Arthritis Rheumatol:新发炎性腰背痛患者的临床演变

2018-03-04 xiangting MedSci原创

少部分新发IBP患者进展为SpA,而很多患者的疼痛消除了。

炎性腰背痛(IBP)通常是脊柱关节炎(SpA)的早期表现,但偶发性IBP患者的预后尚不清楚。这项研究在一个基于人群的队列中回顾性纵向研究了IBP患者的长期预后,以及进展为SpA的预测因子。

研究人员使用Rochester流行病学项目来查找1999年至2003年期间因腰背痛就诊的16至35岁患者,Rochester项目是一项针对美国明尼苏达州Olmsted郡居民的长期人群研究。筛查了这些患者是否存在新发IBP,并查看病历以收集SpA的临床、实验室和影像特征数据。随访至2016年7月。使用生存分析来分析其或进展为SpA,非SpA或腰背痛消除的竞争风险。使用递归分割来确定进展为SpA的预测因子。

在5304名腰背痛患者中,确定了124名新发IBP患者。在中位随访13.2年后,39名患者进展为SpA,15名患者诊断为非SpA,58名患者IBP消除。在10年时,SpA的可能性为30%,而IBP消除的可能性为43%。进展至SpA的最重要预测因子包括葡萄膜炎、男性和SpA家族史。

少部分新发IBP患者进展为SpA,而很多患者的疼痛消除了。IBP经常会消除这解释了IBP患病率(3-6%)和SpA患病率(0.5-1%)之间的差异。

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    2018-07-18 oliver181
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    2018-03-06 zhaojie88
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JBJS:戒烟可减轻腰背痛患者的疼痛

       许多研究表明吸烟与腰痛、腰椎间盘突出症、患者术后预后不良的风险增加具有关。骨与关节外科杂志(JBJS)2012年12月发表的一项最新研究还发现,患脊柱疾病和相关腰背部疼痛的吸烟者,与在8个月治疗期停止吸烟的脊柱疾病患者相比,不适感更为显著。        几乎所有的成年人都可能在某段时间内因背部疼痛或其

BMC Musculoskelet Disord:维生素D缺乏或与腰背痛有关

腰背痛由于其高发生率,是一种重要的公共健康问题,可导致活动受限,并且许多病例需要手术治疗。女性腰背痛比男性更常见,而且主要在绝经后女性。绝经后女性维生素D缺乏的患病率高,并与骨量丢失、肌肉减少症、椎体骨折和炎症反应相关,而骨量丢失、肌肉减少症、椎体骨折和炎症反应可能与腰背痛有关。为了评估腰背痛与维生素D缺乏之间的关系,以及有和没有维生素D缺乏女性之间卧床不起天数、不能上班天数和日常活动受限的差异,