Stroke:急诊脑静脉血栓形成的误诊分析!

2018-04-25 xing.T MedSci原创

由此可见,在一个大型的、异质的多状态队列中,30例患者中有1例可能出现CVT误诊,但与不良临床结局无关。

急诊脑静脉血栓形成(CVT)误诊率以及与误诊相关的结局尚未明确。近日,卒中领域权威杂志Stroke上发表了一篇研究文章,研究人员利用行政数据,确定了纽约、加利福尼亚和佛罗里达州医院中2005年至2013年期间诊治的成年CVT患者。

该研究的主要结局为可能的CVT误诊。此外,研究人员使用Logistic回归比较了有无CVT误诊患者的临床转归率,并在2个三级护理中心进行了验证性研究。

该研究共确定了5966例CVT患者,其中216例(3.6%;95%可信区间[CI]为1.1%~4.1%)有可能的CVT误诊。在调整人口统计学、CVT的危险因素和Elixhauser合并症指数之后,可能的CVT误诊与住院死亡率(比值比为0.14、95%CI为0.02~1.05)、脑出血(比值比为0.97、95%CI为0.57~1.65)或不良出院结局无关(比值比为0.90;95%CI为0.61~1.32);CVT误诊患者的住院时间较长(比值比为1.62;95% CI为1.04~2.50)。在验证性队列中,134例CVT患者中有8例发生CVT误诊(6%;95%CI为2.6%~11.4%)。

由此可见,在一个大型的、异质的多状态队列中,30例患者中有1例可能出现CVT误诊,但与不良临床结局无关。

原始出处:


Ava L. Liberman,et al. Misdiagnosis of Cerebral Vein Thrombosis in the Emergency Department.Stroke. 2018. https://doi.org/10.1161/STROKEAHA.118.021058

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    2018-08-04 xue8602
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    2018-06-12 fusion
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    2018-04-25 张新亮1853311252142e2fm

    好文章.学习了

    0

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    2018-04-25 虈亣靌

    不错.学习了.做笔记了.谢谢分享!

    0

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