Neurology:脑出血后急性期血压变化的种族差异

2016-10-29 MedSci MedSci原创

目的:评估脑出血(ICH)后急性血压(BP)的种族差异, ICH后的这种差异对预后的影响。方法: 在脑出血种族差异的病例对照研究中,比较非西班牙裔黑人(黑人),非西班牙裔白人(白人)和西班牙裔受试者在现场(急救医疗服务,急诊科(ED))及入院24小时血压。BPS在现场(,并在24小时内进行比较和调整组间差异(黑色),,在脑出血的病例对照研究的少数种族差异。应用3个月改良的Rankin Scale(

目的:评估脑出血(ICH)后急性血压(BP)的种族差异, ICH后的这种差异对预后的影响。

方法: 在脑出血种族差异的病例对照研究中,比较非西班牙裔黑人(黑人),非西班牙裔白人(白人)和西班牙裔受试者在现场(急救医疗服务,急诊科(ED))及入院24小时血压。
BPS在现场(,并在24小时内进行比较和调整组间差异(黑色),,在脑出血的病例对照研究的少数种族差异。应用3个月改良的Rankin Scale(mRS)得到的预后。校正基线差异,研究者分析良好预后(mRS≤2)和死亡的种族差异。

结果:在2069例脑出血患者中,30%例为白人,37%为黑人,33%为西班牙裔人。黑人和西班牙裔患者比白人患者有较高的EMS和ED的收缩压和舒张压(P = 0.0001)。入院24小时后,黑人患者有较高的收缩压和舒张压。调整基线差异,EMS收缩压,ED收缩压和舒张压及24小时舒张压存在种族/民族差异。只有ED收缩压和舒张压与不良预后相关,并没有血压预测死亡。校正组间差异,包括急性血压,研究发现3个月的功能预后和死亡率无种族差异。

结论:虽然黑人和西班牙裔患者比白人患者在基点呈现较高的血压,研究者发现3个月功能预后和死亡率无种族差异。不同种族的人群中,ED收缩压和舒张压与功能预后不良有关,但与死亡无关。

原始出处:

Koch S, Elkind MS, et al. Racial-ethnic disparities in acute blood pressure after intracerebral hemorrhage. Neurology. 2016 Aug 23.


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