Lancet Diabetes Endo:服用雌激素和抗雄激素类变性为女性的风险

2017-05-11 贾朝娟 环球医学

变性为女性者的治疗会引起哪些身体变化,有什么样的获益和风险,2017年4月,发表在《Lancet Diabetes Endocrinol》的一篇文章对此进行了详细阐述。变性为女性者会出现终身性别方面的焦虑,这是因为出生时的性别与其性别认同不一致。她们常常寻求激素疗法联合或不联合手术,改善性别交流,并更好地使其身体和心理特征更具有女性化。雌激素和抗雄激素治疗引起的一些身体变化包括体重减少和胡须减少、

变性为女性者的治疗会引起哪些身体变化,有什么样的获益和风险,2017年4月,发表在《Lancet Diabetes Endocrinol》的一篇文章对此进行了详细阐述。

变性为女性者会出现终身性别方面的焦虑,这是因为出生时的性别与其性别认同不一致。她们常常寻求激素疗法联合或不联合手术,改善性别交流,并更好地使其身体和心理特征更具有女性化。雌激素和抗雄激素治疗引起的一些身体变化包括体重减少和胡须减少、降低肌肉质量、胸部发育和脂肪再分布。总体治疗风险较低,但风险包括血栓栓塞,这一风险取决于雌激素给药的剂量和途径。在变性为女性中常会见到其他相关症状,包括抑郁和骨质疏松风险的增加。变性为女性的激素敏感性癌症风险似乎较低,同女性相比不会增加乳腺癌风险,同男性相比不会增加膀胱癌风险。由于缺乏高质量研究,变性为女性治疗的证据基础有限,需要长期纵向研究来指导实践。

原始出处:

Tangpricha V, den Heijer M. Oestrogen and anti-androgen therapy for transgender women. Lancet Diabetes Endocrinol. 2017 Apr。

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    2017-07-25 howi
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    2017-05-14 lou.minghong

    学习

    0

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    2017-05-13 186****0580(小山羊)

    学习了谢谢了。

    0

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    2017-05-13 huangdf
  8. [GetPortalCommentsPageByObjectIdResponse(id=1759966, encodeId=950b1e5996660, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9a1a37427546, createdName=ms5439512287675881, createdTime=Thu Sep 07 03:12:00 CST 2017, time=2017-09-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1637732, encodeId=bed5163e7328a, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Mon Jun 26 20:12:00 CST 2017, time=2017-06-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1901637, encodeId=1ca5190163eaf, content=<a href='/topic/show?id=c097591ed5' target=_blank style='color:#2F92EE;'>#Diabetes#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5917, encryptionId=c097591ed5, topicName=Diabetes)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0045169, createdName=木头人513, createdTime=Sat Oct 28 18:12:00 CST 2017, time=2017-10-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1828939, encodeId=f2521828939f8, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Tue Jul 25 21:12:00 CST 2017, time=2017-07-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=197759, encodeId=7d2919e759b0, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib2JlGvwpAibiaovVhfA9DbO7X7JLGGjM4Cic6oMgxLdnuS9piaP9cnG2OwIbkzHvX0qzS1boibyYNqR5vHZu7HQs5EIB/0, createdBy=298d1398341, createdName=lou.minghong, createdTime=Sun May 14 04:22:44 CST 2017, time=2017-05-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=197513, encodeId=720619e513d9, content=学习了谢谢了。, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLPeNmuNF9ibgMfMOAs7Iic5MpiaU8RLmRH67xCKuk5wzfhb7G4ib7ia6z9lrnsTicj1nAUfEOMecZDtvvu/0, createdBy=d7f91939785, createdName=186****0580(小山羊), createdTime=Sat May 13 10:24:11 CST 2017, time=2017-05-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1463528, encodeId=3da71463528f5, content=<a href='/topic/show?id=7d27381288e' target=_blank style='color:#2F92EE;'>#变性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38128, encryptionId=7d27381288e, topicName=变性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f69f6545041, createdName=huangdf, createdTime=Sat May 13 08:12:00 CST 2017, time=2017-05-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=197018, encodeId=076d19e0182d, content=文章不错,拜读了, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Fri May 12 10:03:42 CST 2017, time=2017-05-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=196986, encodeId=7822196986c1, content=学习,感谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyhb9xDeHojCicsdRdyC3XXdGk2ib9yLypZuHN06WeW4HO8WN0GGrgEfvnTX8gsckof05GHOU5OM4Mvx/0, createdBy=9cee1982656, createdName=执着追梦, createdTime=Fri May 12 08:54:35 CST 2017, time=2017-05-12, status=1, ipAttribution=)]
    2017-05-12 1e10c84am36(暂无匿称)

    文章不错,拜读了

    0

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    2017-05-12 执着追梦

    学习,感谢分享!

    0

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