Hypertension:尿路结石冲击波碎石术会增加新发高血压的风险!

2017-08-22 xing.T MedSci原创

因此,改变尿石症的治疗方案(如内镜手术或药物排石疗法)可以避免高血压的风险。此外,避免多个疗程的冲击波碎石术也可以规避高血压风险。

虽然冲击波碎石术是微创的,早期的研究认为它可能会增加患者的高血压糖尿病的风险。近日,心血管权威杂志Hypertension上发表了一篇研究文章,该研究旨在评估冲击波碎石术和新发高血压糖尿病之间的相关性。

研究人员通过台湾全民健康保险研究数据库确定了1999年1月和2011年12月期间年龄在18岁至65岁之间的20219例接受首次结石外科治疗(冲击波碎石术、输尿管镜气压弹道碎石术)的患者。Cox比例模型被用于评估它们之间的相关性。时间变化的Cox模型被用来评估冲击波碎石术的次数与高血压或糖尿病发生率之间的关系。

在中位随访74.9个月和82.6个月后,分别有2028例和688例患者接受了冲击波碎石术与输尿管镜碎石术的患者发生了高血压。在调整协变量后,研究人员发现行体外冲击波碎石术的患者发生高血压的可能性要比行输尿管镜气压弹道碎石术患者要高,其风险比为1.20(95%可信区间为1.10-1.31)。冲击波碎石次数增加,患者高血压的风险也有所增加。然而,发生糖尿病风险在接受冲击波碎石术治疗与输尿管镜碎石术治疗的患者相似。此外,其风险比并不随着冲击波碎石次数增加而增加。在长期随访中,研究人员发现冲击波碎石会不断增加高血压的发病率。

因此,改变尿石症的治疗方案(如内镜手术或药物排石疗法)可以避免高血压的风险。此外,避免多个疗程的冲击波碎石术也可以规避高血压风险。

原始出处:

Shi-Wei Huang,et al. Increased Risk of New-Onset Hypertension After Shock Wave Lithotripsy in Urolithiasis A Nationwide Cohort Study.Hypertension.2017. https://doi.org/10.1161/HYPERTENSIONAHA.117.09669

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content=改变尿石症的治疗方案(如内镜手术或药物排石疗法)可以避免高血压的风险.此外.避免多个疗程的冲击波碎石术也可以规避高血压风险., beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Tue Aug 22 16:08:28 CST 2017, time=2017-08-22, status=1, ipAttribution=)]
    2018-01-04 feather89
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content=改变尿石症的治疗方案(如内镜手术或药物排石疗法)可以避免高血压的风险.此外.避免多个疗程的冲击波碎石术也可以规避高血压风险., beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Tue Aug 22 16:08:28 CST 2017, time=2017-08-22, status=1, ipAttribution=)]
    2017-09-07 哈哈869

    0

  4. 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createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKcmgibQ4oCrK7Z6f4CvMcs4k7QUGCkhopcGxvxaBfVciadECSIwaRVttllIOEKumpEaRrq5PoOUxow/0, createdBy=e3bb2081203, createdName=哈哈869, createdTime=Sat Sep 02 06:54:54 CST 2017, time=2017-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=237430, encodeId=95f523e4300e, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKcmgibQ4oCrK7Z6f4CvMcs4k7QUGCkhopcGxvxaBfVciadECSIwaRVttllIOEKumpEaRrq5PoOUxow/0, createdBy=e3bb2081203, createdName=哈哈869, createdTime=Sat Aug 26 19:20:30 CST 2017, time=2017-08-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=237429, encodeId=4f9b23e429b0, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKcmgibQ4oCrK7Z6f4CvMcs4k7QUGCkhopcGxvxaBfVciadECSIwaRVttllIOEKumpEaRrq5PoOUxow/0, createdBy=e3bb2081203, createdName=哈哈869, createdTime=Sat Aug 26 19:20:26 CST 2017, time=2017-08-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1501196, encodeId=c9aa150119689, content=<a href='/topic/show?id=f2db9238f9' target=_blank style='color:#2F92EE;'>#Hypertension#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9238, encryptionId=f2db9238f9, topicName=Hypertension)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=11ff9497046, createdName=jambiya, createdTime=Thu Aug 24 03:06:00 CST 2017, time=2017-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=236103, encodeId=750723610377, content=为什么呢?, beContent=null, objectType=article, channel=null, level=null, likeNumber=1, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5e291719269, createdName=大旺旺, createdTime=Tue Aug 22 20:38:01 CST 2017, time=2017-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=236087, encodeId=adaa23608eb5, content=学习了.谢谢., beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Tue Aug 22 18:31:40 CST 2017, time=2017-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=236042, encodeId=17f62360422e, content=改变尿石症的治疗方案(如内镜手术或药物排石疗法)可以避免高血压的风险.此外.避免多个疗程的冲击波碎石术也可以规避高血压风险., beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Tue Aug 22 16:08:28 CST 2017, time=2017-08-22, status=1, ipAttribution=)]
    2017-09-02 哈哈869

    玉佛

    0

  5. 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content=改变尿石症的治疗方案(如内镜手术或药物排石疗法)可以避免高血压的风险.此外.避免多个疗程的冲击波碎石术也可以规避高血压风险., beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Tue Aug 22 16:08:28 CST 2017, time=2017-08-22, status=1, ipAttribution=)]
    2017-08-26 哈哈869

    学习

    0

  6. 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beContent=null, objectType=article, channel=null, level=null, likeNumber=1, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5e291719269, createdName=大旺旺, createdTime=Tue Aug 22 20:38:01 CST 2017, time=2017-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=236087, encodeId=adaa23608eb5, content=学习了.谢谢., beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Tue Aug 22 18:31:40 CST 2017, time=2017-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=236042, encodeId=17f62360422e, content=改变尿石症的治疗方案(如内镜手术或药物排石疗法)可以避免高血压的风险.此外.避免多个疗程的冲击波碎石术也可以规避高血压风险., beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Tue Aug 22 16:08:28 CST 2017, time=2017-08-22, status=1, ipAttribution=)]
    2017-08-26 哈哈869

    学习

    0

  7. 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  8. 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content=改变尿石症的治疗方案(如内镜手术或药物排石疗法)可以避免高血压的风险.此外.避免多个疗程的冲击波碎石术也可以规避高血压风险., beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Tue Aug 22 16:08:28 CST 2017, time=2017-08-22, status=1, ipAttribution=)]
    2017-08-22 大旺旺

    为什么呢?

    0

  9. 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content=改变尿石症的治疗方案(如内镜手术或药物排石疗法)可以避免高血压的风险.此外.避免多个疗程的冲击波碎石术也可以规避高血压风险., beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Tue Aug 22 16:08:28 CST 2017, time=2017-08-22, status=1, ipAttribution=)]
    2017-08-22 惠映实验室

    学习了.谢谢.

    0

  10. 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content=改变尿石症的治疗方案(如内镜手术或药物排石疗法)可以避免高血压的风险.此外.避免多个疗程的冲击波碎石术也可以规避高血压风险., beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Tue Aug 22 16:08:28 CST 2017, time=2017-08-22, status=1, ipAttribution=)]
    2017-08-22 有备才能无患

    改变尿石症的治疗方案(如内镜手术或药物排石疗法)可以避免高血压的风险.此外.避免多个疗程的冲击波碎石术也可以规避高血压风险.

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