2016-03-05 1de48a27m96(暂无匿称)

    天哪。。

    0

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    2016-02-24 忠诚向上

    畏惧

    0

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