J Rheumatol:青少年银屑病关节炎中的肥胖状况

2017-12-25 xiangting MedSci原创

JPsA患者中超重和肥胖的患病率显著高于RF + polyJIA患者、RF-polyJIA患者和美国儿科人群。

成年银屑病关节炎患者出现肥胖和代谢综合征的风险升高,但关于青少年银屑病关节炎(JPsA)患儿肥胖的数据有限。这项研究评估了儿童关节炎和风湿病研究联盟(CARRA)登记的JPsA儿童的肥胖状况。

CARRA登记中的JPsA患者,根据美国疾病控制中心的建议分为非超重组和超重组,在基线和1年随访后,使用卡方检验、Fisher精确检验、T检验或Mann-Whitney U检验评估组间人口学和临床特征的差异。使用卡方拟合优度检验,将JPsA登记患者中超重状况的患病率与类风湿因子阳性和阴性多关节型幼年特发性关节炎(RF + polyJIA; RF-polyJIA)登记队列和美国儿科人群进行比较。

超重儿童占JPsA队列(n = 320)的36.3%。与非超重儿童相比,他们症状发作和风湿科医生首次评估时的年龄明显较大,并且患者/医师结果测量上得分显著更差。在1年的随访中,BMI的变化与临床特征或结局指标的变化无关。JPsA患者中超重和肥胖的患病率显著高于RF + polyJIA患者、RF-polyJIA患者和美国儿科人群。

在这个注册研究中,约1/5的JPsA患者肥胖,超过1/3超重。这与美国儿科人群相比明显超出了预期。需要对这个JPsA亚组进行适当的长期随访。

原始出处:

Aaida Samad, et al. Adiposity in Juvenile Psoriatic Arthritis.  J Rheumatol. 15 December 2017. 

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    2018-01-22 135****7952平儿

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    2017-12-27 lmm397
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    2017-12-25 131****1460

    学习了受益匪浅

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    2017-12-25 衣带渐宽

    学习

    0

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