Am J Med:吸烟会增加坐骨神经痛风险

2016-01-14 Seven L MedSci原创

当前关于吸烟对坐骨神经痛的影响仍不明确,研究者检索了PubMed、Embase、Web of Science等数据库,纳入相关文献,使用随机效应模型进行荟萃分析。最终共纳入了28篇文章进行荟萃分析,其中7篇横断面研究(n = 20,111)、8篇病例对照研究(n = 10,815)、13篇队列研究(n = 443,199)。研究数据显示,当前吸烟会增加腰神经根痛或经临床验证的坐骨神经痛风险(合并后

当前关于吸烟对坐骨神经痛的影响仍不明确,研究者检索了PubMed、Embase、Web of Science等数据库,纳入相关文献,使用随机效应模型进行荟萃分析。

最终共纳入了28篇文章进行荟萃分析,其中7篇横断面研究(n = 20,111)、8篇病例对照研究(n = 10,815)、13篇队列研究(n = 443,199)。研究数据显示,当前吸烟会增加腰神经根痛或经临床验证的坐骨神经痛风险(合并后OR 1.46; 95% CI, 1.30-1.64, n = 459,023)。先前吸烟与从未吸烟的人群相比,只会轻度增加风险(aOR 1.15; 95% CI, 1.02-1.30, n = 387,196)。目前吸烟对腰神经根痛风险aOR=1.64 (95% CI, 1.24-2.16, n = 10,853),经临床验证的坐骨神经痛风险aOR=1.35 (95% CI, 1.09-1.68, n = 110,374),因椎间盘突出或坐骨神经痛需要住院或手术风险aOR=1.45 (95% CI, 1.16-1.80, n = 337,796);过去吸烟对以上三种情况风险分别为aOR=1.57 (95% CI, 0.98-2.52)、aOR=1.09 (95% CI, 1.00-1.19)和aOR=1.10 (95% CI, 0.96-1.26)。无论性别均成立。

荟萃分析结果表明,吸烟会适度增加腰神经根痛和经临床验证的坐骨神经痛风险。戒烟可以降低风险,但不能消除风险。

原始出处:

Shiri R, Falah-Hassani K,et al.The Effect of Smoking on the Risk of Sciatica: A Meta-analysis.Am J Med. 2016 Jan;129(1):64-73.e20.

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    2016-02-16 mengli1984

    吸烟危害大

    0

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    2016-01-16 贵阳
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    2016-01-15 zhaofachaofa

    吸烟坏处多,

    0

  7. 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    2016-01-15 wzf990214

    0

  8. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRiaKicWybj5Q5KN7PWibALciaJ4W5bZwTlDSFRibFu87125pCq0IXePrC0mpbiasADRqL4NcjUoyQCT9De/0, createdBy=7c7e1636498, createdName=wzf990214, createdTime=Fri Jan 15 07:05:00 CST 2016, time=2016-01-15, status=1, ipAttribution=)]
    2016-01-15 wzf990214

    0

  9. 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    2016-01-15 wzf990214

    有意思

    0

  10. 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    2016-01-15 wzf990214

    0

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有研究表明女性吸烟会导致不孕不育,影响自然绝经年龄,但是女性暴露二手烟(SHS)呢?研究者对WHI OS研究数据进行了一个全面量化的二次数据分析。以探究烟草暴露(吸烟和二手烟)与不孕不育和自然绝经年龄(<50岁)的联系。该研究数据来自美国40个城市1993-1998年间50-79岁的93676名绝经女性,采集参与者吸烟、生育、自然绝经年龄到呢个资料。校正混杂因素后多因素回归分析主动吸烟和二手烟相关

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全球鼻咽癌发病率很低,但在北非和东南亚非常高,尤其是中国广东!烟草会导致头颈部癌症,但目前没有报道称吸烟和鼻咽癌间的联系。研究者对广州的数据进行了一项前瞻性研究,探究鼻咽癌高发地区吸烟和鼻咽癌死亡率的关系。研究采集了1988年3月-1992年12月的人口统计学资料、吸烟情况等数据,以及直到1999年参与者状态和死因数据。使用Cox风险比例模型分析吸烟和鼻咽癌死亡率间联系。该研究共纳入101,823

BMJ研究新闻:在限制年轻成人社交吸烟时,禁烟令比提高烟草税更有效

据美国的一项研究显示,全面的公共场合禁烟较提高烟草税可更有效的限制年轻成年吸烟,显示了我们的研究,但是研究还发现,对于重度吸烟者提高烟草税的效果更好。

Am J Med:患肺炎的重度吸烟者中肺癌发生率高达9%!

在美国肺癌位居癌症死亡率首位,5年生存率只有17%。吸烟导致了约85%的肺癌病例,只有15%的患者能够做到早期诊断。新研究表明,对重度吸烟的社区获得性肺炎进行肺癌筛查,可能有助于肺癌的早期诊断,从而降低死亡率。患有肺炎的重度吸烟者是肺癌高危人群,应及早进行胸部CT筛查肺癌。肺癌是进展性疾病,只有在症状出现前识别肺癌进行早治疗才能有康复的机会。先前有研究表明,对重度吸烟者进行一年一次的低剂量CT筛查

PLOS ONE:香烟盒上的图像警告信息更有助于吸烟者戒烟

观察性研究表明,香烟盒上印制带有吸烟警告的图案可以降低吸烟率,但是这些研究缺乏实验对照组。本研究采用随机临床试验设计,旨在吸烟者在面对吸烟警告图片和仅面对文字警告时的不同心理过程,试验时间为4周。通过检查对吸烟的影响,警告信息的可靠度,风险认知,戒烟的倾向,对警告标签的记忆,以及吸烟风险的认知来检测图像警告理论的影响效果。