Diabetic Med:妊娠期体重增加是否重要?

2019-04-01 不详 网络

<span style="font-size:9.0pt;font-family:宋体;mso-ascii-theme-font:major-fareast; mso-fareast-theme-font:major-fareast;mso-hansi-theme-font:major-fareast; color:black;mso-bidi-font-weight:bold">妊娠期体重增

妊娠期体重增加过多会增加妊娠期糖尿病GDM)的风险,但目前尚不清楚GDM诊断后体重控制是否能改善预后。近日,国际杂志 《Diabetic Med》上在线发表一项关于“改善妊娠期糖尿病的结果:妊娠期体重增加是否重要?的研究。

研究人员评估了以下问题:(1)怀孕期间的总体重增加(0-36周);(2)早期妊娠期体重增加(0-28周,GDM诊断前);或(3)妊娠晚期体重增加(28-36周,诊断后)是否与母胎结局有关。这项回顾性观察性研究纳入了546GDM女性,这些女性在一个英国产科中心(201410月至20173月)分娩了单胎活婴。

研究表明,妊娠期总体重增加与剖腹产 [ n=376; 比值比(OR1.05; 置信区间(CI1.02-1.08P <0.001],孕龄大(OR 1.08; CI 1.03-1.12P <0.001)相关。妊娠晚期体重增加较高(28-36; n = 144)与孕龄较大(OR 1.17; CI 1.01-1.37P <0.05),器械分娩(OR 1.26; CI 1.03-1.55P <0.01),每日胰岛素总剂量较高(36;β系数4.37; CI 1.92-6.82P <0.001),产后2小时口服葡萄糖耐量试验浓度较高(β系数0.12; CI 0.01-0.22P<0.05)相关。与GDM诊断后持续体重增加的女性比较,避免显著体重增加的女性在出生后2小时葡萄糖含量低0.7 mmol/ l,且36周时仅需要一半胰岛素/天。早期妊娠期体重增加(0-28周)与妊娠结局之间无显著相关性。

这些研究结果表明,控制妊娠期体重增加应该是GDM诊断后的优先事项,以优化妊娠结局并改善产妇的产后葡萄糖稳态。

原始出处:

C. E. M. AikenL. HoneH. R. Murphyet al. Improving outcomes in gestational diabetes: does gestational weight gain matter?

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    2019-08-08 jyzxjiangqin

    妊娠期体重管理。

    0

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