Lancet:死亡风险到底归因于极冷还是极热?

2015-05-26 范伟译 MedSci原创

背景:在选定的国家中,尽管研究提供过早死亡归因于热或冷,但到目前为止暴露于不同气候的人群整个温度范围内没有提供系统的评估。我们旨在量化总死亡率的负担,归因于非最适宜的环境温度,来自冷和热,适中的和极端的温度的相对影响。方法:我们收集的数据来自澳大利亚、巴西、加拿大、中国、意大利、日本、韩国、西班牙、瑞典、台湾、泰国、英国和美国的384个地点。我们为每个地点设置一个时间序列泊松回归模型,控制每周的趋

背景:在选定的国家中,尽管研究提供过早死亡归因于热或冷,但到目前为止暴露于不同气候的人群整个温度范围内没有提供系统的评估。我们旨在量化总死亡率的负担,归因于非最适宜的环境温度,来自冷和热,适中的和极端的温度的相对影响。

方法:我们收集的数据来自澳大利亚、巴西、加拿大、中国、意大利、日本、韩国、西班牙、瑞典、台湾、泰国、英国和美国的384个地点。我们为每个地点设置一个时间序列泊松回归模型,控制每周的趋势和天数。我们估测温度-死亡率的关联,采用21天延迟的分布滞后的非线性模型,然后把他们汇集在多元meta回归分析中包括国家指标,平均温度和范围。我们计算冷和热的归因死亡,定义之上和之下的最适宜温度,其与最低死亡率相一致,对于中等的和极端的温度,使用2.5th和97.5th温度百分位数截止。 



结果:在1985年和2012年之间各个时期,我们分析了74 225200名死亡的人。在选定国家的研究期间内,总共7.71%(95% 实证的CI 7.43-7.91)的死亡率可归因于非最适宜的温度,国家之间有着显著的差异,从泰国的3.37%(3.06 - 3.63)到中国的 11.00%(9.29 - 12.47)。最低死亡率温度的百分比从热带地区大约60th百分位数变化到温带地区大约80 -90th百分位数。更多的归因温度的死亡是由于冷(7.29%,7.02-7.49)而不是由于热(0.42%,0.39-0.44)。极端的冷热气温造成了0.86%(0.84 - 0.87)的总死亡率。

结论:大部分跟温度有关的死亡率过重可归因于寒冷的原因。极端温度的影响实质上低于中等的天气但非最适宜的天气。这个证据对公共卫生干预措施的规划具有重要影响,将不良温度的健康影响降到最低,在气候变化情况下预测未来的可能影响后果。 


原始出处:

Gasparrini A1, Guo Y2, Hashizume M3, Lavigne E4, Zanobetti A5, Schwartz J5,
Tobias A6, Tong S7, Rocklöv J8, Forsberg B8, Leone M9, De Sario M9, Bell ML10,
Guo YL11, Wu CF12, Kan H13, Yi SM14, de Sousa Zanotti Stagliorio Coelh M15,
Saldiva PH15, Honda Y16, Kim H14, Armstrong B17.Mortality risk attributable to
high and low ambient temperature: a multicountry observational study
.
Lancet. 2015 May 19. pii: S0140-6736(14)62114-0.
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    2016-03-02 howi
  2. [GetPortalCommentsPageByObjectIdResponse(id=1828119, encodeId=26b91828119a5, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Wed Mar 02 00:03:00 CST 2016, time=2016-03-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=28825, encodeId=8dd52882538, content=都不好, beContent=null, objectType=article, channel=null, level=null, likeNumber=119, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ded71629504, createdName=nizongzan, createdTime=Thu Jun 25 09:44:00 CST 2015, time=2015-06-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=25628, encodeId=d4bd25628ed, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=162, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Sun May 31 21:34:00 CST 2015, time=2015-05-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=25414, encodeId=a36b2541439, content=这个研究厉害, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=9e0b1603164, createdName=lovejing, createdTime=Sat May 30 15:55:00 CST 2015, time=2015-05-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1255516, encodeId=1ca41255516a3, content=<a href='/topic/show?id=587f6339050' target=_blank style='color:#2F92EE;'>#死亡风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63390, encryptionId=587f6339050, topicName=死亡风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Thu May 28 12:03:00 CST 2015, time=2015-05-28, status=1, ipAttribution=)]
    2015-06-25 nizongzan

    都不好

    0

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    2015-05-31 huaxipanxing

    看看

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1828119, encodeId=26b91828119a5, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Wed Mar 02 00:03:00 CST 2016, time=2016-03-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=28825, encodeId=8dd52882538, content=都不好, beContent=null, objectType=article, channel=null, level=null, likeNumber=119, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ded71629504, createdName=nizongzan, createdTime=Thu Jun 25 09:44:00 CST 2015, time=2015-06-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=25628, encodeId=d4bd25628ed, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=162, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Sun May 31 21:34:00 CST 2015, time=2015-05-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=25414, encodeId=a36b2541439, content=这个研究厉害, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=9e0b1603164, createdName=lovejing, createdTime=Sat May 30 15:55:00 CST 2015, time=2015-05-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1255516, encodeId=1ca41255516a3, content=<a href='/topic/show?id=587f6339050' target=_blank style='color:#2F92EE;'>#死亡风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63390, encryptionId=587f6339050, topicName=死亡风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Thu May 28 12:03:00 CST 2015, time=2015-05-28, status=1, ipAttribution=)]
    2015-05-30 lovejing

    这个研究厉害

    0

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