Radiology:在PET/MRI评价基于深度学习MR成像衰减校准方法的可行性

2017-10-06 shaosai MedSci原创

本研究旨在提高和低价基于磁共振(MR)的深度学习方法衰减校准(AC)(深度MRAC)在颅脑正电子发射体层成像(PET)/MRI的价值,并将结果发表在Radiology上。

本研究旨在提高和低价基于磁共振(MR)的深度学习方法衰减校准(AC)(深度MRAC)在颅脑正电子发射体层成像(PET)/MRI的价值,并将结果发表在Radiology上。利用深度学习方法在MR图像中来模拟CT扫描从而建立PET/MR成像AC传输途径。深度卷积自动编码器进行识别空气、骨头、软组织并与CT图像进行匹配、训练。利用30例3D T1加权颅脑图像对该模型进行训练,通过比较生成的模拟CT扫描与CT扫描数据来评价10患者。利用推荐的方法对5例受试者进行即时PET/MR成像进行前瞻性研究。利用协方差分析和配对样本T检验进行统计学分析来比较PET深度MRAC重建错误和两种现存的基于MR成像的AC方法和基于CT的AC方法。深度MRAC能够提供准确的模拟CR扫描,空气、软组织和骨头的平均Dice系数分别为0.971 ± 0.005、 0.936 ± 0.011、0.803 ± 0.021。另外,深度MRAC能够提供良好的PET结果,在大部分的脑区平均错误低于1%。与基于Dixon 软组织和空气分割技术(-5.8% ± 3.1)和解剖学基于CT模板(-4.8% ± 2.2)比较,深度MRAC实

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    2018-01-08 feather89
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    2017-10-08 huagfeg
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    2017-10-06 方舒

    学习

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