Clinica Chimica Acta:健康献血者单核细胞分布宽度(MDW)的参考区间?

2020-08-09 MedSci原创 MedSci原创

本研究的目的是利用不同的统计方法,用直接法准确地建立健康献血者单核细胞分布宽度的参考区间(RI)。

本研究的目的是利用不同的统计方法,用直接法准确地建立健康献血者单核细胞分布宽度的参考区间(RI)。

486名受试者的MDW进行了测量。MDW的RI通过非参数法、鲁棒法和Harrell-Davis bootstrap方法计算,并使用不同的检验来识别潜在的异常值(Dixon-Reed和Tukey)。

采用非参数法计算的RI的上、下参考限分别为:16.22 (90%CI 15.78-16.47) - 23.15 (90%CI 22.80-24.10)(不去除离群值),16.44 (90%CI 16.21-16.67) - 22.99 (90%CI 22.33-23.22)(去除离群值后)。基于稳健方法的RIs值分别为16.29-22.98(不含)和16.50-22.67(含离群值去除)。最后,采用Harrell-Davis bootstrap方法计算的RIs,无论是否去除离群值,分别为16.19-23.24和16.43-22.93。因此,三种计算方法得到的RIs非常相似。此外,由于没有发现显著的性别或年龄相关性,因此没有进行RI分区。

研究结果支持使用一种独立于性别和年龄的独特的MDW RI。

原始出处:

LuisaAgnello,Bruna Lo Sasso,Reference interval of monocyte distribution width (MDW) in healthy blood donors

 

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (3)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1850015, encodeId=a95f18500156b, content=<a href='/topic/show?id=61815385aa' target=_blank style='color:#2F92EE;'>#CTA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5385, encryptionId=61815385aa, topicName=CTA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ec9955, createdName=windight, createdTime=Mon Feb 15 14:58:03 CST 2021, time=2021-02-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1299145, encodeId=406c129914590, content=<a href='/topic/show?id=2b85362063c' target=_blank style='color:#2F92EE;'>#单核细胞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36206, encryptionId=2b85362063c, topicName=单核细胞)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=daa8281, createdName=雕雕, createdTime=Tue Aug 11 13:58:03 CST 2020, time=2020-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1546923, encodeId=93991546923ac, content=<a href='/topic/show?id=ed723e350e0' target=_blank style='color:#2F92EE;'>#参考区间#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37350, encryptionId=ed723e350e0, topicName=参考区间)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=910c13959987, createdName=12498dabm81暂无昵称, createdTime=Tue Aug 11 13:58:03 CST 2020, time=2020-08-11, status=1, ipAttribution=)]
    2021-02-15 windight
  2. [GetPortalCommentsPageByObjectIdResponse(id=1850015, encodeId=a95f18500156b, content=<a href='/topic/show?id=61815385aa' target=_blank style='color:#2F92EE;'>#CTA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5385, encryptionId=61815385aa, topicName=CTA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ec9955, createdName=windight, createdTime=Mon Feb 15 14:58:03 CST 2021, time=2021-02-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1299145, encodeId=406c129914590, content=<a href='/topic/show?id=2b85362063c' target=_blank style='color:#2F92EE;'>#单核细胞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36206, encryptionId=2b85362063c, topicName=单核细胞)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=daa8281, createdName=雕雕, createdTime=Tue Aug 11 13:58:03 CST 2020, time=2020-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1546923, encodeId=93991546923ac, content=<a href='/topic/show?id=ed723e350e0' target=_blank style='color:#2F92EE;'>#参考区间#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37350, encryptionId=ed723e350e0, topicName=参考区间)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=910c13959987, createdName=12498dabm81暂无昵称, createdTime=Tue Aug 11 13:58:03 CST 2020, time=2020-08-11, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1850015, encodeId=a95f18500156b, content=<a href='/topic/show?id=61815385aa' target=_blank style='color:#2F92EE;'>#CTA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5385, encryptionId=61815385aa, topicName=CTA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ec9955, createdName=windight, createdTime=Mon Feb 15 14:58:03 CST 2021, time=2021-02-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1299145, encodeId=406c129914590, content=<a href='/topic/show?id=2b85362063c' target=_blank style='color:#2F92EE;'>#单核细胞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36206, encryptionId=2b85362063c, topicName=单核细胞)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=daa8281, createdName=雕雕, createdTime=Tue Aug 11 13:58:03 CST 2020, time=2020-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1546923, encodeId=93991546923ac, content=<a href='/topic/show?id=ed723e350e0' target=_blank style='color:#2F92EE;'>#参考区间#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37350, encryptionId=ed723e350e0, topicName=参考区间)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=910c13959987, createdName=12498dabm81暂无昵称, createdTime=Tue Aug 11 13:58:03 CST 2020, time=2020-08-11, status=1, ipAttribution=)]

相关资讯

仅3.57%的临床实验室自己确定甲功参考区间

《检验医学》杂志2016年第4期刊登了费阳, 王薇, 王治国的“490家临床实验室甲状腺功能5项参考区间现况调查”。 本研究调查的490家实验室分布于全国29个地区, 多为三级医院, 且参加了卫生部临床检验中心室间质量评价, 可以反映我国性能较好的临床实验室甲状腺功能5项参考区间的现状。 国际临床化学联合会(the International Federation of Clinica