Arthritis Care Res:痛风患者警惕**跖趾关节出现骨侵蚀和滑膜炎

2016-10-05 Mechront 译 MedSci原创

最新研究数据显示:痛风患者的第一跖趾关节,很容易出现尿酸盐沉积、滑膜炎、骨侵蚀。 该研究纳入了23例痛风患者、29例无症状性高尿酸血症患者、34例年龄和性别匹配的血尿酸正常者的对照参与。探究这些参与者的第一跖趾关节(MTP)的超声特征。 肌肉骨骼放射科医生通过灰度和能量多普勒超声检查,评估每个参与者的双侧关节。在扫描的时候,所有参与者均没有关节炎。此后,两个肌肉骨骼放射科医师评估静态图

最新研究数据显示:痛风患者的第一跖趾关节,很容易出现尿酸盐沉积、滑膜炎、骨侵蚀。

该研究纳入了23例痛风患者、29例无症状性高尿酸血症患者、34例年龄和性别匹配的血尿酸正常者的对照参与。探究这些参与者的第一跖趾关节(MTP)的超声特征。

肌肉骨骼放射科医生通过灰度和能量多普勒超声检查,评估每个参与者的双侧关节。在扫描的时候,所有参与者均没有关节炎。此后,两个肌肉骨骼放射科医师评估静态图像中的双边征、痛风、侵蚀、积液、滑膜肥厚、滑膜炎和软骨厚度等情况。

与对照组相比,痛风患者(比值比= 3.91)和无症状性高尿酸血症患者(比值比= 3.81),更有可能出现双轮廓标志。痛风患者更可能存在骨侵蚀(比值比= 10.13)和滑膜炎(比值比=9)。此外,痛风石更大的患者,有更大的骨侵蚀直径。与无症状高尿酸血症的参与者相比,痛风患者更可能出现更严重的骨侵蚀和滑膜炎,以及更不严重的积液分级。

研究人员得出结论,与痛风患者相比,虽然无症状高尿酸血症缺乏炎症和关节结构的变化,但是有类似的尿酸盐沉积速率。

原始出处:

Bone erosion commonly found in first MTP joint in patients with gout.Healio.October 4, 2016

Stewart S, et al. Ultrasound features of the first metatarsophalangeal joint in gout and asymptomatic hyperuricaemia: Comparison with normouricaemic individuals.Arthritis Care Res (Hoboken). 2016;doi:10.1002/acr.23082.

