Stroke:视网膜动脉闭塞与卒中发生相关

2016-05-30 phylis 译 MedSci原创

背景:研究者旨在评估视网膜动脉闭塞(RAO)后,随后的卒中发展的风险。方法:研究者从韩国国民健康保险服务中收集国家登记数据,包括了1025340随机受试者。排除在2002和2003诊断的RAO患者。RAO组在2004年1月到2013年12月最初诊断为中心或其他RAO的患者(n=401)。对照组随机选择的患者(5:1;n = 2003),根据社会人口因素和RAO诊断的年限相匹配。每个采样病人随访直2

背景:研究者旨在评估视网膜动脉闭塞(RAO)后,随后的卒中发展的风险。

方法:研究者从韩国国民健康保险服务中收集国家登记数据,包括了1025340随机受试者。排除在2002和2003诊断的RAO患者。RAO组在2004年1月到2013年12月最初诊断为中心或其他RAO的患者(n=401)。对照组随机选择的患者(5:1;n = 2003),根据社会人口因素和RAO诊断的年限相匹配。每个采样病人随访至2013。使用Cox比例风险回归进行分析。

结果:RAO组和对照组发生卒中的比率分别为15%、8%。RAO与卒中发生风险增加相关(HR,1.78;95% CI,1.32-2.41)。与老年人≥65年相比(HR 1.26), RAO对年轻人<65岁(HR 3.11)卒中的影响幅度较大。然而,在4年的随访后,老年人≥65岁发生卒中的风险显著增加(HR,1.58;95%CI,1.01-2.48)。

结论:校正社会人口学因素和并发症,RAO与卒中发生显著相关。由于不受控制的混杂因素,研究结果具有一定的局限性,需要其他的观察性研究进一步调查。

原始出处:

Rim TH, Han J, et al. Retinal Artery Occlusion and the Risk of Stroke Development: Twelve-Year Nationwide Cohort Study. Stroke. 2016 Feb.


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    2016-10-14 ylzr123

    好文值得点赞!继续关注学习。

    0

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    2016-06-01 zutt
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    2016-05-31 足球疯子

    心灵的窗户呀

    0