J Clin Periodontol:刮治和根面平整、甲硝唑、阿莫西林治疗糖尿病及非糖尿病牙周炎的临床及微生物学研究

2018-11-17 MedSci MedSci原创

本文旨在评估患或不患糖尿病的牙周炎受试者接受刮治和根面平整(SRP),甲硝唑(MTZ)和阿莫西林(AMX)治疗后效果是否有差别。

本文旨在评估患或不患糖尿病的牙周炎受试者接受刮治和根面平整(SRP),甲硝唑(MTZ)和阿莫西林(AMX)治疗后效果是否有差别。

方法:患或不患糖尿病的重度牙周炎受试者接受SRP + MTZ(400mg /每天三次[TID])+ AMX(500mg / TID)持续14天。通过棋盘DNA-DNA杂交分析龈下生物膜样品中的40种细菌种类。在治疗前,治疗后3,6和12个月四个时间点进行检测。

结果:本研究共有29名2型糖尿病患者和29名非糖尿病患者参加。在非糖尿病患者和糖尿病患者中,68.9%和75.9%分别在治疗后1年达到临床终点(≤4个位点的探诊深度[PD]≥5mm)(p> 0.05)。与非糖尿病组相比,糖尿病组从初始值到治疗后1年,平均临床附着水平增加较少,红色和橙色复合物的比例较高(p <0.05)。

在实现临床治疗终点和PD改善方面,患有重度牙周炎的非糖尿病受试者接受SRP + MTZ + AMX治疗后没有比2型糖尿病受试者达到更好的效果。与非糖尿病患者相比,糖尿病受试者微生物反应与牙龈退缩相关的愈合过程略差。

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    2019-04-02 feather89
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    2018-11-19 whmdzju
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    2018-11-18 misszhang

    谢谢MedSci提供最新的资讯

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=1991179, encodeId=314f19911e946, content=<a href='/topic/show?id=b29c99594dd' target=_blank style='color:#2F92EE;'>#非糖尿病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99594, encryptionId=b29c99594dd, topicName=非糖尿病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=467c360, createdName=yuanming7, createdTime=Tue Jan 15 00:48:00 CST 2019, time=2019-01-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1727734, encodeId=f2571e2773447, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Tue Apr 02 09:48:00 CST 2019, time=2019-04-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1688198, encodeId=1a9a168819864, content=<a href='/topic/show?id=c7a75068505' target=_blank style='color:#2F92EE;'>#微生物学#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50685, encryptionId=c7a75068505, topicName=微生物学)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=27b028484196, createdName=1249883fm21暂无昵称, createdTime=Thu Sep 26 21:48:00 CST 2019, time=2019-09-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1824997, encodeId=8670182499e25, content=<a href='/topic/show?id=702a5065860' target=_blank style='color:#2F92EE;'>#微生物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50658, encryptionId=702a5065860, topicName=微生物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0b7c20, createdName=wjcjjian, createdTime=Tue Dec 04 04:48:00 CST 2018, time=2018-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1299293, encodeId=e02712992938f, content=<a href='/topic/show?id=5413699307e' target=_blank style='color:#2F92EE;'>#甲硝唑#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69930, encryptionId=5413699307e, topicName=甲硝唑)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3860283, createdName=whmdzju, createdTime=Mon Nov 19 12:48:00 CST 2018, time=2018-11-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1451069, encodeId=0054145106984, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=医者仁心, createdTime=Mon Nov 19 12:48:00 CST 2018, time=2018-11-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1617878, encodeId=f801161e8786d, content=<a href='/topic/show?id=e88f6930185' target=_blank style='color:#2F92EE;'>#生物学#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69301, encryptionId=e88f6930185, topicName=生物学)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e44019811593, createdName=12498c32m74暂无昵称, createdTime=Mon Nov 19 12:48:00 CST 2018, time=2018-11-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1042045, encodeId=aeff104204593, content=谢谢MedSci提供最新的资讯, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Sun Nov 18 00:48:00 CST 2018, time=2018-11-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=352897, encodeId=d95735289e05, content=了解一下,谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Sat Nov 17 23:03:15 CST 2018, time=2018-11-17, status=1, ipAttribution=)]
    2018-11-17 天地飞扬

    了解一下,谢谢分享!

    0

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在之前的一项初步研究中,一次性将抗牙龈卟啉单胞菌蛋白免疫球蛋白(IgY)应用于刮治和根面平整(SRP)治疗后的牙周袋,显示慢性牙周炎患者的临床和细菌学参数有了显着改善。本研究旨在评价抗体强化的含片作为牙周炎非手术治疗的辅助治疗的疗效。

J Clin Periodontol:牙周炎与阿尔茨海默病风险、轻度认知障碍和主观认知功能减退的关系

本实验旨在检测牙周病是否可以导致轻度认知功能障碍(MCI),主观认知能力下降(SCD)和阿尔茨海默病(AD)风险增加。