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Eur J Epidemiol：荟萃分析表明缺血性脑卒中与牙周炎相关

2016-06-27 MedSci MedSci原创

荟萃分析缺血性脑卒中牙周炎
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一些观察性研究已经表明牙周炎与脑缺血之间存在关联。本次荟萃分析旨在调查二者之间是否存在关联以及关联的强度。检索2016年3月2015日前发表在MEDLINE, EMBASE, Proceedings Web of Science以及Current Contents Connect上的研究，由两名评价者独立完成检索。纳入探究牙周炎和缺血性脑卒中的病例对照，横断面或队列研究。对纳入的研究进行质量评估。

一些观察性研究已经表明牙周炎与脑缺血之间存在关联。本次荟萃分析旨在调查二者之间是否存在关联以及关联的强度。

检索2016年3月2015日前发表在MEDLINE, EMBASE, Proceedings Web of Science以及Current Contents Connect上的研究，由两名评价者独立完成检索。纳入探究牙周炎和缺血性脑卒中的病例对照，横断面或队列研究。对纳入的研究进行质量评估。

结果获得414个研究摘要和57个潜在相关的研究全文。最终8项研究（5项病例对照和3项队列研究）符合纳入标准进行分析。

荟萃分析显示，牙周炎与缺血性脑卒中之间明显相关，汇总相对风险为2.52，且病例对照研究的汇总相对危险为3.04。

总而言之，此荟萃分析表明牙周炎和缺血性脑卒中之间存在关联。但是仍需要精心设计的前瞻性研究来为二者之间的关联提供强有力的证据。关于缺血性脑卒中的亚型，应行进一步的病例对照研究以探究不同类型的脑梗塞和牙周炎之间的关联。

原始出处：

Leira Y, Seoane J, et al.,Association between periodontitis and ischemic stroke: a systematic review and meta-analysis.Eur J Epidemiol. 2016 Jun 14.


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    2016-10-20 venlin

    #荟萃#

    0

  2. 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    2017-04-02 fangcong

    #荟萃分析#

    0

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    2016-12-11 ms7524819409032184

    #缺血性脑#

    0

  4. 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    2016-10-11 ylzr123

    好文值得点赞！继续关注学习。

    0

  5. 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    2016-10-11 1e10c84am36(暂无匿称)

    好文章，受益

    0

  6. 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    2017-01-21 柳叶一刀

    #缺血性#

    0

  7. 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GetPortalCommentsPageByObjectIdResponse(id=91901, encodeId=ec2e91901ea, content=有意思, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d0f31631005, createdName=保守主义, createdTime=Mon Jul 04 19:31:00 CST 2016, time=2016-07-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450471, encodeId=1a2914504e1c4, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab585558129, createdName=liuyong2982, createdTime=Wed Jun 29 13:32:00 CST 2016, time=2016-06-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=91498, encodeId=565c91498ae, content=整体看待身体, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=90f31612316, createdName=xiaotaiyang1, createdTime=Wed Jun 29 01:14:00 CST 2016, time=2016-06-29, status=1, ipAttribution=)]
    2016-08-16 huiminghappy

    ！！

    0

  8. 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    2016-07-04 保守主义

    有意思

    0

  9. 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    2016-06-29 liuyong2982

    #牙周#

    0

  10. 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GetPortalCommentsPageByObjectIdResponse(id=91498, encodeId=565c91498ae, content=整体看待身体, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=90f31612316, createdName=xiaotaiyang1, createdTime=Wed Jun 29 01:14:00 CST 2016, time=2016-06-29, status=1, ipAttribution=)]
    2016-06-29 xiaotaiyang1

    整体看待身体

    0

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JAMA：植物激素疗法治疗更年期症状是否效果更好？

在西方国家，40-50%的女性采用补充疗法来治疗更年期症状。本研究旨在确定植物疗法治疗绝经期症状，（包括潮热，盗汗，阴道干涩）的效果。研究人员检索了Ovid MEDLINE、EMBASE 及Cochrane Central数据库，确定了2016年3月27日之前发表的符合条件的研究。选择评估植物疗法治疗潮热、盗汗和阴道干涩的随机临床试验研究。最后共纳入了62项研究，包括6653名女性。由2名独立的研

J Dent Res：探究刷牙频率和龋齿之间的关系

刷牙是保持口腔保健的基本自我护理行为，每天刷牙两次已成为一种社会规范，但是目前关于刷牙频率的研究较少。本次系统回顾和荟萃分析旨在评估刷牙频率对龋齿发生的影响。检索MEDLINE、EMBASE、CINAHL及Cochrane数据库中相关的研究。由两名独立的评价者筛选研究，并进行质量评估。共进行了三个不同的荟萃分析：两个是基于刷牙频率分类的亚组分析的研究报道的龋齿的结果；另一个是以牙列类型作为亚组的龋

Br J Sports Med：阻力训练可降低代谢综合征患者的收缩压

目的：通过与对照组比较，评价抗阻训练对代谢综合征危险因素的影响。设计：荟萃分析比较抗阻训练干预和对照组。两个独立的评价者选择研究并且评估他们的质量和数据。应用固定效应模型计算抗阻训练和对照组的平均差异。数据源：搜索最早的记录到2015年1月10号MEDLINE， PEDro，EMBASE，SportDiscus和Cochrane图书馆数据库中的数据。选择研究的资格标准：比较抗阻训练和对照组对代谢综

BJCP：抗精神病药物的使用可增加心脏病的发病风险

BJCP：抗精神病药物的使用可增加心脏病的发病风险越来越多的研究关注抗精神病药与心肌梗死发生风险增加之间的可能关系。既往回顾性分析中确定的五项观察性研究对抗精神病药物的使用与心肌梗死发生风险之间的关联并未得出准确的结果；最近的研究得出了不同的结果。本研究纳入所有对比接受与未接受抗精神病药物治疗的患者心肌梗死发病率的观察性研究进行系统性的回顾和荟萃分析，以确定抗精神病药物的使用是否会影响心肌梗死的发

J Periodontol：荟萃分析表明牙周病可增加肺癌的发生风险

既往研究已经表明牙周病与许多系统性疾病（如心血管疾病和糖尿病）有关。而近期的研究又表明，牙周疾病或与肺癌的发生有关。但是，目前尚未确定二者之间确切的关联。因此，本研究旨通过荟萃分析探究牙周疾病与肺癌发生风险之间的关联。研究人员检索了2015年6月10日之前发表在PubMed、Scopus及ScienceDirect上的相关文章。包括探究牙周病患者肺癌发生风险的队列研究和病例对照研究。使用固定效应逆

Am J Cardiol：荟萃分析显示焦虑是心血管疾病的危险因素

焦虑是否是一系列心血管疾病的危险因素目前还不清楚。研究者的目的是确定焦虑和一系列心血管疾病的相关性。搜索MEDLINE和EMBASE中包括有无焦虑受试者的队列研究，包括焦虑，担心，创伤后应激障碍、恐怖性焦虑、急性焦虑症的受试者。研究者研究焦虑与心血管死亡率，主要心血管事件（定义为心血管死亡，卒中，冠状动脉心脏疾病和心脏衰竭复合预后），卒中，冠状动脉心脏病，心脏衰竭和房颤。研究者确定了46个队列研究