J Craniofac Surg: 淋巴球中性粒细胞和血小板比例对慢性中耳炎积液粘度的预测值

2017-05-13 AlexYang MedSci原创

最近,研究人员就淋巴球中性粒细胞(NLR)和淋巴球血小板(PLR)在中耳炎积液中的预测值进行了研究,并同时探索了积液类型与这些比例的关系。该研究设计为设置对照的回顾性案例研究。该研究包括了126名诊断为慢性中耳炎积液且有插入疏通管的儿科病人为研究群体,时间为2015年10月到2016年7月。研究的对照组为124名健康的儿童,研究人员对对照组进行了例行检查和血细胞计数分析。研究人员从病人的手术记录中

最近,研究人员就淋巴球中性粒细胞(NLR)和淋巴球血小板(PLR)在中耳炎积液中的预测值进行了研究,并同时探索了积液类型与这些比例的关系。该研究设计为设置对照的回顾性案例研究。

该研究包括了126名诊断为慢性中耳炎积液且有插入疏通管的儿科病人为研究群体,时间为2015年10月到2016年7月。研究的对照组为124名健康的儿童,研究人员对对照组进行了例行检查和血细胞计数分析。研究人员从病人的手术记录中根据病人的积液类型将研究组分成了两个小组。其中,71名病人分在了浆液性小组,55名病人分到了黏液性小组。并且对小组的NLR和PLR比例进行的比较和统计学评估。

研究发现,在研究小组中,平均的NLR和PLE比例要比对照组显著的高(分别为P=0.000, P=0.004)。浆液小组和黏液小组与对照组比较表明了对照组与浆液小组在NLR和PLR中有着显著的差异(分别为P=0.000,P=0.000),但是在对照组和黏液小组中没有差异(分别为P=0.694; P=0.691)。最后,研究人员指出,淋巴球中性粒细胞的比例和淋巴球血小板在中耳炎积液中有着预测价值,另外,该研究是实验室数据,支持了中耳积累液体的积液分型。

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    2017-05-17 laoli

    学习了,谢谢分享!

    0

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    2017-05-13 明月清辉

    谢谢分享,学习了

    0

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急性中耳炎是中耳的一种快速感染,并能够导致中耳压力和中耳积液,以及中耳组织的结构改变。以前的研究表明,MEP、MEE和中耳结构改变是影响鼓膜(TM)移动性和听力水平的三个因素。声能反射比或者吸收率(EA)在临床中耳疾病鉴定中越来越多的被应用作为一种诊断工具。然而,是否EA可以在AOM耳朵中区别这三个因素还不清楚。最近,研究人员报道了在仓鼠APM模型中的宽带频EA测量,实验分为三个阶段:未开放、压力

Comput Methods Biomech Biomed Engin:人类分泌性中耳炎研究

中耳炎是一种中耳的炎症性疾病。急性中耳炎和分泌性中耳炎(OME)是中耳炎的两种主要表现类型。中耳炎在儿童中非常普遍,并且可以导致中耳结构的改变最终引起听力损失。最近,有研究人员就从外耳道到内耳过程中,OME对声音传输的影响进行了研究。在生物力学研究中,研究人员利用了有限元方法。并且,在该研究中,数值模型是基于从视觉耳朵工程获得的几何资料建立起来的。通过评估计算量级、时期和正常鼓膜速度的减少,研究揭

Iran J Otorhinolaryngol:儿童中耳炎积液和血清细胞激素水平风险因子的影响

最近,有研究人员就患有慢性中耳炎积液(OME)儿童中的过敏性类型和传染类型细胞激素进行了评估。研究人员将患有中耳炎积液的35名儿童和28名健康儿童作为研究群体,并利用酶联免疫实验(ELISA)调查了白介素-4、白介素-5和白介素-13的血清水平,以及干扰素伽马(IFN-γ)和肿瘤坏死因子阿尔法(TNF-α)在血清中的水平。研究发现,和对照组相比,患有中耳炎积液的儿童具有显著的更高的白介素-5水平,

Laryngoscope:正常中耳和慢性中耳炎的微生物

最近,有研究人员就人类正常中耳和慢性中耳炎的微生物进行了分析和比较,研究设计为前瞻性多中心群体研究。研究招募了连续性发病病人并经历了慢性中耳炎中耳整复术或者手术,不包括中耳炎患者。无菌抽汲样品在外科手术中从中耳黏膜中收集。研究人员对每个样品中的16S rRNA 基因可变区域4进行了特异性引物扩增,并利用Illumina MiSeq测序仪进行测序分析。序列结果利用局部比对分析,并利用Metageno

J Craniofac Surg: 中耳炎积液鼓膜压力梯度值范围

最近,有研究人员就鼓室导抗图在预测中耳炎积液的表现或缺陷的可靠度进行了研究,并且为鼓室导抗测试的诊断信息提供了新的观点。研究关注于鼓膜压力梯度而不是静态导纳的应用。研究人员召集了146名女性和129名男性患者。研究人员将参与者分配成不同的小组:A1组包括50名健康的儿童;A2组包括86名患有中耳炎积液的儿童;B1组包括85名健康成年人;B2组包括54名患有中耳炎积液的成年人。研究者对参与者的双耳进