BMJ Open:急性,亚急性和慢性咳嗽的风险因素的确定

2018-07-29 MedSci MedSci原创

慢性咳嗽与各种长期风险因素有关,如哮喘,慢性鼻炎和食管反流病。相反,急性和亚急性咳嗽通常被认为是由急性呼吸道感染引起的。目前对于急性和亚急性咳嗽的长期风险因素知之甚少。在本研究中,我们确定了急性,亚急性和慢性咳嗽的长期风险因素,以确定与慢性咳嗽特异性相关的风险因素。研究人员通过电子邮件向参与者发送了一份全面的80项问卷。共纳入了13980名参与者,最后3697名参与者应答(26.4%)。在应答者中

慢性咳嗽与各种长期风险因素有关,如哮喘,慢性鼻炎和食管反流病。相反,急性和亚急性咳嗽通常被认为是由急性呼吸道感染引起的。目前对于急性和亚急性咳嗽的长期风险因素知之甚少。在本研究中,我们确定了急性,亚急性和慢性咳嗽的长期风险因素,以确定与慢性咳嗽特异性相关的风险因素。

研究人员通过电子邮件向参与者发送了一份全面的80项问卷。共纳入了13980名参与者,最后3697名参与者应答(26.4%)。在应答者中,有199名当前每日急性咳嗽(持续时间<3周,患病率为5.4%),126名当前每日亚急性咳嗽(持续时间3-8周,患病率为3.4%),267名当前每日慢性咳嗽的受试者(持续时间> 8周,患病率7.2%)。

结果显示,几种风险因素与短期和长期咳嗽亚型有关,即慢性咳嗽的家族史,环境干燥和其他身体伴随症状的数量。此外,过敏与急性和亚急性咳嗽有关。目前的哮喘和慢性鼻炎与亚急性和慢性咳嗽有关。食管反流病和高龄与慢性咳嗽有关。

综上所述,该研究结果表明,慢性咳嗽的危险因素包括食管反流病和高龄。急性和亚急性咳嗽不应仅仅视为急性呼吸道感染的症状,而是可能表现为长期慢性咳嗽的危险因素。慢性咳嗽的家族史是所有咳嗽类型的新风险因素。

原始出处:

Lätti AM, Pekkanen J, Koskela HO. Defining the risk factors for acute, subacute and chronic cough: a cross-sectional study in a Finnish adult employee population. BMJ Open. 2018 Jul 16;8(7):e022950. doi: 10.1136/bmjopen-2018-022950.

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    2018-10-05 gaoxiaoe
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    2019-05-19 feather89
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    2018-07-30 yjs木玉

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