Neurology:精神类共病与多发性硬化残疾程度进展相关

2018-03-11 zhangfan MedSci原创

研究认为对于多发性硬化患者,精神系统共病率较高,是疾病残疾程度进展的标志

有证据表明多发性硬化(MS)患者出现其他共病是疾病进展的征兆。近日研究人员开展大规模人群队列研究,考察MS患者残疾程度与精神类共病之间的关系。

本次回顾性队列,前瞻性的考察了加拿大不列颠哥伦比亚省和新斯科舍省临床和人口卫生行政数据,识别存在抑郁症、焦虑或双相情感障的MS患者资料,采用多变量线性回归模型以及EDSS残疾状态评分,考察精神类共疾病与MS残疾之间的关系。

总计2312名MS患者参与研究,随访10.5年,其中35.8%的患者存在精神情绪异常。情绪或焦虑症患者其EDSS得分升高(β= 0.28, p = 0.0002, 根据疾病时间和病程、年龄、性别、社会经济状况、身体共病数和疗法等进行调整),该相关性在女性患者中更为显著(β= 0.31, p = 0.0004),但男性患者中显著性降低(β=0.22, p = 0.17)。

研究认为对于多发性硬化患者,精神系统共病率较高,是疾病残疾程度进展的标志。

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    2018-08-12 yinhl1978
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    2018-05-08 jml2009
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    2018-03-18 虈亣靌

    优质资源.共同学习

    0

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    2018-03-12 为你把脉

    v股海护航哈哈哈姐好

    0

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    2018-03-11 1ddf0692m34(暂无匿称)

    学习了.涨知识

    0

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    2018-03-11 为你把脉

    vv该好好还好还好哈

    0

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    2018-03-11 执着追梦

    学习.谢谢分享

    0

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    2018-03-11 1dd8c52fm63(暂无匿称)

    了解了解.学习学习

    0

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