Ocul Surf:高分辨率光学相干断层扫描在眼表鳞状上皮细胞瘤合并眼表疾病诊断中的作用

2017-04-25 luowenbo MedSci原创

眼表疾病可能会掩盖眼表鳞状上皮细胞瘤(OSSN)的典型特征,本研究目的在于评估高分辨率光学相干断层扫描(HR-OCT)作为辅助手段在检测与眼表疾病共存的OSSN中的作用。

高分辨率光学相干断层扫描在眼表鳞状上皮细胞瘤合并眼表疾病诊断中的作用

眼表疾病可能会掩盖眼表鳞状上皮细胞瘤(OSSN)的典型特征,本研究目的在于评估高分辨率光学相干断层扫描(HR-OCT)作为辅助手段在检测与眼表疾病共存的OSSN中的作用。

对16例具有眼表疾病并存可疑OSSN的眼表肿物的患者进行回顾性研究。对16例患者进行HR-OCT检测,HR-OCT显像用来作为寻找OSSN的证据,同时所有病例都进行活检,将HR-OCT图像结果与活检结果进行对比。

结果发现,在16例眼表肿物可疑为OSSN与眼表疾病共存的患者中,12例患者通过HR-OCT检查诊断OSSN,该结果随后得到活检结果的验证。所有12例HR-OCT显像都显示上皮层高反射性增厚以及上皮细胞的异常突变。4例患者通过HR-OCT检查后排除OSSN,随后活检结果确诊为OSSN阴性。HR-OCT还用于OSSN阳性患者治疗后的随访检查,并发现一例复发。

虽然组织病理学检查是OSSN诊断的金标准,HR-OCT也作为合并眼表疾病的患者的OSSN检测的非侵入性检测方法。

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    2017-12-26 lsndxfj
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