山东大学齐鲁医院成功实施左心耳封堵术

2015-02-28 于莉娟 田玉清 医学论坛网

     近日,山东大学齐鲁医院心内科为一名心房颤动患者成功实施左心耳封堵术。 患者74岁,女,体重90 kg,有高血压病史,持续房颤病史6年,曾辗转就诊于省内多家医院。1月26日来山东大学齐鲁医院就诊并住院,术前心脏超声示心房扩大、结构重构明显,经食道心脏超声排除左心耳血栓。脑卒中风险CHA2DS-VASc评分4分,其年卒中风险4.0%。患者口服抗凝药

    

近日,山东大学齐鲁医院心内科为一名心房颤动患者成功实施左心耳封堵术

患者74岁,女,体重90 kg,有高血压病史,持续房颤病史6年,曾辗转就诊于省内多家医院。1月26日来山东大学齐鲁医院就诊并住院,术前心脏超声示心房扩大、结构重构明显,经食道心脏超声排除左心耳血栓。脑卒中风险CHA2DS-VASc评分4分,其年卒中风险4.0%。患者口服抗凝药物治疗,剂量较大,而且凝血酶原国际标准化比率(INR)容易波动,其HAS-BLED出血风险评分3分,年出血风险达5.8%。经过术前讨论、综合评估后于1月31日在全麻下行左心耳封堵术,目的是预防血栓形成,避免血栓和出血事件发生。手术历时2小时,由该院心内科钟敬泉主任医师担任术者,术中经食道超声评估左心耳封堵良好,手术过程顺利,患者术后2天康复出院。随访1个月,患者无明显不适,复查超声无残余分流,手术效果良好。患者逐渐停用抗凝药物,预防了血栓栓塞发生的同时避免了出血风险。

心房颤动(房颤)是临床上最常见的心律失常,普通人群房颤发病率为0.5%-1.3%,随年龄增长其发病率逐年升高,50岁以上,年龄每增加10岁,发病率增加1倍,80岁以上人群房颤发病率高达80%。保守估计我国目前房颤患者数量超过800万。房颤是引起缺血性脑卒中的主要原因之一。非瓣膜病性房颤卒中风险比正常人高5倍,瓣膜性房颤卒中风险更是高出正常人17.6倍。每年罹患卒中患者中约20%-25%归因于房颤。90%非瓣膜病性房颤血栓形成于左心耳,60%瓣膜性房颤血栓源于左心耳。抗凝治疗是预防房颤患者血栓栓塞的重要治疗方法,传统的方法主要依赖口服抗凝药物。然而由于口服抗凝药物治疗窗窄、患者依从性、需要经常监测凝血指标、新型口服抗凝药价格昂贵等诸多弊端制约真实诊治过程中房颤的规范化抗凝治疗。左心耳封堵术是近几年新兴出现的房颤患者预防血栓的技术,对于抗凝药物有禁忌或不能耐受抗凝药物的患者是一种新的治疗方式。经过PROTECT-AF、CAP、ASAP、PREVAIL等临床试验证实左心耳封堵术不劣于口服抗凝药华法林,能显著提高患者生活质量,手术安全性较高。

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    2015-03-16 ycmayy
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    2015-03-04 drhqh240

    心内科紧跟世界潮流啊

    0

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    2015-03-02 jxrzshh
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    2015-02-28 MedSci客户端网友

    389…

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    2015-02-28 MedSci客户端网友

    是!wabI'muql8g啊‘

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