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NEJM：血压控制——强化降压治疗vs标准降压治疗

2017-08-24 zhangfan MedSci原创

高血压心血管疾病风险
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对于高血压和心血管疾病风险增加的非糖尿病患者，强化降压治疗与标准降压治疗对患者临床结果差异不显著，患者的血压控制、生理或认知功能均保持稳定

先前的研究表明，对于高血压和心血管疾病风险增加的非糖尿病受试者，强化降压治疗(收缩压<120mmHg)相比于常规降压治疗(收缩压<140mmHg)可显著降低患者的心血管事件发生率，近日研究人员公布了该研究的最终患者临床结果。研究招募了9361名患者，随机接受强化降压治疗或常规降压治疗。患者临床终点评分方法包括身体机能评分(PCS)、心理机能评分(MCS)、患者抑郁状态评分(PHQ-9)、血压控制和降压药物依从性满意度。强化治疗组患者平均服用1种抗高血压药物，收缩压较标准治疗组低14.8mmHg(95% CI，14.3-15.4)。PCS, MCS以及PHQ-9平均分数在3年的随访中保持稳定，组间无显著差异。组间生理或认知功能分数无显著差异。两组血压控制的满意度较高，降压药物的患者依从性无显著差异。研究发现，对于高血压和心血管疾病风险增加的非糖尿病患者，强化降压治疗与标准降压治疗对患者临床结果差异不显著，患者的血压控制、生理或认知功能均保持稳定。原始出处：Dan R. Berlowitz et al. Effect of Intensive Blood-Pressure Tr

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    2017-08-26 经常头晕

    #降压#

    0

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    2017-08-26 xugumin

    #降压治疗#

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1291923, encodeId=ce0912919232b, content=<a href='/topic/show?id=9d32981418b' target=_blank style='color:#2F92EE;'>#降压#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98141, encryptionId=9d32981418b, topicName=降压)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8f14236, createdName=经常头晕, createdTime=Sat Aug 26 10:35:00 CST 2017, time=2017-08-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1360866, encodeId=facc1360866ab, content=<a href='/topic/show?id=87fe98146d7' target=_blank style='color:#2F92EE;'>#降压治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98146, encryptionId=87fe98146d7, topicName=降压治疗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=xugumin, createdTime=Sat Aug 26 10:35:00 CST 2017, time=2017-08-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1419078, encodeId=8eb714190e8b8, content=<a href='/topic/show?id=e051501461d' target=_blank style='color:#2F92EE;'>#强化降压#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50146, encryptionId=e051501461d, topicName=强化降压)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2c6c3470765, createdName=fengxx, createdTime=Sat Aug 26 10:35:00 CST 2017, time=2017-08-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1446289, encodeId=b8e7144628987, content=<a href='/topic/show?id=875e88946d1' target=_blank style='color:#2F92EE;'>#血压控制#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=88946, encryptionId=875e88946d1, topicName=血压控制)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=28a45200046, createdName=gj0733, createdTime=Sat Aug 26 10:35:00 CST 2017, time=2017-08-26, status=1, ipAttribution=)]
    2017-08-26 fengxx

    #强化降压#

    0

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    2017-08-26 gj0733

    #血压控制#

    0

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