JAHA:急性缺血性卒中后低脉压与不良预后有关!

2017-06-22 xing.T MedSci原创

由此可见,入院时低脉压与AIS患者不良预后相关。

脉压与心功能、动脉僵硬度、体液状态和血管事件有关。近日,心血管疾病领域权威杂志JAHA上发表了一篇研究文章,研究人员旨在探讨基于全台湾范围内卒中登记中心的急性缺血性卒中(AIS)患者入院时的脉压在患者预后判断中的作用。

研究人员评估了入院时脉压与AIS患者3个月之后结局之间的相关性,这些患者来自于2006年至2013年期间台湾卒中登记中心,所涉及56个教学医院和社区医院。脑卒中后三个月,不利的结局被定义为采用改进的Rankin量表得分为3-6分。

该研究纳入了33530例AIS患者(女性占40.6%;平均年龄为68.8±13.3岁),研究人员发现参与者入院时的脉压与患者不利结局之间存在反J-曲线的相关性。对临床变量进行调整后,这些变量包括AIS亚型、初始NIHSS评分、入院时收缩压和舒张压,研究人员发现脉压<50mmHg与不良结局相关(P<0.0001)。与脉压为50至69 mmHg的患者相比,脉压为30至49mmHg的患者不利结局的比值比为1.24(95%可信区间为1.14-1.36),而脉压<30mmHg的患者不利结局的比值比为1.85(95%可信区间为1.50-2.28)。此外,入院时脉压在所有AIS亚型中对预后的影响较为相似。

由此可见,入院时低脉压与AIS患者不良预后相关。

原始出处:

Sung‐Chun Tang,et al. Low Pulse Pressure After Acute Ischemic Stroke is Associated With Unfavorable Outcomes: The Taiwan Stroke Registry.JAHA.2017. https://doi.org/10.1161/JAHA.116.005113

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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5Kzuf9u71gZhPYMiajRtENwicoAABeQtfXOlic8ibhYSy6DvJZWUDVtjRvTfqBffr1XJ6JLtFB5kHicthl/0, createdBy=08bb2061153, createdName=189****7206, createdTime=Fri Jun 23 00:04:26 CST 2017, time=2017-06-23, status=1, ipAttribution=)]
    2017-06-24 zhaohui6731
  5. 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  6. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5Kzuf9u71gZhPYMiajRtENwicoAABeQtfXOlic8ibhYSy6DvJZWUDVtjRvTfqBffr1XJ6JLtFB5kHicthl/0, createdBy=08bb2061153, createdName=189****7206, createdTime=Fri Jun 23 00:04:26 CST 2017, time=2017-06-23, status=1, ipAttribution=)]
    2017-06-23 meiliwuxian

    看来血压要注意了

    0

  7. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5Kzuf9u71gZhPYMiajRtENwicoAABeQtfXOlic8ibhYSy6DvJZWUDVtjRvTfqBffr1XJ6JLtFB5kHicthl/0, createdBy=08bb2061153, createdName=189****7206, createdTime=Fri Jun 23 00:04:26 CST 2017, time=2017-06-23, status=1, ipAttribution=)]
    2017-06-23 jyzxjiangqin

    急性缺血性卒中的治疗。

    0

  8. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5Kzuf9u71gZhPYMiajRtENwicoAABeQtfXOlic8ibhYSy6DvJZWUDVtjRvTfqBffr1XJ6JLtFB5kHicthl/0, createdBy=08bb2061153, createdName=189****7206, createdTime=Fri Jun 23 00:04:26 CST 2017, time=2017-06-23, status=1, ipAttribution=)]
    2017-06-23 baihao215

    脉压地的可能机制是?

    0

  9. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5Kzuf9u71gZhPYMiajRtENwicoAABeQtfXOlic8ibhYSy6DvJZWUDVtjRvTfqBffr1XJ6JLtFB5kHicthl/0, createdBy=08bb2061153, createdName=189****7206, createdTime=Fri Jun 23 00:04:26 CST 2017, time=2017-06-23, status=1, ipAttribution=)]
    2017-06-23 海棠胜雪

    学习了

    0

  10. 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    2017-06-23 189****7206

    学习了受益匪浅

    0

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本研究旨在评估急性缺血性卒中(AIS)患者中使用新的标准化护理协同工作流程的有效性以减少卒中溶栓延迟。研究纳入了2015年3月到9月接受常规溶栓治疗的AIS患者,,作为对照组,简称为T0。干预组简称为T1组,纳入了接受一种新的标准化护理协同工作流程进行静脉溶栓(IVT)的AIS患者,2015年10月至2016年3月就诊于上海东方医院急救部。搜集信息:应用或未溶栓,计算机断层扫描(CT)的时间,和d