J NUTR:研究发现乳糖不耐受与维生素D有关

2017-05-15 MedSci medicalxpress

来自多伦多大学的最新研究表明,乳糖(奶制品中的主要糖分) 不耐受的基因类型人群的血液中维生素D的含量比普通人群低。研究人员发现,那些有与乳糖不耐受症相关的基因(被称为LCT)的人摄入的奶制品比没有这种基因突变的人要低。乳糖不耐受的人血液中的维生素D含量也较低,这并不奇怪,因为奶制品中含有维生素D,而且大多数人都无法从太阳或其他食物中获得足够的维生素D。医学院营养学教授Ahmed El-Sohemy

来自多伦多大学的最新研究表明,乳糖(奶制品中的主要糖分) 不耐受的基因类型人群的血液中维生素D的含量比普通人群低。

研究人员发现,那些有与乳糖不耐受症相关的基因(被称为LCT)的人摄入的奶制品比没有这种基因突变的人要低。乳糖不耐受的人血液中的维生素D含量也较低,这并不奇怪,因为奶制品中含有维生素D,而且大多数人都无法从太阳或其他食物中获得足够的维生素D。

医学院营养学教授Ahmed El-Sohemy说:"我们并不惊讶,乳糖不耐受的人不吃乳制品,但是令我们惊讶的是,他们没有通过补充或吃其他食物来补偿这种关键的营养物质。Ahmed El-Sohemy与Ohood Alharbi(多伦多大学营养科学系的博士生)合作撰写了这项研究。

"这些调查结果表明,由于乳糖不耐受而限制乳制品摄入的人们需要加强这方面的了解。他们需要注意从其他强化食品中摄取足够的维生素D,比如某些品牌的橙汁,或者考虑尝试不含乳糖的奶制品。

研究人员还证实了先前的研究结果,即那些有乳糖不耐受的基因的人比那些不耐乳糖基因的人稍矮,这表明这些必需营养素的摄入不足会限制骨骼的生长。

他们第一次发现,只有一个基因--而不是两份拷贝--的人也会受到乳糖不耐受的影响,尽管程度较低,这表明乳糖不耐受的临床定义和基因分类可以扩大。

在不同种族群体中均发现了乳糖不耐受现象,但这一比例最大的是东亚人。

这项对1495名来自不同种族的加拿大人进行的研究将发表在2017年6月出版的《营养学杂志》上。

原文出处: Ohood Alharbi et al. Lactose Intolerance (-13910C>T) Genotype Is Associated with Plasma 25-Hydroxyvitamin D Concentrations in Caucasians: A Mendelian Randomization Study, The Journal of Nutrition (2017).

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