J Endod:釉基质衍生物(Emdogain)在牙髓治疗中的应用:一项综合性的文献回顾

2018-04-15 lishiting MedSci原创

釉基质衍生物(EMD)是一种蛋白提取物,它常用于牙周缺损和软组织退缩的治疗。但是,它在牙髓治疗中的应用还处于探索阶段,特别是在牙髓再生治疗方面。这篇综述的目的是为了调查目前已发表的在牙髓治疗中应用EMD的文献。

釉基质衍生物(EMD)是一种蛋白提取物,它常用于牙周缺损和软组织退缩的治疗。但是,它在牙髓治疗中的应用还处于探索阶段,特别是在牙髓再生治疗方面。这篇综述的目的是为了调查目前已发表的在牙髓治疗中应用EMD的文献。研究通过不同的搜索词相结合对数据库中文章进行初次搜索,共检索出1089篇文献。进一步筛选出29篇合格文章,其中17篇为动物研究,12篇为人的系列病例报道以及临床试验。结果显示,将EMD用作直接盖髓剂的研究结果相对一分为二。对于EMD用于牙髓切断术的研究,仅有一项动物实验符合前面提出的标准。当EMD与氢氧化钙(Ca[OH]2), Portland cement, MTA相比较时,Ca(OH)2可以诱导更多的硬组织形成,而MTA则在临床和X线影像下表现最佳。而所查到的科学文章中,EMD对防止牙根吸收的有效性尚无明确定论。再生治疗中,施加EMD主要在牙根外表面的根尖孔区域会诱导牙骨质样组织的形成,并且这种新形成的硬组织展现出向根尖孔区域的内生长。结论:EMD应用于牙髓治疗中的结果变异很大,还需要更多的研究特别是在再植、再生和血运重建的题目上进行验证。原始出处:Wang HH, Sarm

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    2018-12-23 jxrzshh
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    2018-04-16 orangesking

    看看

    0

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    2018-04-15 wqkm

    ^_^^_^^_^

    0

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    2018-04-15 131****2916

    不错的文章值得推荐

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=1812666, encodeId=990a1812666df, content=<a href='/topic/show?id=d193900940b' target=_blank style='color:#2F92EE;'>#衍生物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=90094, encryptionId=d193900940b, topicName=衍生物)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=仁心济世, createdTime=Thu Jul 26 22:17:00 CST 2018, time=2018-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1757091, encodeId=51f91e57091c6, content=<a href='/topic/show?id=103b421e0e8' target=_blank style='color:#2F92EE;'>#基质#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42170, encryptionId=103b421e0e8, topicName=基质)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=281337296540, createdName=ms7899726347904398, createdTime=Thu Oct 25 01:17:00 CST 2018, time=2018-10-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1805879, encodeId=d46018058e97f, content=<a href='/topic/show?id=bf68e913035' target=_blank style='color:#2F92EE;'>#综合性的#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79130, encryptionId=bf68e913035, topicName=综合性的)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=198d2500149, createdName=12498bd5m16暂无昵称, createdTime=Fri Sep 14 04:17:00 CST 2018, time=2018-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1669659, encodeId=f2b0166965934, content=<a href='/topic/show?id=c7ca6e660ab' target=_blank style='color:#2F92EE;'>#牙髓#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67660, encryptionId=c7ca6e660ab, topicName=牙髓)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5eeb26562774, createdName=jxrzshh, createdTime=Sun Dec 23 06:17:00 CST 2018, time=2018-12-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1468058, encodeId=e8f5146805815, content=<a href='/topic/show?id=957b6e6754e' target=_blank style='color:#2F92EE;'>#牙髓治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67675, encryptionId=957b6e6754e, topicName=牙髓治疗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=876d6876924, createdName=hunizi007, createdTime=Tue Apr 17 12:17:00 CST 2018, time=2018-04-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=306435, encodeId=610730643540, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0aa31415219, createdName=orangesking, createdTime=Mon Apr 16 23:23:09 CST 2018, time=2018-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=306130, encodeId=e9b0306130d6, content=^_^^_^^_^, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Swp2ehfHpiciczeTntUyQOlIGMzQ705ic67sdMTVMbwTv7KbmlUvxrGvRSvQZjPkz7ib5tEDfIaORgczPtmHDpwojg/0, createdBy=c54b2163125, createdName=wqkm, createdTime=Sun Apr 15 22:35:56 CST 2018, time=2018-04-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=306127, encodeId=56ae30612eea, content=不错的文章值得推荐, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=04f22055142, createdName=131****2916, createdTime=Sun Apr 15 22:23:34 CST 2018, time=2018-04-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=306115, encodeId=8d7f306115f0, content=学习了.谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Sun Apr 15 21:41:28 CST 2018, time=2018-04-15, status=1, ipAttribution=)]
    2018-04-15 惠映实验室

    学习了.谢谢分享.

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