Am J Med:急性心肌梗死后高钾血症患病率和预后意义研究

2016-08-06 Mechront 译 MedSci原创

目的:高钾血症是住院患者常见的潜在危险;目前急性心肌梗死后的高钾血症患病率和预后意义仍不清楚。方法:对38689例急性心肌梗死患者进行了研究,评估最大住院血钾水平和住院患者死亡率之间的关系。根据透析状态和最大住院血钾水平对患者进行分层:<5 mEq/L、5~<5.5 mEq/L、5.5~<6.0 mEq/L、6.0~ <6.5 mEq/L和≥6.5 mEq/L。结果:386

目的:高钾血症是住院患者常见的潜在危险;目前急性心肌梗死后的高钾血症患病率和预后意义仍不清楚。

方法:对38689例急性心肌梗死患者进行了研究,评估最大住院血钾水平和住院患者死亡率之间的关系。根据透析状态和最大住院血钾水平对患者进行分层:<5 mEq/L、5~<5.5 mEq/L、5.5~<6.0 mEq/L、6.0~ <6.5 mEq/L和≥6.5 mEq/L。

结果:38689例急性心肌梗死患者中有886例透析。透析患者中,高钾血症率(最高血钾水平≥5.0 mEq/L)为22.6%;非透析患者中,该值为66.8%。9.8%的患者发生了中度至重度高钾血症(最高血钾水平≥5.5 mEq/L)。

更高的最大血钾水平与死亡率急剧增加有关。无论透析与否,当最大血钾≥5.5 mEq/L,住院死亡率超过15%;多变量调整后,联系仍存在。此外,患者经历的高钾血症次数越多,院内死亡率越高。

结论:高钾血症在急性心肌梗死患者中很常见。更高的最大血钾水平、更多的高钾血症次数与死亡率急剧增加相关,即使是轻度高钾血症,不良预后的风险也更高。对高钾血症进行更密集的管理能否提高急性心肌梗死患者的疗效有待进一步研究。

原始出处:


Grodzinsky A.et al.Prevalence and Prognosis of Hyperkalemia in Patients with Acute Myocardial Infarction.Am J Med. 2016 Aug;129(8):858-65. doi: 10.1016/j.amjmed.2016.03.008

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    2016-09-20 1e10c84am36(暂无匿称)

    文章很好,非常有益

    0

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    2016-09-12 舒心和人

    都是一下新文献中的知识,感谢分享

    0

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  7. [GetPortalCommentsPageByObjectIdResponse(id=131725, encodeId=5ca5131e251e, content=文章很好,非常有益, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Tue Sep 20 22:22:00 CST 2016, time=2016-09-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=124072, encodeId=79321240e2d3, content=都是一下新文献中的知识,感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160907/IMG57D00CF1965701770.jpg, createdBy=565c1948251, createdName=舒心和人, createdTime=Mon Sep 12 23:28:00 CST 2016, time=2016-09-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1250437, encodeId=3c99125043ea6, content=<a href='/topic/show?id=7d6f52988e1' target=_blank style='color:#2F92EE;'>#患病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52988, encryptionId=7d6f52988e1, topicName=患病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f49517, createdName=xinmeili, createdTime=Mon Aug 08 03:04:00 CST 2016, time=2016-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1514515, encodeId=8d2d151451517, content=<a href='/topic/show?id=102f102e8375' target=_blank style='color:#2F92EE;'>#高钾#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102783, encryptionId=102f102e8375, topicName=高钾)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=医者仁心, createdTime=Mon Aug 08 03:04:00 CST 2016, time=2016-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1546223, encodeId=a12d15462235a, content=<a href='/topic/show?id=a6fa100185d7' target=_blank style='color:#2F92EE;'>#预后意义#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100185, encryptionId=a6fa100185d7, topicName=预后意义)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=395f25, createdName=爆笑小医, createdTime=Mon Aug 08 03:04:00 CST 2016, time=2016-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1607022, encodeId=224c160e02213, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Mon Aug 08 03:04:00 CST 2016, time=2016-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=96771, encodeId=504496e7159, content=科学问题认真领会, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Sun Aug 07 17:56:00 CST 2016, time=2016-08-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=96421, encodeId=52aa96421c0, content=高钾血症!, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b09f1636586, createdName=onetree, createdTime=Sat Aug 06 12:33:00 CST 2016, time=2016-08-06, status=1, ipAttribution=)]
    2016-08-07 jyzxjiangqin

    科学问题认真领会

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=131725, encodeId=5ca5131e251e, content=文章很好,非常有益, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Tue Sep 20 22:22:00 CST 2016, time=2016-09-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=124072, encodeId=79321240e2d3, content=都是一下新文献中的知识,感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160907/IMG57D00CF1965701770.jpg, createdBy=565c1948251, createdName=舒心和人, createdTime=Mon Sep 12 23:28:00 CST 2016, time=2016-09-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1250437, encodeId=3c99125043ea6, content=<a href='/topic/show?id=7d6f52988e1' target=_blank style='color:#2F92EE;'>#患病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52988, encryptionId=7d6f52988e1, topicName=患病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f49517, createdName=xinmeili, createdTime=Mon Aug 08 03:04:00 CST 2016, time=2016-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1514515, encodeId=8d2d151451517, content=<a href='/topic/show?id=102f102e8375' target=_blank style='color:#2F92EE;'>#高钾#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102783, encryptionId=102f102e8375, topicName=高钾)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=医者仁心, createdTime=Mon Aug 08 03:04:00 CST 2016, time=2016-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1546223, encodeId=a12d15462235a, content=<a href='/topic/show?id=a6fa100185d7' target=_blank style='color:#2F92EE;'>#预后意义#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100185, encryptionId=a6fa100185d7, topicName=预后意义)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=395f25, createdName=爆笑小医, createdTime=Mon Aug 08 03:04:00 CST 2016, time=2016-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1607022, encodeId=224c160e02213, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Mon Aug 08 03:04:00 CST 2016, time=2016-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=96771, encodeId=504496e7159, content=科学问题认真领会, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Sun Aug 07 17:56:00 CST 2016, time=2016-08-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=96421, encodeId=52aa96421c0, content=高钾血症!, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b09f1636586, createdName=onetree, createdTime=Sat Aug 06 12:33:00 CST 2016, time=2016-08-06, status=1, ipAttribution=)]
    2016-08-06 onetree

    高钾血症!

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