JCEM:代谢综合征增加CVD死亡风险

2015-06-17 小田 译 医学论坛网

代谢综合征(MetS)是心血管疾病(CVD)死亡的危险因素。近期,韩国和英国学者们在韩国健康的年轻人中对MetS与全因死亡和心血管死亡的关系进行了研究,结果表明,MetS增加女性全因死亡风险和全部人群的CVD死亡风险;在这类人群中,增加的危险比(HR)归因于已经存在的糖尿病或高血压。相关论文近期在线发表于《临床内分泌代谢杂志》(J Clin Endocrinol Metab)。该回顾性研究纳入了1

代谢综合征(MetS)是心血管疾病(CVD)死亡的危险因素。近期,韩国和英国学者们在韩国健康的年轻人中对MetS与全因死亡和心血管死亡的关系进行了研究,结果表明,MetS增加女性全因死亡风险和全部人群的CVD死亡风险;在这类人群中,增加的危险比(HR)归因于已经存在的糖尿病或高血压。相关论文近期在线发表于《临床内分泌代谢杂志》(J Clin Endocrinol Metab)。

该回顾性研究纳入了155 971例平均年龄为41.8岁的受试者,对其随访3.7年(597 628.2 人-年)。根据有或无MetS分析全因死亡和CVD死亡风险。

结果显示,在随访期间共有542例受试者死亡。与不伴MetS的女性相比,伴MetS的女性经年龄校正后的全因死亡HR呈显著性增加,即使在校正混淆因素后仍然如此(HR 1.82)。与不伴MetS的受试者相比,伴MetS的受试者CVD死亡风险呈显著性增加,校正混淆因素后结果仍如此(HR 1.60);当从分析中排除基线有糖尿病或高血压的受试者后,这种显著性消失(HR 0.95)。

原始出处:

Sung KC1, Rhee EJ, Ryu S, Kim BJ, Kim BS, Lee WY, Oh KW, Bum Kim Y, Chung PW, Kim H, Byrne CD, Lee KB, Park SW.Increased Cardiovascular Mortality in Subjects With Metabolic Syndrome Is Largely Attributable to Diabetes and Hypertension in 159 971 Korean Adults.J Clin Endocrinol Metab.May 20, 2015.DOI: http://dx.doi.org/10.1210/jc.2014-4031

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    2016-02-04 achengzhao
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    2015-12-20 smallant2015
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    2015-06-25 huaxipanxing

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    2015-06-21 caierhong

    相辅相成

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    2015-06-21 caierhong

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    2015-06-21 caierhong

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