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    2016-10-07 zhaojie88
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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=140395, encodeId=707d140395a9, content=加强警惕性!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Pw2csslt7CukWiabqiblnQAXaDEiaxhu025c3P0XshccTrbvGWBjKvnHIxbK3vqa80P7WGIFuicCFet97TicrNKpgB3TdabxP1vMh/0, createdBy=28851960965, createdName=榄枷檬, createdTime=Wed Oct 05 15:12:53 CST 2016, time=2016-10-05, status=1, ipAttribution=)]
    2016-10-07 pcw106
  4. 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content=學習啦,,, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfdY7yem1P7bRvOP6z0jKsBoYR8ezfAricY7meQWcte7LRJsWHVn0CnPJg2JuQmevR0DoFmmEib5QLD2kNESBESQT/0, createdBy=59191706502, createdName=医路开来, createdTime=Thu Oct 06 14:28:37 CST 2016, time=2016-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=141096, encodeId=037514109663, content=:痛风患者警惕第一跖趾关节出现骨侵蚀和滑膜炎, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfdY7yem1P7bRvOP6z0jKsBoYR8ezfAricY7meQWcte7LRJsWHVn0CnPJg2JuQmevR0DoFmmEib5QLD2kNESBESQT/0, createdBy=59191706502, createdName=医路开来, createdTime=Thu Oct 06 14:28:18 CST 2016, time=2016-10-06, status=1, 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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=140395, encodeId=707d140395a9, content=加强警惕性!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Pw2csslt7CukWiabqiblnQAXaDEiaxhu025c3P0XshccTrbvGWBjKvnHIxbK3vqa80P7WGIFuicCFet97TicrNKpgB3TdabxP1vMh/0, createdBy=28851960965, createdName=榄枷檬, createdTime=Wed Oct 05 15:12:53 CST 2016, time=2016-10-05, status=1, ipAttribution=)]
  5. 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objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101588, encryptionId=6b6b101588c6, topicName=骨侵蚀)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=69e219671853, createdName=ms9608593228839890, createdTime=Fri Oct 07 06:07:00 CST 2016, time=2016-10-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=141098, encodeId=fef1141098fb, content=謝謝分享,,, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfdY7yem1P7bRvOP6z0jKsBoYR8ezfAricY7meQWcte7LRJsWHVn0CnPJg2JuQmevR0DoFmmEib5QLD2kNESBESQT/0, createdBy=59191706502, createdName=医路开来, createdTime=Thu Oct 06 14:28:46 CST 2016, time=2016-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=141097, encodeId=403814109e06, 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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=140418, encodeId=235b140418b2, content=总结的很好!, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160817/IMG57B3C3F6DC2FD8753.jpg, createdBy=81321934679, createdName=1e0d99ddm02(暂无匿称), createdTime=Wed Oct 05 15:43:48 CST 2016, time=2016-10-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=140416, encodeId=dae4140416a5, content=学习了,分享一下!, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160817/IMG57B3C3F6DC2FD8753.jpg, createdBy=81321934679, createdName=1e0d99ddm02(暂无匿称), createdTime=Wed Oct 05 15:43:28 CST 2016, time=2016-10-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=140395, encodeId=707d140395a9, content=加强警惕性!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Pw2csslt7CukWiabqiblnQAXaDEiaxhu025c3P0XshccTrbvGWBjKvnHIxbK3vqa80P7WGIFuicCFet97TicrNKpgB3TdabxP1vMh/0, createdBy=28851960965, createdName=榄枷檬, createdTime=Wed Oct 05 15:12:53 CST 2016, time=2016-10-05, status=1, ipAttribution=)]
    2016-10-06 医路开来

    謝謝分享,,

    0

  6. 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content=學習啦,,, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfdY7yem1P7bRvOP6z0jKsBoYR8ezfAricY7meQWcte7LRJsWHVn0CnPJg2JuQmevR0DoFmmEib5QLD2kNESBESQT/0, createdBy=59191706502, createdName=医路开来, createdTime=Thu Oct 06 14:28:37 CST 2016, time=2016-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=141096, encodeId=037514109663, content=:痛风患者警惕第一跖趾关节出现骨侵蚀和滑膜炎, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfdY7yem1P7bRvOP6z0jKsBoYR8ezfAricY7meQWcte7LRJsWHVn0CnPJg2JuQmevR0DoFmmEib5QLD2kNESBESQT/0, createdBy=59191706502, createdName=医路开来, createdTime=Thu Oct 06 14:28:18 CST 2016, time=2016-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=140418, encodeId=235b140418b2, content=总结的很好!, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160817/IMG57B3C3F6DC2FD8753.jpg, createdBy=81321934679, createdName=1e0d99ddm02(暂无匿称), createdTime=Wed Oct 05 15:43:48 CST 2016, time=2016-10-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=140416, encodeId=dae4140416a5, content=学习了,分享一下!, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160817/IMG57B3C3F6DC2FD8753.jpg, createdBy=81321934679, createdName=1e0d99ddm02(暂无匿称), createdTime=Wed Oct 05 15:43:28 CST 2016, time=2016-10-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=140395, encodeId=707d140395a9, content=加强警惕性!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Pw2csslt7CukWiabqiblnQAXaDEiaxhu025c3P0XshccTrbvGWBjKvnHIxbK3vqa80P7WGIFuicCFet97TicrNKpgB3TdabxP1vMh/0, createdBy=28851960965, createdName=榄枷檬, createdTime=Wed Oct 05 15:12:53 CST 2016, time=2016-10-05, status=1, ipAttribution=)]
    2016-10-06 医路开来

