Human Brain Mapping：长期吸食大麻改变大脑奖赏回路

2016-06-13 佚名生物谷

根据达拉斯得克萨斯大学的大脑健康中心研究人员称，长期吸食大麻会破坏大脑的自然奖励过程。一篇发表在《Human Brain Mapping》杂志上的文章称，研究人员首次演示了功能性磁共振成像技术，研究表明长期吸食大麻会造成大脑皮层奖励系统中产生更多的活动。 “这项研究表明，大麻会扰乱大脑的自然反馈回路，尤其是大量吸食大麻的人问题更严重。从本质上说，这些大脑改变可能是由于轻度吸食大麻到重度吸食

根据达拉斯得克萨斯大学的大脑健康中心研究人员称，长期吸食大麻会破坏大脑的自然奖励过程。

一篇发表在《Human Brain Mapping》杂志上的文章称，研究人员首次演示了功能性磁共振成像技术，研究表明长期吸食大麻会造成大脑皮层奖励系统中产生更多的活动。

“这项研究表明，大麻会扰乱大脑的自然反馈回路，尤其是大量吸食大麻的人问题更严重。从本质上说，这些大脑改变可能是由于轻度吸食大麻到重度吸食大麻引起的。”Francesca Filbey博士说，他是大脑健康中心成瘾障碍认知神经科学研究中心主任，行为与大脑科学学校的副教授。

在这项研究中，研究人员分析了59名成年大麻吸食者和70名非大麻吸食者，这些吸毒者创伤性脑损伤和吸食其他毒品之间存在潜在性偏倚。研究参与者认为大麻吸食者在受了各种视觉刺激如烟斗、大麻烟斗后就想吸食大麻。

研究人员还从研究参与者中收集了自我报告用来测试吸食大麻有关的问题。平均来说，参与者大麻吸食时间约12年。大麻吸食者的奖赏相关的大脑区域如眼窝前额皮质、纹状体、前扣带皮层楔前叶和腹侧被盖区显示增强反应。

“我们发现了与大脑奖励系统中断相关的许多问题，比如个体因为吸食大麻产生的家庭问题。”Filbey说。

原始出处

Francesca M. Filbey*, Joseph Dunlop, Ariel Ketcherside, Jessica Baine, Tyler Rhinehardt, Brittany Kuhn, Sam DeWitt andTalha Alvi.fMRI study of neural sensitization to hedonic stimuli in long-term, daily cannabis users.Human Brain Mapping.2016

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#插入话题

插入图片

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2017-01-15 ms7421025882867189

#mapping#

43 0
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2017-01-28 wmu姿

好文章学习了

56 0
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2017-05-10 heli0118

#human#

37 0
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2016-07-02 hanhaisha2008

#吸食大麻#

34 0
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2016-10-12 ylzr123

拜读了，受益匪浅，点个赞！

63 0
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2016-06-15 kcb069

#大麻#

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