AJRCCM:二手烟+家族史,哮喘风险大幅增加

2013-09-09 佚名 中国医学论坛报

芬兰一项研究表明,当有二手烟暴露(SHS)时,有哮喘家族史的人出现成人期发作的哮喘风险明显增加。该论文8月27日在线发表于《美国呼吸和危重医学杂志》(Am J Respir Cri Care Med)。  研究纳入不吸烟的成人期发作的哮喘患者226人,无疾病对照组450人。结果为,父母患哮喘和近期SHS对哮喘的风险具有协同作用,SHS的校正比值比(OR)为1.97,父母患哮喘的校正OR为2.64,

芬兰一项研究表明,当有二手烟暴露(SHS)时,有哮喘家族史的人出现成人期发作的哮喘风险明显增加。该论文8月27日在线发表于《美国呼吸和危重医学杂志》(Am J Respir Cri Care Med)。  研究纳入不吸烟的成人期发作的哮喘患者226人,无疾病对照组450人。结果为,父母患哮喘和近期SHS对哮喘的风险具有协同作用,SHS的校正比值比(OR)为1.97,父母患哮喘的校正OR为2.64,两者的联合效应为12.69[95%可信区间(CI)为3.44~46.91],交互作用超额相对危险度(RERI)为9.08(95%CI为-0.22~43.18)。

原文阅读 

Lajunen TK, Jaakkola JJ, Jaakkola MS.The Synergistic Effect of Heredity and Exposure to Second-hand Smoke on Adult-onset Asthma.Am J Respir Crit Care Med. 2013 Aug 27.

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