    學習啦,,

    0

  7. 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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=140395, encodeId=707d140395a9, content=加强警惕性!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Pw2csslt7CukWiabqiblnQAXaDEiaxhu025c3P0XshccTrbvGWBjKvnHIxbK3vqa80P7WGIFuicCFet97TicrNKpgB3TdabxP1vMh/0, createdBy=28851960965, createdName=榄枷檬, createdTime=Wed Oct 05 15:12:53 CST 2016, time=2016-10-05, status=1, ipAttribution=)]
    2016-10-06 医路开来

    :痛风患者警惕第一跖趾关节出现骨侵蚀和滑膜炎

    0

  8. 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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=140418, encodeId=235b140418b2, content=总结的很好!, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160817/IMG57B3C3F6DC2FD8753.jpg, createdBy=81321934679, createdName=1e0d99ddm02(暂无匿称), createdTime=Wed Oct 05 15:43:48 CST 2016, time=2016-10-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=140416, encodeId=dae4140416a5, content=学习了,分享一下!, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160817/IMG57B3C3F6DC2FD8753.jpg, createdBy=81321934679, createdName=1e0d99ddm02(暂无匿称), createdTime=Wed Oct 05 15:43:28 CST 2016, time=2016-10-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=140395, encodeId=707d140395a9, content=加强警惕性!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Pw2csslt7CukWiabqiblnQAXaDEiaxhu025c3P0XshccTrbvGWBjKvnHIxbK3vqa80P7WGIFuicCFet97TicrNKpgB3TdabxP1vMh/0, createdBy=28851960965, createdName=榄枷檬, createdTime=Wed Oct 05 15:12:53 CST 2016, time=2016-10-05, status=1, ipAttribution=)]
    2016-10-05 1e0d99ddm02(暂无匿称)

    总结的很好!

    0

  9. 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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=140395, encodeId=707d140395a9, content=加强警惕性!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Pw2csslt7CukWiabqiblnQAXaDEiaxhu025c3P0XshccTrbvGWBjKvnHIxbK3vqa80P7WGIFuicCFet97TicrNKpgB3TdabxP1vMh/0, createdBy=28851960965, createdName=榄枷檬, createdTime=Wed Oct 05 15:12:53 CST 2016, time=2016-10-05, status=1, ipAttribution=)]
    2016-10-05 1e0d99ddm02(暂无匿称)

    学习了,分享一下!

    0

  10. 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content=學習啦,,, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfdY7yem1P7bRvOP6z0jKsBoYR8ezfAricY7meQWcte7LRJsWHVn0CnPJg2JuQmevR0DoFmmEib5QLD2kNESBESQT/0, createdBy=59191706502, createdName=医路开来, createdTime=Thu Oct 06 14:28:37 CST 2016, time=2016-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=141096, encodeId=037514109663, content=:痛风患者警惕第一跖趾关节出现骨侵蚀和滑膜炎, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfdY7yem1P7bRvOP6z0jKsBoYR8ezfAricY7meQWcte7LRJsWHVn0CnPJg2JuQmevR0DoFmmEib5QLD2kNESBESQT/0, createdBy=59191706502, createdName=医路开来, createdTime=Thu Oct 06 14:28:18 CST 2016, time=2016-10-06, status=1, 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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=140395, encodeId=707d140395a9, content=加强警惕性!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Pw2csslt7CukWiabqiblnQAXaDEiaxhu025c3P0XshccTrbvGWBjKvnHIxbK3vqa80P7WGIFuicCFet97TicrNKpgB3TdabxP1vMh/0, createdBy=28851960965, createdName=榄枷檬, createdTime=Wed Oct 05 15:12:53 CST 2016, time=2016-10-05, status=1, ipAttribution=)]
    2016-10-05 榄枷檬

    加强警惕性!!

    0

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