孕期甲状腺激素影响胎儿智商!

2015-03-09 佚名 生物谷

    最近一项研究发现,在妊娠早期母亲甲状腺激素水平偏高可能会显著降低婴儿在儿童期的智商。这项研究的结果暗示人们目前治疗孕期女性轻微甲状腺激素缺陷的治疗方法可能会对胎儿脑发育造成意想不到的不良影响。   在之前的研究中发现孕期妇女甲状腺激素偏低可能导致胎儿智商偏低,因此美国甲状腺协会在2011年制订的以及内分泌学会在2012年制订的治疗守则对孕期

   
最近一项研究发现,在妊娠早期母亲甲状腺激素水平偏高可能会显著降低婴儿在儿童期的智商。这项研究的结果暗示人们目前治疗孕期女性轻微甲状腺激素缺陷的治疗方法可能会对胎儿脑发育造成意想不到的不良影响。
 
在之前的研究中发现孕期妇女甲状腺激素偏低可能导致胎儿智商偏低,因此美国甲状腺协会在2011年制订的以及内分泌学会在2012年制订的治疗守则对孕期女性亚临床型甲状腺功能减退症进行了推荐治疗,并且对于治疗该疾病大家已经达成共识,并普遍认为治疗的潜在利益大于过度治疗带来的潜在风险,但该研究发现甲状腺激素的轻微过度也会造成不良影响。
 
研究人员对3839对母子进行了数据评估,在怀孕9到18周,对怀孕母亲进行了血液检查,测量其促甲状腺激素(TSH)以及T4甲状腺激素水平,并对参与研究的5到8岁的儿童进行了IQ检测。研究人员将母亲的T4甲状腺激素水平进行了高低排列,结果发现当母亲的活性T4甲状腺激素水平处于所有检测数值89%以上(也即正常水平偏高阶段),其孩子的智商,比母亲的T4甲状腺激素处于正常水平中间段的孩子平均高出2.1到3.8分。而当母亲的T4甲状腺激素水平处于低于8%水平,其孩子的IQ水平也出现类似的降低。
 
这项研究表明,孕期补充甲状腺激素可能存在过度治疗风险,因此医生在为孕期女性补充甲状腺激素时应更加小心。

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  1. [GetPortalCommentsPageByObjectIdResponse(id=27126, encodeId=ef4e2e126e8, content=好好学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=173, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=ac181616815, createdName=ljjj1053, createdTime=Thu Jun 11 18:50:00 CST 2015, time=2015-06-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=27127, encodeId=3c4f2e127b4, content=好好学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=ac181616815, createdName=ljjj1053, createdTime=Thu Jun 11 18:50:00 CST 2015, time=2015-06-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=18346, encodeId=776c18346eb, content=翻译错误。应该是低了2.1-3.8, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKT7Exm9wh9wsVDUxNuicyfcsIlwSMQjeu0bnzjBBXuXgCq0GxthROPNEmfhfLpCZC3qDjpSK7LeyA/132, createdBy=67811617930, createdName=dreamslink, createdTime=Sun Mar 15 13:20:00 CST 2015, time=2015-03-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=18138, encodeId=ded018138d8, content=The researchers found that the average nonverbal IQ of the children significantly decreased 2.1 to 3.8 points below the average of the reference group (those with free T4 levels in the middle of the range) when the mothers' free T4 level was at or above the 89th percentile., beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160714/IMG5786F4E4B293A5717.jpg, createdBy=92b21616283, createdName=fantasticer, createdTime=Thu Mar 12 08:53:00 CST 2015, time=2015-03-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1322964, encodeId=a5581322964dd, content=<a href='/topic/show?id=a38660034ac' target=_blank style='color:#2F92EE;'>#智商#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=60034, encryptionId=a38660034ac, topicName=智商)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5712500001, createdName=晓辰, createdTime=Wed Mar 11 04:43:00 CST 2015, time=2015-03-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=18064, encodeId=76a118064d4, content=没看明白,文章里面不是说T4水平高于正常值的母亲,其孩子智商偏高吗?, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=58.243.254.**, createdTime=Tue Mar 10 09:29:00 CST 2015, time=2015-03-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=18065, encodeId=489c180659c, content=没看明白,文章里面不是说T4水平高于正常值的母亲,其孩子智商偏高吗?, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=58.243.254.**, createdTime=Tue Mar 10 09:29:00 CST 2015, time=2015-03-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=18015, encodeId=5b05180159a, content=这项研究表明,孕期补充甲状腺激素可能存在过度治疗风险,因此医生在为孕期女性补充甲状腺激素时应更加小心。, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=117.136.8.**, createdTime=Mon Mar 09 17:25:00 CST 2015, time=2015-03-09, status=1, ipAttribution=)]
    2015-06-11 ljjj1053

