BMJ:溶栓治疗并发自发性舌血肿——案例报道

2016-11-17 MedSci MedSci原创

患者男,71岁,静脉阿替普酶和肝素治疗后3小时后,出现言语和吞咽困难。 患者因为肺栓塞引起血流动力学不稳定,所以使用这两种药物治疗,阿替普酶的治疗剂量为10 mg静脉推注,然后90 mg静脉滴注(超过两小时)。 查体发现舌严重肿胀和瘀斑,提示舌血肿。除抗凝/溶栓治疗外,没有发现其他病因。 对患者的气道进行密切监测,最终没有进行干预,患者就自行恢复了。 溶栓治疗过程中

患者男,71岁,静脉阿替普酶和肝素治疗后3小时后,出现言语和吞咽困难。

患者因为肺栓塞引起血流动力学不稳定,所以使用这两种药物治疗,阿替普酶的治疗剂量为10 mg静脉推注,然后90 mg静脉滴注(超过两小时)。

查体发现舌严重肿胀和瘀斑,提示舌血肿。除抗凝/溶栓治疗外,没有发现其他病因。



对患者的气道进行密切监测,最终没有进行干预,患者就自行恢复了。

溶栓治疗过程中大约有5%的患者会出现出血或血肿形成并发症。出血性事件通常限于注射部位,不过临床医生应该意识到,自发性出血还可以发生在其他与注射部位不相关的部位,此外还应注意轻微外伤后的出血风险。

原始出处:

Alexander Bobinskas,et al.Spontaneous lingual haematoma secondary to thrombolysis.BMJ 2016;355:i5569

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    2017-04-01 gaoxiaoe
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    2017-01-08 丁鹏鹏
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    2016-11-19 lqvr
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    2016-11-19 sodoo