JAMA Int Med:动物蛋白 vs 植物蛋白,吃哪个才更健康?

2016-08-02 fsy 译 MedSci原创

目前,研究人员进行了一项探讨不同来源膳食蛋白影响的最大研究,该研究发现摄入大量动物来源的蛋白质--特别是加工和未加工的红肉--与死亡率较高有关,而摄入大量植物来源的蛋白质与死亡的风险较低有关。该研究的结果--分析了两项长期流行病学研究数据--于8月1日发表在 JAMA Internal Medicine杂志上。“总的来说,我们的研究结果支持了膳食蛋白质来源对于长期健康后果的重要性,”该研究的作者,

目前,研究人员进行了一项探讨不同来源膳食蛋白影响的最大规模研究,该研究发现摄入大量动物来源的蛋白质--特别是加工和未加工的红肉--与死亡率较高有关,而摄入大量植物来源的蛋白质与死亡的风险较低有关。该研究的结果--分析了两项长期流行病学研究数据--于8月1日发表在 JAMA Internal Medicine杂志上。

“总的来说,我们的研究结果支持了膳食蛋白质来源对于长期健康后果的重要性,”该研究的作者,马萨诸塞州总医院(MGH)临床和转化流行病学单位(CTEU),胃肠科,医学博士,Mingyang Song说。“虽然以前的研究主要集中在蛋白质摄入的总量--这是很重要的-- 但从广义饮食的角度来看,特别是人们获取蛋白质的食物,也是同样重要的。我们的研究结果也有公共卫生意义,可以帮助改善目前蛋白质的摄入量的饮食建议,不仅仅是蛋白质的量,具体的食物来源对于长期的健康也是至关重要的。”

虽然一些研究表明,在饮食中用蛋白质代替碳水化合物有几个健康的好处--包括体重管理,减少血压和其他心血管危险因素--作者指出,很少有研究探讨蛋白质的具体来源。那些研究规模都相对较小,并且都是基于参与者饮食的一次性评估。目前的研究分析了护士健康研究(NHS)和卫生专业人员随访研究(HPFS)的数据,这两项研究自上世纪80年代开始已经编制了超过17万参与者的全面健康数据。除了完成每两年一次的整体健康调查问卷,参加者还会每四年提供他们的饮食摄入量的信息--他们在过去的一年中,具体怎样经常食用特定种类的食物。

研究人员分析了NHS参与者超过30年的数据,HPFS参与者26年的数据,共计超过350万人-年。在这些时间段超过有36,000例死亡的研究参与者被记录--约9000例是由于心血管疾病,13,000例是由于癌症,其他14,000例是由于其他原因导致的。调整生活方式和其他饮食危险因素后,摄入较多的动物来源的蛋白质--任何类型的肉、蛋或奶制品--与死亡的发生率增加略微有关,而摄入较多的植物来源的蛋白质--面包、谷物、面食、豆类、坚果和豆类 --与较低的死亡率有关。

更仔细的分析表明,动物蛋白摄入量增加了死亡风险,但该联系只适用于那些生活方式不健康的参加者,他们至少有一个相关的因素--肥胖或体重过轻、大量饮酒、吸烟史或缺乏体力活动。事实上,该联系在健康生活方式的参与者中并不存在。基于蛋白质的具体来源分析表明,动物蛋白相关的死亡率风险主要适用于加工和未加工的红肉,其中包括牛肉和猪肉产品,而不包括鱼或家禽蛋白质产品。

“虽然我们预计,我们可能会发现该联系在健康的生活方式组中比较弱,但我们没想到这些联系完全不存在,”Song说。“但是,当我们更深入的分析数据,我们发现--动物蛋白摄入量水平相似--那些不健康的生活方式组中摄入更多的红肉,鸡蛋和高脂肪的乳制品,而健康的生活方式组则摄入更多的鱼和家禽。因此,我们怀疑两组间不同来源的动物蛋白在不健康的生活方式组中会导致更强的结果。”

他补充说,“我们的研究结果表明,人们应该考虑吃更多的植物蛋白,而不是动物蛋白,当补充动物蛋白时,鱼和鸡的来源可能是更好的选择。今后的研究应探讨不同植物蛋白和动物蛋白对整体健康的影响的潜在机制--以及不同来源的动物蛋白。”

原始出处:

Edward Giovannucci et al. Association of Animal and Plant Protein Intake With All-Cause and Cause-Specific Mortality. JAMA Internal Medicine,2016.8.1

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    2016-10-22 xuyong535
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    2016-09-11 1e10c84am36(暂无匿称)

    己拜读,受益匪浅

    0

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    2016-08-27 ylzr123

    赞!文章有深度,值得收藏拜读。

    0

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    2016-08-06 oo902

    哪个健康

    0

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