    好好学习一下

    0

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    2015-06-11 ljjj1053

    好好学习一下

    0

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    2015-03-15 dreamslink

    翻译错误。应该是低了2.1-3.8

    0

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    2015-03-12 fantasticer

    The researchers found that the average nonverbal IQ of the children significantly decreased 2.1 to 3.8 points below the average of the reference group (those with free T4 levels in the middle of the range) when the mothers' free T4 level was at or above the 89th percentile.

    0

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    2015-03-11 晓辰
  6. [GetPortalCommentsPageByObjectIdResponse(id=27126, encodeId=ef4e2e126e8, content=好好学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=173, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=ac181616815, createdName=ljjj1053, createdTime=Thu Jun 11 18:50:00 CST 2015, time=2015-06-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=27127, encodeId=3c4f2e127b4, content=好好学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=ac181616815, createdName=ljjj1053, createdTime=Thu Jun 11 18:50:00 CST 2015, time=2015-06-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=18346, encodeId=776c18346eb, content=翻译错误。应该是低了2.1-3.8, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKT7Exm9wh9wsVDUxNuicyfcsIlwSMQjeu0bnzjBBXuXgCq0GxthROPNEmfhfLpCZC3qDjpSK7LeyA/132, createdBy=67811617930, createdName=dreamslink, createdTime=Sun Mar 15 13:20:00 CST 2015, time=2015-03-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=18138, encodeId=ded018138d8, content=The researchers found that the average nonverbal IQ of the children significantly decreased 2.1 to 3.8 points below the average of the reference group (those with free T4 levels in the middle of the range) when the mothers' free T4 level was at or above the 89th percentile., beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160714/IMG5786F4E4B293A5717.jpg, createdBy=92b21616283, createdName=fantasticer, createdTime=Thu Mar 12 08:53:00 CST 2015, time=2015-03-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1322964, encodeId=a5581322964dd, content=<a href='/topic/show?id=a38660034ac' target=_blank style='color:#2F92EE;'>#智商#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=60034, encryptionId=a38660034ac, topicName=智商)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5712500001, createdName=晓辰, createdTime=Wed Mar 11 04:43:00 CST 2015, time=2015-03-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=18064, encodeId=76a118064d4, content=没看明白,文章里面不是说T4水平高于正常值的母亲,其孩子智商偏高吗?, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=58.243.254.**, createdTime=Tue Mar 10 09:29:00 CST 2015, time=2015-03-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=18065, encodeId=489c180659c, content=没看明白,文章里面不是说T4水平高于正常值的母亲,其孩子智商偏高吗?, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=58.243.254.**, createdTime=Tue Mar 10 09:29:00 CST 2015, time=2015-03-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=18015, encodeId=5b05180159a, content=这项研究表明,孕期补充甲状腺激素可能存在过度治疗风险,因此医生在为孕期女性补充甲状腺激素时应更加小心。, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=117.136.8.**, createdTime=Mon Mar 09 17:25:00 CST 2015, time=2015-03-09, status=1, ipAttribution=)]
    2015-03-10 58.243.254.**

    没看明白,文章里面不是说T4水平高于正常值的母亲,其孩子智商偏高吗?

