J Clin Periodontol:唾液过氧化物酶活性和浓度与牙周健康之间关系的研究

2017-08-29 MedSci MedSci原创

髓过氧化物酶与牙周炎之间的关系已得到广泛的研究,唾液过氧化物酶和牙周炎之间的关系几乎没有得到重视。我们旨在研究牙周炎是否依赖于唾液过氧化物酶活性和浓度。

髓过氧化物酶与牙周炎之间的关系已得到广泛的研究,唾液过氧化物酶和牙周炎之间的关系几乎没有得到重视。我们旨在研究牙周炎是否依赖于唾液过氧化物酶活性和浓度。

在25-54岁的46名参与者的样本中进行了全面的探诊深度临床评估。为了尽量减少偏见,这些数据是通过普通人群的数据(波美拉尼亚的健康研究)进行修正的。我们使用5次重复测量1天的活性和浓度,我们评估了日常生物变异性,并提高了唾液过氧化物酶测量的可靠性。

结果:唾液过氧化物酶活性与探诊深度(四分位数范围效应= -0.48; 95%置信区间的粗略估计:-0.90至-0.31; p = .0052)相关,其作用不受唾液过氧化物酶浓度的影响。反过来,唾液过氧化物酶浓度的影响被唾液过氧化物酶活性干扰,并且活性更低。

结论:我们发现唾液过氧化物酶活性与探诊深度之间存在负相关关系。我们的研究结果表明,唾液过氧化物酶活性可能是抗牙周炎的保护因素。然而,还需要大量精心设计的研究来探索这种关联的因果机制。

原始出处:

Maral Memarzadeh Zahedani, Christian Schwahn, Romy Baguhl, et al. Association of salivary peroxidase activity and concentration with periodontal health: A validity study. Journal of clinical periodontology. 2017 August. doi: 10.1111/jcpe.12754

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    2017-09-06 feather89
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    2017-08-29 131****1460

    学习了受益匪浅.

    0

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    2017-08-29 1ddf0692m34(暂无匿称)

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