NEJM:肢端黑色素瘤案例报道

2015-11-05 陈说 译 MedSci原创

男性,58岁,左足跟部出现黑色斑块溃疡一年余未愈合而来院就诊。 体格检查可见,黑色斑块溃疡大小为6.5cm*5.5cm。切除活体组织检查,结果显示为肢端黑色素瘤,Breslow分级为深度2mm。左腹股沟淋巴结中的前哨淋巴结活检结果阴性。 在医生的建议下,患者同意行广泛性局部切除,切除范围达到溃疡边缘外2cm。 在术后的2年随访过程中,未见有复发的迹象。 肢端

男性,58岁,左足跟部出现黑色斑块溃疡一年余未愈合而来院就诊。


体格检查可见,黑色斑块溃疡大小为6.5cm*5.5cm。切除活体组织检查,结果显示为肢端黑色素瘤,Breslow分级为深度2mm。左腹股沟淋巴结中的前哨淋巴结活检结果阴性。


在医生的建议下,患者同意行广泛性局部切除,切除范围达到溃疡边缘外2cm。

在术后的2年随访过程中,未见有复发的迹象。

肢端黑色素瘤是一种罕见的变异黑色素瘤,通常发生在手掌和脚掌。它是黑色素瘤中最常见的黑色素瘤组织学类型之一。尽管非西班牙裔白人患者患黑色素瘤的发病率较高,但是,黑人患黑色素瘤(无论是组织学亚型)更容易发展为晚期,且生存率比白人更低。

在本案例中该患者的病情分级为晚期疾病,其原因目前尚未清楚,但很有可能是由于诊治延误导致的。

原始出处:

Mildred P. Warren,Valerie M. Harvey.Acral Lentiginous Melanoma.N Engl J Med 2015; 373:1864,November 5, 2015

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    2016-11-17 laoli

    典型病例!学习了!

    0

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    2016-04-09 sunylz
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