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=27126, encodeId=ef4e2e126e8, content=好好学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=173, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=ac181616815, createdName=ljjj1053, createdTime=Thu Jun 11 18:50:00 CST 2015, time=2015-06-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=27127, encodeId=3c4f2e127b4, content=好好学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=ac181616815, createdName=ljjj1053, createdTime=Thu Jun 11 18:50:00 CST 2015, time=2015-06-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=18346, encodeId=776c18346eb, content=翻译错误。应该是低了2.1-3.8, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKT7Exm9wh9wsVDUxNuicyfcsIlwSMQjeu0bnzjBBXuXgCq0GxthROPNEmfhfLpCZC3qDjpSK7LeyA/132, createdBy=67811617930, createdName=dreamslink, createdTime=Sun Mar 15 13:20:00 CST 2015, time=2015-03-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=18138, encodeId=ded018138d8, content=The researchers found that the average nonverbal IQ of the children significantly decreased 2.1 to 3.8 points below the average of the reference group (those with free T4 levels in the middle of the range) when the mothers' free T4 level was at or above the 89th percentile., beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160714/IMG5786F4E4B293A5717.jpg, createdBy=92b21616283, createdName=fantasticer, createdTime=Thu Mar 12 08:53:00 CST 2015, time=2015-03-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1322964, encodeId=a5581322964dd, content=<a href='/topic/show?id=a38660034ac' target=_blank style='color:#2F92EE;'>#智商#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=60034, encryptionId=a38660034ac, topicName=智商)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5712500001, createdName=晓辰, createdTime=Wed Mar 11 04:43:00 CST 2015, time=2015-03-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=18064, encodeId=76a118064d4, content=没看明白,文章里面不是说T4水平高于正常值的母亲,其孩子智商偏高吗?, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=58.243.254.**, createdTime=Tue Mar 10 09:29:00 CST 2015, time=2015-03-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=18065, encodeId=489c180659c, content=没看明白,文章里面不是说T4水平高于正常值的母亲,其孩子智商偏高吗?, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=58.243.254.**, createdTime=Tue Mar 10 09:29:00 CST 2015, time=2015-03-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=18015, encodeId=5b05180159a, content=这项研究表明,孕期补充甲状腺激素可能存在过度治疗风险,因此医生在为孕期女性补充甲状腺激素时应更加小心。, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=117.136.8.**, createdTime=Mon Mar 09 17:25:00 CST 2015, time=2015-03-09, status=1, ipAttribution=)]
    2015-03-10 58.243.254.**

    没看明白,文章里面不是说T4水平高于正常值的母亲,其孩子智商偏高吗?

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=27126, encodeId=ef4e2e126e8, content=好好学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=173, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=ac181616815, createdName=ljjj1053, createdTime=Thu Jun 11 18:50:00 CST 2015, time=2015-06-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=27127, encodeId=3c4f2e127b4, content=好好学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=ac181616815, createdName=ljjj1053, createdTime=Thu Jun 11 18:50:00 CST 2015, time=2015-06-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=18346, encodeId=776c18346eb, content=翻译错误。应该是低了2.1-3.8, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKT7Exm9wh9wsVDUxNuicyfcsIlwSMQjeu0bnzjBBXuXgCq0GxthROPNEmfhfLpCZC3qDjpSK7LeyA/132, createdBy=67811617930, createdName=dreamslink, createdTime=Sun Mar 15 13:20:00 CST 2015, time=2015-03-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=18138, encodeId=ded018138d8, content=The researchers found that the average nonverbal IQ of the children significantly decreased 2.1 to 3.8 points below the average of the reference group (those with free T4 levels in the middle of the range) when the mothers' free T4 level was at or above the 89th percentile., beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160714/IMG5786F4E4B293A5717.jpg, createdBy=92b21616283, createdName=fantasticer, createdTime=Thu Mar 12 08:53:00 CST 2015, time=2015-03-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1322964, encodeId=a5581322964dd, content=<a href='/topic/show?id=a38660034ac' target=_blank style='color:#2F92EE;'>#智商#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=60034, encryptionId=a38660034ac, topicName=智商)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5712500001, createdName=晓辰, createdTime=Wed Mar 11 04:43:00 CST 2015, time=2015-03-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=18064, encodeId=76a118064d4, content=没看明白,文章里面不是说T4水平高于正常值的母亲,其孩子智商偏高吗?, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=58.243.254.**, createdTime=Tue Mar 10 09:29:00 CST 2015, time=2015-03-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=18065, encodeId=489c180659c, content=没看明白,文章里面不是说T4水平高于正常值的母亲,其孩子智商偏高吗?, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=58.243.254.**, createdTime=Tue Mar 10 09:29:00 CST 2015, time=2015-03-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=18015, encodeId=5b05180159a, content=这项研究表明,孕期补充甲状腺激素可能存在过度治疗风险,因此医生在为孕期女性补充甲状腺激素时应更加小心。, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=117.136.8.**, createdTime=Mon Mar 09 17:25:00 CST 2015, time=2015-03-09, status=1, ipAttribution=)]
    2015-03-09 117.136.8.**

    这项研究表明,孕期补充甲状腺激素可能存在过度治疗风险,因此医生在为孕期女性补充甲状腺激素时应更加小心。

    0

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